These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

688 related articles for article (PubMed ID: 11454679)

  • 1. Repair of 8-oxodeoxyguanosine lesions in mitochondrial dna depends on the oxoguanine dna glycosylase (OGG1) gene and 8-oxoguanine accumulates in the mitochondrial dna of OGG1-defective mice.
    de Souza-Pinto NC; Eide L; Hogue BA; Thybo T; Stevnsner T; Seeberg E; Klungland A; Bohr VA
    Cancer Res; 2001 Jul; 61(14):5378-81. PubMed ID: 11454679
    [TBL] [Abstract][Full Text] [Related]  

  • 2. The basal levels of 8-oxoG and other oxidative modifications in intact mitochondrial DNA are low even in repair-deficient (Ogg1(-/-)/Csb(-/-)) mice.
    Trapp C; McCullough AK; Epe B
    Mutat Res; 2007 Dec; 625(1-2):155-63. PubMed ID: 17675188
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Age-dependent increase of 8-oxoguanine-, hypoxanthine-, and uracil- DNA glycosylase activities in liver extracts from OXYS rats with inherited overgeneration of free radicals and Wistar rats.
    Ishchenko A; Sinitsyna O; Krysanova Z; Vasyunina EA; Saparbaev M; Sidorkina O; Nevinsky GA
    Med Sci Monit; 2003 Jan; 9(1):BR16-24. PubMed ID: 12552232
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Cell proliferation in liver of Mmh/Ogg1-deficient mice enhances mutation frequency because of the presence of 8-hydroxyguanine in DNA.
    Arai T; Kelly VP; Komoro K; Minowa O; Noda T; Nishimura S
    Cancer Res; 2003 Jul; 63(14):4287-92. PubMed ID: 12874039
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mitochondrial repair of 8-oxoguanine is deficient in Cockayne syndrome group B.
    Stevnsner T; Nyaga S; de Souza-Pinto NC; van der Horst GT; Gorgels TG; Hogue BA; Thorslund T; Bohr VA
    Oncogene; 2002 Dec; 21(57):8675-82. PubMed ID: 12483520
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Expression of human oxoguanine glycosylase 1 or formamidopyrimidine glycosylase in human embryonic kidney 293 cells exacerbates methylmercury toxicity in vitro.
    Ondovcik SL; Preston TJ; McCallum GP; Wells PG
    Toxicol Appl Pharmacol; 2013 Aug; 271(1):41-8. PubMed ID: 23607987
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Activity of OGG1 variants in the repair of pro-oxidant-induced 8-oxo-2'-deoxyguanosine.
    Smart DJ; Chipman JK; Hodges NJ
    DNA Repair (Amst); 2006 Nov; 5(11):1337-45. PubMed ID: 16861056
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The C-terminal alphaO helix of human Ogg1 is essential for 8-oxoguanine DNA glycosylase activity: the mitochondrial beta-Ogg1 lacks this domain and does not have glycosylase activity.
    Hashiguchi K; Stuart JA; de Souza-Pinto NC; Bohr VA
    Nucleic Acids Res; 2004; 32(18):5596-608. PubMed ID: 15494448
    [TBL] [Abstract][Full Text] [Related]  

  • 9. DNA repair and aging in mouse liver: 8-oxodG glycosylase activity increase in mitochondrial but not in nuclear extracts.
    de Souza-Pinto NC; Hogue BA; Bohr VA
    Free Radic Biol Med; 2001 Apr; 30(8):916-23. PubMed ID: 11295534
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Mmh/Ogg1 gene inactivation results in accumulation of 8-hydroxyguanine in mice.
    Minowa O; Arai T; Hirano M; Monden Y; Nakai S; Fukuda M; Itoh M; Takano H; Hippou Y; Aburatani H; Masumura K; Nohmi T; Nishimura S; Noda T
    Proc Natl Acad Sci U S A; 2000 Apr; 97(8):4156-61. PubMed ID: 10725358
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The human OGG1 gene: structure, functions, and its implication in the process of carcinogenesis.
    Boiteux S; Radicella JP
    Arch Biochem Biophys; 2000 May; 377(1):1-8. PubMed ID: 10775435
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Retrovirus-mediated expression of the base excision repair proteins, formamidopyrimidine DNA glycosylase or human oxoguanine DNA glycosylase, protects hematopoietic cells from N,N',N"-triethylenethiophosphoramide (thioTEPA)-induced toxicity in vitro and in vivo.
    Kobune M; Xu Y; Baum C; Kelley MR; Williams DA
    Cancer Res; 2001 Jul; 61(13):5116-25. PubMed ID: 11431349
    [TBL] [Abstract][Full Text] [Related]  

  • 13. A global DNA repair mechanism involving the Cockayne syndrome B (CSB) gene product can prevent the in vivo accumulation of endogenous oxidative DNA base damage.
    Osterod M; Larsen E; Le Page F; Hengstler JG; Van Der Horst GT; Boiteux S; Klungland A; Epe B
    Oncogene; 2002 Nov; 21(54):8232-9. PubMed ID: 12447686
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Repair of oxidative damage in mitochondrial DNA of Saccharomyces cerevisiae: involvement of the MSH1-dependent pathway.
    Dzierzbicki P; Koprowski P; Fikus MU; Malc E; Ciesla Z
    DNA Repair (Amst); 2004 Apr; 3(4):403-11. PubMed ID: 15010316
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Different organization of base excision repair of uracil in DNA in nuclei and mitochondria and selective upregulation of mitochondrial uracil-DNA glycosylase after oxidative stress.
    Akbari M; Otterlei M; Peña-Diaz J; Krokan HE
    Neuroscience; 2007 Apr; 145(4):1201-12. PubMed ID: 17101234
    [TBL] [Abstract][Full Text] [Related]  

  • 16. No evidence of mitochondrial respiratory dysfunction in OGG1-null mice deficient in removal of 8-oxodeoxyguanine from mitochondrial DNA.
    Stuart JA; Bourque BM; de Souza-Pinto NC; Bohr VA
    Free Radic Biol Med; 2005 Mar; 38(6):737-45. PubMed ID: 15721984
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Defective repair of 8-hydroxyguanine in mitochondria of MCF-7 and MDA-MB-468 human breast cancer cell lines.
    Mambo E; Nyaga SG; Bohr VA; Evans MK
    Cancer Res; 2002 Mar; 62(5):1349-55. PubMed ID: 11888904
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Targeting human 8-oxoguanine glycosylase to mitochondria of oligodendrocytes protects against menadione-induced oxidative stress.
    Druzhyna NM; Hollensworth SB; Kelley MR; Wilson GL; Ledoux SP
    Glia; 2003 Jun; 42(4):370-8. PubMed ID: 12730957
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Spontaneous mutation, oxidative DNA damage, and the roles of base and nucleotide excision repair in the yeast Saccharomyces cerevisiae.
    Scott AD; Neishabury M; Jones DH; Reed SH; Boiteux S; Waters R
    Yeast; 1999 Feb; 15(3):205-18. PubMed ID: 10077187
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Msh1p counteracts oxidative lesion-induced instability of mtDNA and stimulates mitochondrial recombination in Saccharomyces cerevisiae.
    Kaniak A; Dzierzbicki P; Rogowska AT; Malc E; Fikus M; Ciesla Z
    DNA Repair (Amst); 2009 Mar; 8(3):318-29. PubMed ID: 19056520
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 35.