These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

572 related articles for article (PubMed ID: 11454711)

  • 1. Telomerase inhibition in RenCa, a murine tumor cell line with short telomeres, by overexpression of a dominant negative mTERT mutant, reveals fundamental differences in telomerase regulation between human and murine cells.
    Sachsinger J; González-Suárez E; Samper E; Heicappell R; Müller M; Blasco MA
    Cancer Res; 2001 Jul; 61(14):5580-6. PubMed ID: 11454711
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Telomerase inhibition in a mouse cell line with long telomeres leads to rapid telomerase reactivation.
    Marie-Egyptienne DT; Brault ME; Zhu S; Autexier C
    Exp Cell Res; 2008 Feb; 314(3):668-75. PubMed ID: 18067891
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Telomere dysfunction and telomerase reactivation in human leukemia cell lines after telomerase inhibition by the expression of a dominant-negative hTERT mutant.
    Delhommeau F; Thierry A; Feneux D; Lauret E; Leclercq E; Courtier MH; Sainteny F; Vainchenker W; Bennaceur-Griscelli A
    Oncogene; 2002 Nov; 21(54):8262-71. PubMed ID: 12447689
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Telomeric function of mammalian telomerases at short telomeres.
    Fakhoury J; Marie-Egyptienne DT; Londoño-Vallejo JA; Autexier C
    J Cell Sci; 2010 May; 123(Pt 10):1693-704. PubMed ID: 20427319
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mass cultured human fibroblasts overexpressing hTERT encounter a growth crisis following an extended period of proliferation.
    MacKenzie KL; Franco S; May C; Sadelain M; Moore MA
    Exp Cell Res; 2000 Sep; 259(2):336-50. PubMed ID: 10964501
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Telomere dynamics in cells with introduced telomerase: a rapid assay for telomerase activity on telomeres.
    McChesney PA; Aisner DL; Frank BC; Wright WE; Shay JW
    Mol Cell Biol Res Commun; 2000 May; 3(5):312-8. PubMed ID: 10964756
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Growth defects in mouse telomerase RNA-deficient cells expressing a template-mutated mouse telomerase RNA.
    Marie-Egyptienne DT; Brault ME; Nimmo GA; Londoño-Vallejo JA; Autexier C
    Cancer Lett; 2009 Mar; 275(2):266-76. PubMed ID: 19056167
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Induced senescence in HeLa cervical carcinoma cells containing elevated telomerase activity and extended telomeres.
    Goodwin EC; DiMaio D
    Cell Growth Differ; 2001 Nov; 12(11):525-34. PubMed ID: 11714633
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Telomerase- and alternative telomere lengthening-independent telomere stabilization in a metastasis-derived human non-small cell lung cancer cell line: effect of ectopic hTERT.
    Brachner A; Sasgary S; Pirker C; Rodgarkia C; Mikula M; Mikulits W; Bergmeister H; Setinek U; Wieser M; Chin SF; Caldas C; Micksche M; Cerni C; Berger W
    Cancer Res; 2006 Apr; 66(7):3584-92. PubMed ID: 16585183
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ribozyme-mediated telomerase inhibition induces immediate cell loss but not telomere shortening in ovarian cancer cells.
    Saretzki G; Ludwig A; von Zglinicki T; Runnebaum IB
    Cancer Gene Ther; 2001 Oct; 8(10):827-34. PubMed ID: 11687906
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Inhibition of human telomerase enhances the effect of the tyrosine kinase inhibitor, imatinib, in BCR-ABL-positive leukemia cells.
    Tauchi T; Nakajima A; Sashida G; Shimamoto T; Ohyashiki JH; Abe K; Yamamoto K; Ohyashiki K
    Clin Cancer Res; 2002 Nov; 8(11):3341-7. PubMed ID: 12429620
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Inhibition of telomerase limits the growth of human cancer cells.
    Hahn WC; Stewart SA; Brooks MW; York SG; Eaton E; Kurachi A; Beijersbergen RL; Knoll JH; Meyerson M; Weinberg RA
    Nat Med; 1999 Oct; 5(10):1164-70. PubMed ID: 10502820
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Telomerase inhibition by an siRNA directed against hTERT leads to telomere attrition in HT29 cells.
    de Souza Nascimento P; Alves G; Fiedler W
    Oncol Rep; 2006 Aug; 16(2):423-8. PubMed ID: 16820926
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Telomerase activity level, but not hTERT mRNA and hTR level, regulates telomere length in telomerase-reconstituted primary fibroblasts.
    Swiggers SJ; Nibbeling HA; Zeilemaker A; Kuijpers MA; Mattern KA; Zijlmans JM
    Exp Cell Res; 2004 Jul; 297(2):434-43. PubMed ID: 15212946
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Regulation of human telomerase activity: repression by normal chromosome 3 abolishes nuclear telomerase reverse transcriptase transcripts but does not affect c-Myc activity.
    Ducrest AL; Amacker M; Mathieu YD; Cuthbert AP; Trott DA; Newbold RF; Nabholz M; Lingner J
    Cancer Res; 2001 Oct; 61(20):7594-602. PubMed ID: 11606399
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Expression of mTert in primary murine cells links the growth-promoting effects of telomerase to transforming growth factor-beta signaling.
    Geserick C; Tejera A; González-Suárez E; Klatt P; Blasco MA
    Oncogene; 2006 Jul; 25(31):4310-9. PubMed ID: 16501597
    [TBL] [Abstract][Full Text] [Related]  

  • 17. hTERT associates with human telomeres and enhances genomic stability and DNA repair.
    Sharma GG; Gupta A; Wang H; Scherthan H; Dhar S; Gandhi V; Iliakis G; Shay JW; Young CS; Pandita TK
    Oncogene; 2003 Jan; 22(1):131-46. PubMed ID: 12527915
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ectopic mTERT expression in mouse embryonic stem cells does not affect differentiation but confers resistance to differentiation- and stress-induced p53-dependent apoptosis.
    Lee MK; Hande MP; Sabapathy K
    J Cell Sci; 2005 Feb; 118(Pt 4):819-29. PubMed ID: 15687103
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Assembly of mutant-template telomerase RNA into catalytically active telomerase ribonucleoprotein that can act on telomeres is required for apoptosis and cell cycle arrest in human cancer cells.
    Goldkorn A; Blackburn EH
    Cancer Res; 2006 Jun; 66(11):5763-71. PubMed ID: 16740715
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Retinoids down-regulate telomerase and telomere length in a pathway distinct from leukemia cell differentiation.
    Pendino F; Flexor M; Delhommeau F; Buet D; Lanotte M; Segal-Bendirdjian E
    Proc Natl Acad Sci U S A; 2001 Jun; 98(12):6662-7. PubMed ID: 11371621
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 29.