BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

201 related articles for article (PubMed ID: 11454694)

  • 1. 8-chloro-cAMP and 8-chloro-adenosine act by the same mechanism in multiple myeloma cells.
    Gandhi V; Ayres M; Halgren RG; Krett NL; Newman RA; Rosen ST
    Cancer Res; 2001 Jul; 61(14):5474-9. PubMed ID: 11454694
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Plasma and cellular pharmacology of 8-chloro-adenosine in mice and rats.
    Gandhi V; Chen W; Ayres M; Rhie JK; Madden TL; Newman RA
    Cancer Chemother Pharmacol; 2002 Aug; 50(2):85-94. PubMed ID: 12172971
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Protein kinase A-independent inhibition of proliferation and induction of apoptosis in human thyroid cancer cells by 8-Cl-adenosine.
    Robinson-White AJ; Hsiao HP; Leitner WW; Greene E; Bauer A; Krett NL; Nesterova M; Stratakis CA
    J Clin Endocrinol Metab; 2008 Mar; 93(3):1020-9. PubMed ID: 18073299
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Anti-proliferative effects of 8-chloro-cAMP and other cAMP analogs are unrelated to their effects on protein kinase A regulatory subunit expression.
    Lamb D; Steinberg RA
    J Cell Physiol; 2002 Aug; 192(2):216-24. PubMed ID: 12115728
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 8-Chloroadenosine mediates 8-chloro-cyclic AMP-induced down-regulation of cyclic AMP-dependent protein kinase in normal and neoplastic mouse lung epithelial cells by a cyclic AMP-independent mechanism.
    Lange-Carter CA; Vuillequez JJ; Malkinson AM
    Cancer Res; 1993 Jan; 53(2):393-400. PubMed ID: 8380255
    [TBL] [Abstract][Full Text] [Related]  

  • 6. RNA-directed actions of 8-chloro-adenosine in multiple myeloma cells.
    Stellrecht CM; Rodriguez CO; Ayres M; Gandhi V
    Cancer Res; 2003 Nov; 63(22):7968-74. PubMed ID: 14633728
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Inhibition of topoisomerase II by 8-chloro-adenosine triphosphate induces DNA double-stranded breaks in 8-chloro-adenosine-exposed human myelocytic leukemia K562 cells.
    Yang SY; Jia XZ; Feng LY; Li SY; An GS; Ni JH; Jia HT
    Biochem Pharmacol; 2009 Feb; 77(3):433-43. PubMed ID: 19014910
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Genome-wide expression profiling of 8-chloroadenosine- and 8-chloro-cAMP-treated human neuroblastoma cells using radioactive human cDNA microarray.
    Park GH; Choe J; Choo HJ; Park YG; Sohn J; Kim MK
    Exp Mol Med; 2002 Jul; 34(3):184-93. PubMed ID: 12216110
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Intracellular succinylation of 8-chloroadenosine and its effect on fumarate levels.
    Dennison JB; Ayres ML; Kaluarachchi K; Plunkett W; Gandhi V
    J Biol Chem; 2010 Mar; 285(11):8022-30. PubMed ID: 20064937
    [TBL] [Abstract][Full Text] [Related]  

  • 10. 8-Cl-adenosine is an active metabolite of 8-Cl-cAMP responsible for its in vitro antiproliferative effects on CHO mutants hypersensitive to cytostatic drugs.
    Robbins SK; Houlbrook S; Priddle JD; Harris AL
    Cancer Chemother Pharmacol; 2001 Dec; 48(6):451-8. PubMed ID: 11800025
    [TBL] [Abstract][Full Text] [Related]  

  • 11. 8-Cl-cAMP and its metabolite, 8-Cl-adenosine induce growth inhibition in mouse fibroblast DT cells through the same pathways: protein kinase C activation and cyclin B down-regulation.
    Ahn YH; Jung JM; Hong SH
    J Cell Physiol; 2004 Nov; 201(2):277-85. PubMed ID: 15334662
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Effects of 8-chloro-cyclic adenosine monophosphate on the growth and sensitivity to doxorubicin of multidrug-resistant tumour cell lines.
    Borsellino N; Crescimanno M; Leonardi V; D'Alessandro N
    Pharmacol Res; 1994 Jul; 30(1):81-90. PubMed ID: 7831198
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The antiproliferative effect of 8-chloro-adenosine, an active metabolite of 8-chloro-cyclic adenosine monophosphate, and disturbances in nucleic acid synthesis and cell cycle kinetics.
    Langeveld CH; Jongenelen CA; Theeuwes JW; Baak JP; Heimans JJ; Stoof JC; Peters GJ
    Biochem Pharmacol; 1997 Jan; 53(2):141-8. PubMed ID: 9037246
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Inhibition of colon tumor cell growth by 8-chloro-cAMP is dependent upon its conversion to 8-chloro-adenosine.
    Taylor CW; Yeoman LC
    Anticancer Drugs; 1992 Oct; 3(5):485-91. PubMed ID: 1450443
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Proliferation of nontransformed cells is inhibited by adenosine metabolite of but not by parental 8-Cl-cyclic AMP.
    Han Z; Chatterjee D; Wyche JH
    J Pharmacol Exp Ther; 1993 May; 265(2):790-4. PubMed ID: 8388460
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Ex vivo cytotoxic drug evaluation by DiSC assay to expedite identification of clinical targets: results with 8-chloro-cAMP.
    Bosanquet AG; Burlton AR; Bell PB; Harris AL
    Br J Cancer; 1997; 76(4):511-8. PubMed ID: 9275029
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 8Cl-cAMP cytotoxicity in both steroid sensitive and insensitive multiple myeloma cell lines is mediated by 8Cl-adenosine.
    Halgren RG; Traynor AE; Pillay S; Zell JL; Heller KF; Krett NL; Rosen ST
    Blood; 1998 Oct; 92(8):2893-8. PubMed ID: 9763575
    [TBL] [Abstract][Full Text] [Related]  

  • 18. 8-Chloro-cyclic AMP-induced growth inhibition and apoptosis is mediated by p38 mitogen-activated protein kinase activation in HL60 cells.
    Ahn YH; Jung JM; Hong SH
    Cancer Res; 2005 Jun; 65(11):4896-901. PubMed ID: 15930311
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of CHK1 kinase by Gö6976 converts 8-chloro-adenosine-induced G2/M arrest into S arrest in human myelocytic leukemia K562 cells.
    Jia XZ; Yang SY; Zhou J; Li SY; Ni JH; An GS; Jia HT
    Biochem Pharmacol; 2009 Mar; 77(5):770-80. PubMed ID: 19059218
    [TBL] [Abstract][Full Text] [Related]  

  • 20. 2-Fluoroadenosine 3':5'-monophosphate. A metabolite of 2-fluoroadenosine in mouse cytotoxic lymphocytes.
    Zimmerman TP; Rideout JL; Wolberg G; Duncan GS; Elion GB
    J Biol Chem; 1976 Nov; 251(21):6757-66. PubMed ID: 185217
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.