BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

481 related articles for article (PubMed ID: 11431359)

  • 1. Role of the hMLH1 DNA mismatch repair protein in fluoropyrimidine-mediated cell death and cell cycle responses.
    Meyers M; Wagner MW; Hwang HS; Kinsella TJ; Boothman DA
    Cancer Res; 2001 Jul; 61(13):5193-201. PubMed ID: 11431359
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Defective expression of the DNA mismatch repair protein, MLH1, alters G2-M cell cycle checkpoint arrest following ionizing radiation.
    Davis TW; Wilson-Van Patten C; Meyers M; Kunugi KA; Cuthill S; Reznikoff C; Garces C; Boland CR; Kinsella TJ; Fishel R; Boothman DA
    Cancer Res; 1998 Feb; 58(4):767-78. PubMed ID: 9485033
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Effect of H(2)O(2) on cell cycle and survival in DNA mismatch repair-deficient and -proficient cell lines.
    Chang DK; Goel A; Ricciardiello L; Lee DH; Chang CL; Carethers JM; Boland CR
    Cancer Lett; 2003 Jun; 195(2):243-51. PubMed ID: 12767533
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Loss of DNA mismatch repair imparts defective cdc2 signaling and G(2) arrest responses without altering survival after ionizing radiation.
    Yan T; Schupp JE; Hwang HS; Wagner MW; Berry SE; Strickfaden S; Veigl ML; Sedwick WD; Boothman DA; Kinsella TJ
    Cancer Res; 2001 Nov; 61(22):8290-7. PubMed ID: 11719462
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The mismatch repair protein, hMLH1, mediates 5-substituted halogenated thymidine analogue cytotoxicity, DNA incorporation, and radiosensitization in human colon cancer cells.
    Berry SE; Garces C; Hwang HS; Kunugi K; Meyers M; Davis TW; Boothman DA; Kinsella TJ
    Cancer Res; 1999 Apr; 59(8):1840-5. PubMed ID: 10213489
    [TBL] [Abstract][Full Text] [Related]  

  • 6. DNA mismatch repair (MMR) mediates 6-thioguanine genotoxicity by introducing single-strand breaks to signal a G2-M arrest in MMR-proficient RKO cells.
    Yan T; Berry SE; Desai AB; Kinsella TJ
    Clin Cancer Res; 2003 Jun; 9(6):2327-34. PubMed ID: 12796402
    [TBL] [Abstract][Full Text] [Related]  

  • 7. MLH1 deficiency enhances radiosensitization with 5-fluorodeoxyuridine by increasing DNA mismatches.
    Flanagan SA; Krokosky CM; Mannava S; Nikiforov MA; Shewach DS
    Mol Pharmacol; 2008 Sep; 74(3):863-71. PubMed ID: 18535288
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Role of hMLH1 promoter hypermethylation in drug resistance to 5-fluorouracil in colorectal cancer cell lines.
    Arnold CN; Goel A; Boland CR
    Int J Cancer; 2003 Aug; 106(1):66-73. PubMed ID: 12794758
    [TBL] [Abstract][Full Text] [Related]  

  • 9. MSH3 mismatch repair protein regulates sensitivity to cytotoxic drugs and a histone deacetylase inhibitor in human colon carcinoma cells.
    Park JM; Huang S; Tougeron D; Sinicrope FA
    PLoS One; 2013; 8(5):e65369. PubMed ID: 23724141
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Decreased expression of hMLH1 correlates with reduced 5-fluorouracil-mediated apoptosis in colon cancer cells.
    Fujita H; Kato J; Horii J; Harada K; Hiraoka S; Shiraha H; Sakaguchi K; Shiratori Y
    Oncol Rep; 2007 Nov; 18(5):1129-37. PubMed ID: 17914563
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Brostallicin (PNU-166196)--a new DNA minor groove binder that retains sensitivity in DNA mismatch repair-deficient tumour cells.
    Fedier A; Fowst C; Tursi J; Geroni C; Haller U; Marchini S; Fink D
    Br J Cancer; 2003 Oct; 89(8):1559-65. PubMed ID: 14562032
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Chemotherapy-induced O(6)-benzylguanine-resistant alkyltransferase mutations in mismatch-deficient colon cancer.
    Liu L; Schwartz S; Davis BM; Gerson SL
    Cancer Res; 2002 Jun; 62(11):3070-6. PubMed ID: 12036916
    [TBL] [Abstract][Full Text] [Related]  

  • 13. DNA mismatch repair-dependent response to fluoropyrimidine-generated damage.
    Meyers M; Wagner MW; Mazurek A; Schmutte C; Fishel R; Boothman DA
    J Biol Chem; 2005 Feb; 280(7):5516-26. PubMed ID: 15611052
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Antisense inhibition of hMLH1 is not sufficient for loss of DNA mismatch repair function in the HCT116+chromosome 3 cell line.
    Chauhan DP; Yang Q; Carethers JM; Marra G; Chang CL; Chamberlain SM; Boland CR
    Clin Cancer Res; 2000 Oct; 6(10):3827-31. PubMed ID: 11051225
    [TBL] [Abstract][Full Text] [Related]  

  • 15. 5-fluoro-2'-deoxyuridine-induced cdc25A accumulation correlates with premature mitotic entry and clonogenic death in human colon cancer cells.
    Parsels LA; Parsels JD; Tai DC; Coughlin DJ; Maybaum J
    Cancer Res; 2004 Sep; 64(18):6588-94. PubMed ID: 15374972
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Signalling cell cycle arrest and cell death through the MMR System.
    O'Brien V; Brown R
    Carcinogenesis; 2006 Apr; 27(4):682-92. PubMed ID: 16332722
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Acidic tumor microenvironment downregulates hMLH1 but does not diminish 5-fluorouracil chemosensitivity.
    Iwaizumi M; Tseng-Rogenski S; Carethers JM
    Mutat Res; 2013; 747-748():19-27. PubMed ID: 23643670
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Reversal of drug resistance in human tumor xenografts by 2'-deoxy-5-azacytidine-induced demethylation of the hMLH1 gene promoter.
    Plumb JA; Strathdee G; Sludden J; Kaye SB; Brown R
    Cancer Res; 2000 Nov; 60(21):6039-44. PubMed ID: 11085525
    [TBL] [Abstract][Full Text] [Related]  

  • 19. DNA damage signaling in response to 5-fluorouracil in three colorectal cancer cell lines with different mismatch repair and TP53 status.
    Adamsen BL; Kravik KL; De Angelis PM
    Int J Oncol; 2011 Sep; 39(3):673-82. PubMed ID: 21674128
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Mismatch repair proteins are activators of toxic responses to chromium-DNA damage.
    Peterson-Roth E; Reynolds M; Quievryn G; Zhitkovich A
    Mol Cell Biol; 2005 May; 25(9):3596-607. PubMed ID: 15831465
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 25.