BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

136 related articles for article (PubMed ID: 11446731)

  • 1. Requirement of thrombopoietin-induced activation of ERK for megakaryocyte differentiation and of p38 for erythroid differentiation.
    Miyazaki R; Ogata H; Kobayashi Y
    Ann Hematol; 2001 May; 80(5):284-91. PubMed ID: 11446731
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A functional role of mitogen-activated protein kinases, erk1 and erk2, in the differentiation of a human leukemia cell line, UT-7/GM: a possible key factor for cell fate determination toward erythroid and megakaryocytic lineages.
    Uchida M; Kirito K; Shimizu R; Miura Y; Ozawa K; Komatsu N
    Int J Hematol; 2001 Jan; 73(1):78-83. PubMed ID: 11372759
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Apoptosis of erythroid precursors under stimulation with thrombopoietin: contribution to megakaryocytic lineage choice.
    Sawai N; Koike K; Ito S; Kurokawa Y; Mwamtemi HH; Kinoshita T; Sakashita K; Higuchi T; Takeuchi K; Shiohara M; Ogami K; Komiyama A
    Stem Cells; 1999; 17(1):45-53. PubMed ID: 10215401
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inducible expression of the megakaryocyte-specific gene glycoprotein IX is mediated through an Ets binding site and involves upstream activation of extracellular signal-regulated kinase.
    Eisbacher M; Khachigian LM; Khin TH; Holmes ML; Chong BH
    Cell Growth Differ; 2001 Aug; 12(8):435-45. PubMed ID: 11504709
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Proliferative properties of human umbilical cord blood megakaryocyte progenitor cells to human thrombopoietin.
    Hagiwara T; Kodama I; Horie K; Kato T; Miyazaki H
    Exp Hematol; 1998 Mar; 26(3):228-35. PubMed ID: 9502619
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Thrombopoietin-induced activation of the mitogen-activated protein kinase (MAPK) pathway in normal megakaryocytes: role in endomitosis.
    Rojnuckarin P; Drachman JG; Kaushansky K
    Blood; 1999 Aug; 94(4):1273-82. PubMed ID: 10438715
    [TBL] [Abstract][Full Text] [Related]  

  • 7. hNUDC promotes the cell proliferation and differentiation in a leukemic cell line via activation of the thrombopoietin receptor (Mpl).
    Tang YS; Zhang YP; Xu P
    Leukemia; 2008 May; 22(5):1018-25. PubMed ID: 18288130
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of TPO-induced MEK or mTOR activity induces opposite effects on the ploidy of human differentiating megakaryocytes.
    Guerriero R; Parolini I; Testa U; Samoggia P; Petrucci E; Sargiacomo M; Chelucci C; Gabbianelli M; Peschle C
    J Cell Sci; 2006 Feb; 119(Pt 4):744-52. PubMed ID: 16449323
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The alpha(IIb)beta(3) integrin and GPIb-V-IX complex identify distinct stages in the maturation of CD34(+) cord blood cells to megakaryocytes.
    Lepage A; Leboeuf M; Cazenave JP; de la Salle C; Lanza F; Uzan G
    Blood; 2000 Dec; 96(13):4169-77. PubMed ID: 11110688
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Flt3/Flk-2-ligand in synergy with thrombopoietin delays megakaryocyte development and increases the numbers of megakaryocyte progenitor cells in serum-free cultures initiated with CD34+ cells.
    Sigurjónsson OE; Gudmundsson KO; Haraldsdóttir V; Rafnar T; Gudmundsson S
    J Hematother Stem Cell Res; 2002 Apr; 11(2):389-400. PubMed ID: 11983110
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of recombinant human thrombopoietin alone and in combination with erythropoietin and early-acting cytokines on human mobilized purified CD34+ progenitor cells cultured in serum-depleted medium.
    Birkmann J; Oez S; Smetak M; Kaiser G; Kappauf H; Gallmeier WM
    Stem Cells; 1997; 15(1):18-32. PubMed ID: 9007219
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of erythroid differentiation and induction of megakaryocytic differentiation by thrombopoietin are regulated by two different mechanisms in TPO-dependent UT-7/c-mpl and TF-1/c-mpl cell lines.
    Goncalves F; Lacout C; Féger F; Cohen-Solal K; Guichard J; Cramer E; Vainchenker W; Duménil D
    Leukemia; 1998 Sep; 12(9):1355-66. PubMed ID: 9737683
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ex vivo expansion of megakaryocyte progenitor cells: cord blood versus mobilized peripheral blood.
    De Bruyn C; Delforge A; Martiat P; Bron D
    Stem Cells Dev; 2005 Aug; 14(4):415-24. PubMed ID: 16137231
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Thrombopoietin requires additional megakaryocyte-active cytokines for optimal ex vivo expansion of megakaryocyte precursor cells.
    Williams JL; Pipia GG; Datta NS; Long MW
    Blood; 1998 Jun; 91(11):4118-26. PubMed ID: 9596657
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Megakaryocyte growth and development factor-induced proliferation and differentiation are regulated by the mitogen-activated protein kinase pathway in primitive cord blood hematopoietic progenitors.
    Fichelson S; Freyssinier JM; Picard F; Fontenay-Roupie M; Guesnu M; Cherai M; Gisselbrecht S; Porteu F
    Blood; 1999 Sep; 94(5):1601-13. PubMed ID: 10477685
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Insights into the cellular mechanisms of erythropoietin-thrombopoietin synergy.
    Papayannopoulou T; Brice M; Farrer D; Kaushansky K
    Exp Hematol; 1996 Apr; 24(5):660-9. PubMed ID: 8605971
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Thrombopoietin is synergistic with other cytokines for expansion of cord blood progenitor cells.
    Won JH; Cho SD; Park SK; Lee GT; Baick SH; Suh WS; Hong DS; Park HS
    J Hematother Stem Cell Res; 2000 Aug; 9(4):465-73. PubMed ID: 10982244
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Thrombopoietin induces tyrosine phosphorylation and activation of mitogen-activated protein kinases in a human thrombopoietin-dependent cell line.
    Yamada M; Komatsu N; Okada K; Kato T; Miyazaki H; Miura Y
    Biochem Biophys Res Commun; 1995 Dec; 217(1):230-7. PubMed ID: 8526916
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Critical role for ERK1/2 in bone marrow and fetal liver-derived primary megakaryocyte differentiation, motility, and proplatelet formation.
    Mazharian A; Watson SP; Séverin S
    Exp Hematol; 2009 Oct; 37(10):1238-1249.e5. PubMed ID: 19619605
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Quantitative and qualitative differences in thrombopoietin-dependent hematopoietic progenitor development between cord blood and bone marrow.
    Mwamtemi HH; Higuchi T; Sawai N; Hidaka E; Koike K
    Transplantation; 2000 Apr; 69(8):1645-54. PubMed ID: 10836376
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.