These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
4. Structure and function of TolC: the bacterial exit duct for proteins and drugs. Koronakis V; Eswaran J; Hughes C Annu Rev Biochem; 2004; 73():467-89. PubMed ID: 15189150 [TBL] [Abstract][Full Text] [Related]
5. Channel-tunnels: outer membrane components of type I secretion systems and multidrug efflux pumps of Gram-negative bacteria. Andersen C Rev Physiol Biochem Pharmacol; 2003; 147():122-65. PubMed ID: 12783268 [TBL] [Abstract][Full Text] [Related]
6. Evaluation of a structural model of Pseudomonas aeruginosa outer membrane protein OprM, an efflux component involved in intrinsic antibiotic resistance. Wong KK; Brinkman FS; Benz RS; Hancock RE J Bacteriol; 2001 Jan; 183(1):367-74. PubMed ID: 11114937 [TBL] [Abstract][Full Text] [Related]
7. Substrate-triggered recruitment of the TolC channel-tunnel during type I export of hemolysin by Escherichia coli. Balakrishnan L; Hughes C; Koronakis V J Mol Biol; 2001 Oct; 313(3):501-10. PubMed ID: 11676535 [TBL] [Abstract][Full Text] [Related]
8. Crystal structure of the bacterial membrane protein TolC central to multidrug efflux and protein export. Koronakis V; Sharff A; Koronakis E; Luisi B; Hughes C Nature; 2000 Jun; 405(6789):914-9. PubMed ID: 10879525 [TBL] [Abstract][Full Text] [Related]
9. The role of the TolC family in protein transport and multidrug efflux. From stereochemical certainty to mechanistic hypothesis. Sharff A; Fanutti C; Shi J; Calladine C; Luisi B Eur J Biochem; 2001 Oct; 268(19):5011-26. PubMed ID: 11589692 [TBL] [Abstract][Full Text] [Related]
10. A periplasmic coiled-coil interface underlying TolC recruitment and the assembly of bacterial drug efflux pumps. Lobedanz S; Bokma E; Symmons MF; Koronakis E; Hughes C; Koronakis V Proc Natl Acad Sci U S A; 2007 Mar; 104(11):4612-7. PubMed ID: 17360572 [TBL] [Abstract][Full Text] [Related]
11. Transition to the open state of the TolC periplasmic tunnel entrance. Andersen C; Koronakis E; Bokma E; Eswaran J; Humphreys D; Hughes C; Koronakis V Proc Natl Acad Sci U S A; 2002 Aug; 99(17):11103-8. PubMed ID: 12163644 [TBL] [Abstract][Full Text] [Related]
12. An aspartate ring at the TolC tunnel entrance determines ion selectivity and presents a target for blocking by large cations. Andersen C; Koronakis E; Hughes C; Koronakis V Mol Microbiol; 2002 Jun; 44(5):1131-9. PubMed ID: 12068802 [TBL] [Abstract][Full Text] [Related]
14. Locking TolC entrance helices to prevent protein translocation by the bacterial type I export apparatus. Eswaran J; Hughes C; Koronakis V J Mol Biol; 2003 Mar; 327(2):309-15. PubMed ID: 12628238 [TBL] [Abstract][Full Text] [Related]
15. TolC--the bacterial exit duct for proteins and drugs. Koronakis V FEBS Lett; 2003 Nov; 555(1):66-71. PubMed ID: 14630321 [TBL] [Abstract][Full Text] [Related]
16. Type I secretion and multidrug efflux: transport through the TolC channel-tunnel. Buchanan SK Trends Biochem Sci; 2001 Jan; 26(1):3-6. PubMed ID: 11165499 [TBL] [Abstract][Full Text] [Related]
17. Structure of the ligand-blocked periplasmic entrance of the bacterial multidrug efflux protein TolC. Higgins MK; Eswaran J; Edwards P; Schertler GF; Hughes C; Koronakis V J Mol Biol; 2004 Sep; 342(3):697-702. PubMed ID: 15342230 [TBL] [Abstract][Full Text] [Related]
18. Directed evolution of a bacterial efflux pump: adaptation of the E. coli TolC exit duct to the Pseudomonas MexAB translocase. Bokma E; Koronakis E; Lobedanz S; Hughes C; Koronakis V FEBS Lett; 2006 Oct; 580(22):5339-43. PubMed ID: 16979625 [TBL] [Abstract][Full Text] [Related]
19. Computer simulations suggest direct and stable tip to tip interaction between the outer membrane channel TolC and the isolated docking domain of the multidrug RND efflux transporter AcrB. Schmidt TH; Raunest M; Fischer N; Reith D; Kandt C Biochim Biophys Acta; 2016 Jul; 1858(7 Pt A):1419-26. PubMed ID: 27045078 [TBL] [Abstract][Full Text] [Related]
20. Carboxy-terminal region involved in activity of Escherichia coli TolC. Yamanaka H; Izawa H; Okamoto K J Bacteriol; 2001 Dec; 183(23):6961-4. PubMed ID: 11698388 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]