BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

243 related articles for article (PubMed ID: 11438644)

  • 1. Mutational analysis of the Cy motif from p21 reveals sequence degeneracy and specificity for different cyclin-dependent kinases.
    Wohlschlegel JA; Dwyer BT; Takeda DY; Dutta A
    Mol Cell Biol; 2001 Aug; 21(15):4868-74. PubMed ID: 11438644
    [TBL] [Abstract][Full Text] [Related]  

  • 2. HIRA, the human homologue of yeast Hir1p and Hir2p, is a novel cyclin-cdk2 substrate whose expression blocks S-phase progression.
    Hall C; Nelson DM; Ye X; Baker K; DeCaprio JA; Seeholzer S; Lipinski M; Adams PD
    Mol Cell Biol; 2001 Mar; 21(5):1854-65. PubMed ID: 11238922
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Cyclin-binding motifs are essential for the function of p21CIP1.
    Chen J; Saha P; Kornbluth S; Dynlacht BD; Dutta A
    Mol Cell Biol; 1996 Sep; 16(9):4673-82. PubMed ID: 8756624
    [TBL] [Abstract][Full Text] [Related]  

  • 4. The association of cyclin A and cyclin kinase inhibitor p21 in response to gamma-irradiation requires the CDK2 binding region, but not the Cy motif.
    Fukuchi K; Nakamura K; Ichimura S; Tatsumi K; Gomi K
    Biochim Biophys Acta; 2003 Oct; 1642(3):163-71. PubMed ID: 14572899
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Characterization of p21Cip1/Waf1 peptide domains required for cyclin E/Cdk2 and PCNA interaction.
    Chen IT; Akamatsu M; Smith ML; Lung FD; Duba D; Roller PP; Fornace AJ; O'Connor PM
    Oncogene; 1996 Feb; 12(3):595-607. PubMed ID: 8637717
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of a cyclin-cdk2 recognition motif present in substrates and p21-like cyclin-dependent kinase inhibitors.
    Adams PD; Sellers WR; Sharma SK; Wu AD; Nalin CM; Kaelin WG
    Mol Cell Biol; 1996 Dec; 16(12):6623-33. PubMed ID: 8943316
    [TBL] [Abstract][Full Text] [Related]  

  • 7. p21 contains independent binding sites for cyclin and cdk2: both sites are required to inhibit cdk2 kinase activity.
    Fotedar R; Fitzgerald P; Rousselle T; Cannella D; Dorée M; Messier H; Fotedar A
    Oncogene; 1996 May; 12(10):2155-64. PubMed ID: 8668341
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The structural basis for specificity of substrate and recruitment peptides for cyclin-dependent kinases.
    Brown NR; Noble ME; Endicott JA; Johnson LN
    Nat Cell Biol; 1999 Nov; 1(7):438-43. PubMed ID: 10559988
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Site-directed mutant p21 proteins defective in both inhibition of E2F-regulated transcription and disruption of E2F-p130-cyclin-cdk2 complexes.
    Robles SJ; Shiyanov P; Aristodemo GT; Raychaudhuri P; Adami GR
    DNA Cell Biol; 1998 Jan; 17(1):9-18. PubMed ID: 9468218
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A bipartite substrate recognition motif for cyclin-dependent kinases.
    Takeda DY; Wohlschlegel JA; Dutta A
    J Biol Chem; 2001 Jan; 276(3):1993-7. PubMed ID: 11067844
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Specificity determinants of recruitment peptides bound to phospho-CDK2/cyclin A.
    Lowe ED; Tews I; Cheng KY; Brown NR; Gul S; Noble ME; Gamblin SJ; Johnson LN
    Biochemistry; 2002 Dec; 41(52):15625-34. PubMed ID: 12501191
    [TBL] [Abstract][Full Text] [Related]  

  • 12. The amino terminus of Cdk2 binds p21.
    Moskowitz NK; Borao FJ; Dardashti O; Cohen HD; Germino FJ
    Oncol Res; 1996; 8(9):343-52. PubMed ID: 8979268
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Reversal of growth suppression by p107 via direct phosphorylation by cyclin D1/cyclin-dependent kinase 4.
    Leng X; Noble M; Adams PD; Qin J; Harper JW
    Mol Cell Biol; 2002 Apr; 22(7):2242-54. PubMed ID: 11884610
    [TBL] [Abstract][Full Text] [Related]  

  • 14. CCAAT/enhancer-binding protein-alpha cooperates with p21 to inhibit cyclin-dependent kinase-2 activity and induces growth arrest independent of DNA binding.
    Harris TE; Albrecht JH; Nakanishi M; Darlington GJ
    J Biol Chem; 2001 Aug; 276(31):29200-9. PubMed ID: 11369759
    [TBL] [Abstract][Full Text] [Related]  

  • 15. p21CIP1 and Cdc25A: competition between an inhibitor and an activator of cyclin-dependent kinases.
    Saha P; Eichbaum Q; Silberman ED; Mayer BJ; Dutta A
    Mol Cell Biol; 1997 Aug; 17(8):4338-45. PubMed ID: 9234691
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Structural studies of p21Waf1/Cip1/Sdi1 in the free and Cdk2-bound state: conformational disorder mediates binding diversity.
    Kriwacki RW; Hengst L; Tennant L; Reed SI; Wright PE
    Proc Natl Acad Sci U S A; 1996 Oct; 93(21):11504-9. PubMed ID: 8876165
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The protein SET regulates the inhibitory effect of p21(Cip1) on cyclin E-cyclin-dependent kinase 2 activity.
    Estanyol JM; Jaumot M; Casanovas O; Rodriguez-Vilarrupla A; Agell N; Bachs O
    J Biol Chem; 1999 Nov; 274(46):33161-5. PubMed ID: 10551888
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Substrate recruitment to cyclin-dependent kinase 2 by a multipurpose docking site on cyclin A.
    Schulman BA; Lindstrom DL; Harlow E
    Proc Natl Acad Sci U S A; 1998 Sep; 95(18):10453-8. PubMed ID: 9724724
    [TBL] [Abstract][Full Text] [Related]  

  • 19. TGF-beta-mediated cell cycle arrest of HPV16-immortalized human ectocervical cells correlates with decreased E6/E7 mRNA and increased p53 and p21(WAF-1) expression.
    Rorke EA; Zhang D; Choo CK; Eckert RL; Jacobberger JW
    Exp Cell Res; 2000 Aug; 259(1):149-57. PubMed ID: 10942587
    [TBL] [Abstract][Full Text] [Related]  

  • 20. G1 phase accumulation induced by UCN-01 is associated with dephosphorylation of Rb and CDK2 proteins as well as induction of CDK inhibitor p21/Cip1/WAF1/Sdi1 in p53-mutated human epidermoid carcinoma A431 cells.
    Akiyama T; Yoshida T; Tsujita T; Shimizu M; Mizukami T; Okabe M; Akinaga S
    Cancer Res; 1997 Apr; 57(8):1495-501. PubMed ID: 9108451
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 13.