BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

908 related articles for article (PubMed ID: 11453890)

  • 1. In vitro metabolism and drug interaction potential of a new highly potent anti-cytomegalovirus molecule, CMV423 (2-chloro 3-pyridine 3-yl 5,6,7,8-tetrahydroindolizine I-carboxamide).
    Bournique B; Lambert N; Boukaiba R; Martinet M
    Br J Clin Pharmacol; 2001 Jul; 52(1):53-63. PubMed ID: 11453890
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Kinetic characterization and identification of the enzymes responsible for the hepatic biotransformation of adinazolam and N-desmethyladinazolam in man.
    Venkatakrishnan K; von Moltke LL; Duan SX; Fleishaker JC; Shader RI; Greenblatt DJ
    J Pharm Pharmacol; 1998 Mar; 50(3):265-74. PubMed ID: 9600717
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Biotransformation of parathion in human liver: participation of CYP3A4 and its inactivation during microsomal parathion oxidation.
    Butler AM; Murray M
    J Pharmacol Exp Ther; 1997 Feb; 280(2):966-73. PubMed ID: 9023313
    [TBL] [Abstract][Full Text] [Related]  

  • 4. In vitro metabolism of the calmodulin antagonist DY-9760e (3-[2-[4-(3-chloro-2-methylphenyl)-1-piperazinyl]ethyl]-5,6-dimethoxy-1-(4-imidazolylmethyl)-1H-indazole dihydrochloride 3.5 hydrate) by human liver microsomes: involvement of cytochromes p450 in atypical kinetics and potential drug interactions.
    Tachibana S; Fujimaki Y; Yokoyama H; Okazaki O; Sudo K
    Drug Metab Dispos; 2005 Nov; 33(11):1628-36. PubMed ID: 16049129
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Identification of CYP3A4 as the predominant isoform responsible for the metabolism of ambroxol in human liver microsomes.
    Ishiguro N; Senda C; Kishimoto W; Sakai K; Funae Y; Igarashi T
    Xenobiotica; 2000 Jan; 30(1):71-80. PubMed ID: 10659952
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of human cytochrome P450 isoforms involved in the metabolism of S-2-[4-(3-methyl-2-thienyl)phenyl]propionic acid.
    Taguchi K; Konishi T; Nishikawa H; Kitamura S
    Xenobiotica; 1999 Sep; 29(9):899-907. PubMed ID: 10548450
    [TBL] [Abstract][Full Text] [Related]  

  • 7. In vitro effects of tacrolimus on human cytochrome P450.
    Lecointre K; Furlan V; Taburet AM
    Fundam Clin Pharmacol; 2002 Dec; 16(6):455-60. PubMed ID: 12685503
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Isoniazid is a mechanism-based inhibitor of cytochrome P450 1A2, 2A6, 2C19 and 3A4 isoforms in human liver microsomes.
    Wen X; Wang JS; Neuvonen PJ; Backman JT
    Eur J Clin Pharmacol; 2002 Jan; 57(11):799-804. PubMed ID: 11868802
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Metabolism of 7-benzyloxy-4-trifluoromethyl-coumarin by human hepatic cytochrome P450 isoforms.
    Renwick AB; Surry D; Price RJ; Lake BG; Evans DC
    Xenobiotica; 2000 Oct; 30(10):955-69. PubMed ID: 11315104
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The involvement of CYP1A2 and CYP3A4 in the metabolism of clozapine.
    Eiermann B; Engel G; Johansson I; Zanger UM; Bertilsson L
    Br J Clin Pharmacol; 1997 Nov; 44(5):439-46. PubMed ID: 9384460
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effects of arachidonic acid, prostaglandins, retinol, retinoic acid and cholecalciferol on xenobiotic oxidations catalysed by human cytochrome P450 enzymes.
    Yamazaki H; Shimada T
    Xenobiotica; 1999 Mar; 29(3):231-41. PubMed ID: 10219964
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Role of human hepatic cytochrome P450 1A2 and 3A4 in the metabolic activation of estrone.
    Shou M; Korzekwa KR; Brooks EN; Krausz KW; Gonzalez FJ; Gelboin HV
    Carcinogenesis; 1997 Jan; 18(1):207-14. PubMed ID: 9054608
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Gemfibrozil is a potent inhibitor of human cytochrome P450 2C9.
    Wen X; Wang JS; Backman JT; Kivistö KT; Neuvonen PJ
    Drug Metab Dispos; 2001 Nov; 29(11):1359-61. PubMed ID: 11602509
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nortriptyline E-10-hydroxylation in vitro is mediated by human CYP2D6 (high affinity) and CYP3A4 (low affinity): implications for interactions with enzyme-inducing drugs.
    Venkatakrishnan K; von Moltke LL; Greenblatt DJ
    J Clin Pharmacol; 1999 Jun; 39(6):567-77. PubMed ID: 10354960
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Effects of propofol on human hepatic microsomal cytochrome P450 activities.
    McKillop D; Wild MJ; Butters CJ; Simcock C
    Xenobiotica; 1998 Sep; 28(9):845-53. PubMed ID: 9764927
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Contribution of human cytochrome p-450 isoforms to the metabolism of the simplest phenothiazine neuroleptic promazine.
    Wójcikowski J; Pichard-Garcia L; Maurel P; Daniel WA
    Br J Pharmacol; 2003 Apr; 138(8):1465-74. PubMed ID: 12721102
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Human reductive halothane metabolism in vitro is catalyzed by cytochrome P450 2A6 and 3A4.
    Spracklin DK; Thummel KE; Kharasch ED
    Drug Metab Dispos; 1996 Sep; 24(9):976-83. PubMed ID: 8886607
    [TBL] [Abstract][Full Text] [Related]  

  • 18. In vitro metabolism of quinidine: the (3S)-3-hydroxylation of quinidine is a specific marker reaction for cytochrome P-4503A4 activity in human liver microsomes.
    Nielsen TL; Rasmussen BB; Flinois JP; Beaune P; Brosen K
    J Pharmacol Exp Ther; 1999 Apr; 289(1):31-7. PubMed ID: 10086984
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Relative contributions of the five major human cytochromes P450, 1A2, 2C9, 2C19, 2D6, and 3A4, to the hepatic metabolism of the proteasome inhibitor bortezomib.
    Uttamsingh V; Lu C; Miwa G; Gan LS
    Drug Metab Dispos; 2005 Nov; 33(11):1723-8. PubMed ID: 16103134
    [TBL] [Abstract][Full Text] [Related]  

  • 20.
    Zhang N; Liu J; Chen Z; Dou W
    Pharm Biol; 2019 Dec; 57(1):571-576. PubMed ID: 31456483
    [No Abstract]   [Full Text] [Related]  

    [Next]    [New Search]
    of 46.