These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

362 related articles for article (PubMed ID: 11430832)

  • 1. The Peutz-Jegher gene product LKB1 is a mediator of p53-dependent cell death.
    Karuman P; Gozani O; Odze RD; Zhou XC; Zhu H; Shaw R; Brien TP; Bozzuto CD; Ooi D; Cantley LC; Yuan J
    Mol Cell; 2001 Jun; 7(6):1307-19. PubMed ID: 11430832
    [TBL] [Abstract][Full Text] [Related]  

  • 2. LKB1--a master tumour suppressor of the small intestine and beyond.
    Yoo LI; Chung DC; Yuan J
    Nat Rev Cancer; 2002 Jul; 2(7):529-35. PubMed ID: 12094239
    [No Abstract]   [Full Text] [Related]  

  • 3. Wnt signaling may be activated in a subset of Peutz-Jeghers syndrome polyps closely correlating to LKB1 expression.
    Ma Y; Zhang G; Fu X; Xia O; Zhan C; Li L; Wang Z; Wu B
    Oncol Rep; 2010 Jun; 23(6):1569-76. PubMed ID: 20428811
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Molecular genetic alterations in hamartomatous polyps and carcinomas of patients with Peutz-Jeghers syndrome.
    Entius MM; Keller JJ; Westerman AM; van Rees BP; van Velthuysen ML; de Goeij AF; Wilson JH; Giardiello FM; Offerhaus GJ
    J Clin Pathol; 2001 Feb; 54(2):126-31. PubMed ID: 11215281
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Functional analysis of LKB1/STK11 mutants and two aberrant isoforms found in Peutz-Jeghers Syndrome patients.
    Boudeau J; Kieloch A; Alessi DR; Stella A; Guanti G; Resta N
    Hum Mutat; 2003 Feb; 21(2):172. PubMed ID: 12552571
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Nasal polyposis in Peutz-Jeghers syndrome: a distinct histopathological and molecular genetic entity.
    de Leng WW; Westerman AM; Weterman MA; Jansen M; van Dekken H; Giardiello FM; de Rooij FW; Paul Wilson JH; Offerhaus GJ; Keller JJ
    J Clin Pathol; 2007 Apr; 60(4):392-6. PubMed ID: 16775120
    [TBL] [Abstract][Full Text] [Related]  

  • 7. LKB1 interacts with and phosphorylates PTEN: a functional link between two proteins involved in cancer predisposing syndromes.
    Mehenni H; Lin-Marq N; Buchet-Poyau K; Reymond A; Collart MA; Picard D; Antonarakis SE
    Hum Mol Genet; 2005 Aug; 14(15):2209-19. PubMed ID: 15987703
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutation of Lkb1 and p53 genes exert a cooperative effect on tumorigenesis.
    Wei C; Amos CI; Stephens LC; Campos I; Deng JM; Behringer RR; Rashid A; Frazier ML
    Cancer Res; 2005 Dec; 65(24):11297-303. PubMed ID: 16357136
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Somatic mutations of LKB1 and beta-catenin genes in gastrointestinal polyps from patients with Peutz-Jeghers syndrome.
    Miyaki M; Iijima T; Hosono K; Ishii R; Yasuno M; Mori T; Toi M; Hishima T; Shitara N; Tamura K; Utsunomiya J; Kobayashi N; Kuroki T; Iwama T
    Cancer Res; 2000 Nov; 60(22):6311-3. PubMed ID: 11103790
    [TBL] [Abstract][Full Text] [Related]  

  • 10. LKB1, a novel serine/threonine protein kinase and potential tumour suppressor, is phosphorylated by cAMP-dependent protein kinase (PKA) and prenylated in vivo.
    Collins SP; Reoma JL; Gamm DM; Uhler MD
    Biochem J; 2000 Feb; 345 Pt 3(Pt 3):673-80. PubMed ID: 10642527
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Restoration of silenced Peutz-Jeghers syndrome gene, LKB1, induces apoptosis in pancreatic carcinoma cells.
    Qanungo S; Haldar S; Basu A
    Neoplasia; 2003; 5(4):367-74. PubMed ID: 14511408
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Phosphorylation of the protein kinase mutated in Peutz-Jeghers cancer syndrome, LKB1/STK11, at Ser431 by p90(RSK) and cAMP-dependent protein kinase, but not its farnesylation at Cys(433), is essential for LKB1 to suppress cell vrowth.
    Sapkota GP; Kieloch A; Lizcano JM; Lain S; Arthur JS; Williams MR; Morrice N; Deak M; Alessi DR
    J Biol Chem; 2001 Jun; 276(22):19469-82. PubMed ID: 11297520
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A novel de novo mutation in LKB1 gene in a Chinese Peutz Jeghers syndrome patient significantly diminished p53 activity.
    Liu L; Du X; Nie J
    Clin Res Hepatol Gastroenterol; 2011 Mar; 35(3):221-6. PubMed ID: 21411391
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Elevation of WNT5A expression in polyp formation in Lkb1+/- mice and Peutz-Jeghers syndrome.
    Lai C; Robinson J; Clark S; Stamp G; Poulsom R; Silver A
    J Pathol; 2011 Apr; 223(5):584-92. PubMed ID: 21341271
    [TBL] [Abstract][Full Text] [Related]  

  • 15. [Clinical characteristics and mutation analysis of the LKB1 gene in a Peutz-Jeghers syndrome pedigree].
    Pan J; Li M; Jin Y; Zhang XM; Zhu M; Chen SQ
    Zhonghua Er Ke Za Zhi; 2013 Feb; 51(2):145-9. PubMed ID: 23527983
    [TBL] [Abstract][Full Text] [Related]  

  • 16. De novo germline mutation in the serine-threonine kinase STK11/LKB1 gene associated with Peutz-Jeghers syndrome.
    Hernan I; Roig I; Martin B; Gamundi MJ; Martinez-Gimeno M; Carballo M
    Clin Genet; 2004 Jul; 66(1):58-62. PubMed ID: 15200509
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Correlation of staining for LKB1 and COX-2 in hamartomatous polyps and carcinomas from patients with Peutz-Jeghers syndrome.
    Wei C; Amos CI; Rashid A; Sabripour M; Nations L; McGarrity TJ; Frazier ML
    J Histochem Cytochem; 2003 Dec; 51(12):1665-72. PubMed ID: 14623934
    [TBL] [Abstract][Full Text] [Related]  

  • 18. [Peutz-Jeghers syndrome].
    Miyaki M
    Nihon Rinsho; 2000 Jul; 58(7):1400-4. PubMed ID: 10921312
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Intestinal renin-angiotensin system is stimulated after deletion of Lkb1.
    Shorning BY; Jardé T; McCarthy A; Ashworth A; de Leng WW; Offerhaus GJ; Resta N; Dale T; Clarke AR
    Gut; 2012 Feb; 61(2):202-13. PubMed ID: 21813469
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Regulation of the TSC pathway by LKB1: evidence of a molecular link between tuberous sclerosis complex and Peutz-Jeghers syndrome.
    Corradetti MN; Inoki K; Bardeesy N; DePinho RA; Guan KL
    Genes Dev; 2004 Jul; 18(13):1533-8. PubMed ID: 15231735
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 19.