BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

273 related articles for article (PubMed ID: 11431323)

  • 1. Formation of intracranial tumors by genetically modified human astrocytes defines four pathways critical in the development of human anaplastic astrocytoma.
    Sonoda Y; Ozawa T; Hirose Y; Aldape KD; McMahon M; Berger MS; Pieper RO
    Cancer Res; 2001 Jul; 61(13):4956-60. PubMed ID: 11431323
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Akt pathway activation converts anaplastic astrocytoma to glioblastoma multiforme in a human astrocyte model of glioma.
    Sonoda Y; Ozawa T; Aldape KD; Deen DF; Berger MS; Pieper RO
    Cancer Res; 2001 Sep; 61(18):6674-8. PubMed ID: 11559533
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A genetically tractable model of human glioma formation.
    Rich JN; Guo C; McLendon RE; Bigner DD; Wang XF; Counter CM
    Cancer Res; 2001 May; 61(9):3556-60. PubMed ID: 11325817
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Reduction in mortalin level by its antisense expression causes senescence-like growth arrest in human immortalized cells.
    Wadhwa R; Takano S; Taira K; Kaul SC
    J Gene Med; 2004 Apr; 6(4):439-44. PubMed ID: 15079818
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ink4a-Arf loss cooperates with KRas activation in astrocytes and neural progenitors to generate glioblastomas of various morphologies depending on activated Akt.
    Uhrbom L; Dai C; Celestino JC; Rosenblum MK; Fuller GN; Holland EC
    Cancer Res; 2002 Oct; 62(19):5551-8. PubMed ID: 12359767
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Astrocyte-specific expression of activated p21-ras results in malignant astrocytoma formation in a transgenic mouse model of human gliomas.
    Ding H; Roncari L; Shannon P; Wu X; Lau N; Karaskova J; Gutmann DH; Squire JA; Nagy A; Guha A
    Cancer Res; 2001 May; 61(9):3826-36. PubMed ID: 11325859
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The role of HPV oncoproteins and cellular factors in maintenance of hTERT expression in cervical carcinoma cells.
    Jeong Seo E; Jung Kim H; Jae Lee C; Tae Kang H; Seong Hwang E
    Gynecol Oncol; 2004 Jul; 94(1):40-7. PubMed ID: 15262117
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Oncogenic transformation of human ovarian surface epithelial cells with defined cellular oncogenes.
    Sasaki R; Narisawa-Saito M; Yugawa T; Fujita M; Tashiro H; Katabuchi H; Kiyono T
    Carcinogenesis; 2009 Mar; 30(3):423-31. PubMed ID: 19126650
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Treatment of malignant glioma cells with the transfer of constitutively active caspase-6 using the human telomerase catalytic subunit (human telomerase reverse transcriptase) gene promoter.
    Komata T; Kondo Y; Kanzawa T; Hirohata S; Koga S; Sumiyoshi H; Srinivasula SM; Barna BP; Germano IM; Takakura M; Inoue M; Alnemri ES; Shay JW; Kyo S; Kondo S
    Cancer Res; 2001 Aug; 61(15):5796-802. PubMed ID: 11479218
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Absence of cancer-associated changes in human fibroblasts immortalized with telomerase.
    Morales CP; Holt SE; Ouellette M; Kaur KJ; Yan Y; Wilson KS; White MA; Wright WE; Shay JW
    Nat Genet; 1999 Jan; 21(1):115-8. PubMed ID: 9916803
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Oligodendrogliomas result from the expression of an activated mutant epidermal growth factor receptor in a RAS transgenic mouse astrocytoma model.
    Ding H; Shannon P; Lau N; Wu X; Roncari L; Baldwin RL; Takebayashi H; Nagy A; Gutmann DH; Guha A
    Cancer Res; 2003 Mar; 63(5):1106-13. PubMed ID: 12615729
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Abrogation of the retinoblastoma tumor suppressor checkpoint during keratinocyte immortalization is not sufficient for induction of centrosome-mediated genomic instability.
    Piboonniyom SO; Duensing S; Swilling NW; Hasskarl J; Hinds PW; Münger K
    Cancer Res; 2003 Jan; 63(2):476-83. PubMed ID: 12543805
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Both Rb/p16INK4a inactivation and telomerase activity are required to immortalize human epithelial cells.
    Kiyono T; Foster SA; Koop JI; McDougall JK; Galloway DA; Klingelhutz AJ
    Nature; 1998 Nov; 396(6706):84-8. PubMed ID: 9817205
    [TBL] [Abstract][Full Text] [Related]  

  • 14. H-Ras increases urokinase expression and cell invasion in genetically modified human astrocytes through Ras/Raf/MEK signaling pathway.
    Zhao Y; Xiao A; Dipierro CG; Abdel-Fattah R; Amos S; Redpath GT; Carpenter JE; Pieper RO; Hussaini IM
    Glia; 2008 Jun; 56(8):917-24. PubMed ID: 18383343
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Overexpression of vascular endothelial growth factor isoforms drives oxygenation and growth but not progression to glioblastoma multiforme in a human model of gliomagenesis.
    Sonoda Y; Kanamori M; Deen DF; Cheng SY; Berger MS; Pieper RO
    Cancer Res; 2003 Apr; 63(8):1962-8. PubMed ID: 12702589
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Early upregulation of cyclooxygenase-2 in human papillomavirus type 16 and telomerase-induced immortalization of human esophageal epithelial cells.
    Zhuang ZH; Tsao SW; Deng W; Wang JD; Xia HH; He H; Feng HC; Wang LD; Gu Q; Lam SK; Lin MC; Kung HF; Wong BC
    J Gastroenterol Hepatol; 2008 Oct; 23(10):1613-20. PubMed ID: 18717758
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Astrocyte-specific expression of CDK4 is not sufficient for tumor formation, but cooperates with p53 heterozygosity to provide a growth advantage for astrocytes in vivo.
    Huang ZY; Baldwin RL; Hedrick NM; Gutmann DH
    Oncogene; 2002 Feb; 21(9):1325-34. PubMed ID: 11857076
    [TBL] [Abstract][Full Text] [Related]  

  • 18. A P53-dependent, telomere-independent proliferative life span barrier in human astrocytes consistent with the molecular genetics of glioma development.
    Evans RJ; Wyllie FS; Wynford-Thomas D; Kipling D; Jones CJ
    Cancer Res; 2003 Aug; 63(16):4854-61. PubMed ID: 12941806
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ha-Ras(G12V) induces senescence in primary and immortalized human esophageal keratinocytes with p53 dysfunction.
    Takaoka M; Harada H; Deramaudt TB; Oyama K; Andl CD; Johnstone CN; Rhoades B; Enders GH; Opitz OG; Nakagawa H
    Oncogene; 2004 Sep; 23(40):6760-8. PubMed ID: 15273725
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Combined activation of Ras and Akt in neural progenitors induces glioblastoma formation in mice.
    Holland EC; Celestino J; Dai C; Schaefer L; Sawaya RE; Fuller GN
    Nat Genet; 2000 May; 25(1):55-7. PubMed ID: 10802656
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.