These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

190 related articles for article (PubMed ID: 11454728)

  • 1. Escitalopram (S-citalopram) and its metabolites in vitro: cytochromes mediating biotransformation, inhibitory effects, and comparison to R-citalopram.
    von Moltke LL; Greenblatt DJ; Giancarlo GM; Granda BW; Harmatz JS; Shader RI
    Drug Metab Dispos; 2001 Aug; 29(8):1102-9. PubMed ID: 11454728
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Citalopram and desmethylcitalopram in vitro: human cytochromes mediating transformation, and cytochrome inhibitory effects.
    von Moltke LL; Greenblatt DJ; Grassi JM; Granda BW; Venkatakrishnan K; Duan SX; Fogelman SM; Harmatz JS; Shader RI
    Biol Psychiatry; 1999 Sep; 46(6):839-49. PubMed ID: 10494454
    [TBL] [Abstract][Full Text] [Related]  

  • 3. O- and N-demethylation of venlafaxine in vitro by human liver microsomes and by microsomes from cDNA-transfected cells: effect of metabolic inhibitors and SSRI antidepressants.
    Fogelman SM; Schmider J; Venkatakrishnan K; von Moltke LL; Harmatz JS; Shader RI; Greenblatt DJ
    Neuropsychopharmacology; 1999 May; 20(5):480-90. PubMed ID: 10192828
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Identification of three cytochrome P450 isozymes involved in N-demethylation of citalopram enantiomers in human liver microsomes.
    Rochat B; Amey M; Gillet M; Meyer UA; Baumann P
    Pharmacogenetics; 1997 Feb; 7(1):1-10. PubMed ID: 9110356
    [TBL] [Abstract][Full Text] [Related]  

  • 5. In vitro biotransformation of sildenafil (Viagra): identification of human cytochromes and potential drug interactions.
    Warrington JS; Shader RI; von Moltke LL; Greenblatt DJ
    Drug Metab Dispos; 2000 Apr; 28(4):392-7. PubMed ID: 10725306
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Multiple human cytochromes contribute to biotransformation of dextromethorphan in-vitro: role of CYP2C9, CYP2C19, CYP2D6, and CYP3A.
    von Moltke LL; Greenblatt DJ; Grassi JM; Granda BW; Venkatakrishnan K; Schmider J; Harmatz JS; Shader RI
    J Pharm Pharmacol; 1998 Sep; 50(9):997-1004. PubMed ID: 9811160
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Kinetic characterization and identification of the enzymes responsible for the hepatic biotransformation of adinazolam and N-desmethyladinazolam in man.
    Venkatakrishnan K; von Moltke LL; Duan SX; Fleishaker JC; Shader RI; Greenblatt DJ
    J Pharm Pharmacol; 1998 Mar; 50(3):265-74. PubMed ID: 9600717
    [TBL] [Abstract][Full Text] [Related]  

  • 8. CYP3A4 is the major CYP isoform mediating the in vitro hydroxylation and demethylation of flunitrazepam.
    Hesse LM; Venkatakrishnan K; von Moltke LL; Shader RI; Greenblatt DJ
    Drug Metab Dispos; 2001 Feb; 29(2):133-40. PubMed ID: 11159802
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Metabolism of 7-benzyloxy-4-trifluoromethyl-coumarin by human hepatic cytochrome P450 isoforms.
    Renwick AB; Surry D; Price RJ; Lake BG; Evans DC
    Xenobiotica; 2000 Oct; 30(10):955-69. PubMed ID: 11315104
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Citalopram and escitalopram plasma drug and metabolite concentrations: genome-wide associations.
    Ji Y; Schaid DJ; Desta Z; Kubo M; Batzler AJ; Snyder K; Mushiroda T; Kamatani N; Ogburn E; Hall-Flavin D; Flockhart D; Nakamura Y; Mrazek DA; Weinshilboum RM
    Br J Clin Pharmacol; 2014 Aug; 78(2):373-83. PubMed ID: 24528284
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Human cytochromes mediating N-demethylation of fluoxetine in vitro.
    von Moltke LL; Greenblatt DJ; Duan SX; Schmider J; Wright CE; Harmatz JS; Shader RI
    Psychopharmacology (Berl); 1997 Aug; 132(4):402-7. PubMed ID: 9298519
    [TBL] [Abstract][Full Text] [Related]  

  • 12. (R)-, (S)-, and racemic fluoxetine N-demethylation by human cytochrome P450 enzymes.
    Margolis JM; O'Donnell JP; Mankowski DC; Ekins S; Obach RS
    Drug Metab Dispos; 2000 Oct; 28(10):1187-91. PubMed ID: 10997938
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Effect of selective serotonin reuptake inhibitors on the oxidative metabolism of propafenone: in vitro studies using human liver microsomes.
    Hemeryck A; De Vriendt C; Belpaire FM
    J Clin Psychopharmacol; 2000 Aug; 20(4):428-34. PubMed ID: 10917404
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The clinical pharmacokinetics of escitalopram.
    Rao N
    Clin Pharmacokinet; 2007; 46(4):281-90. PubMed ID: 17375980
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Metabolism of citalopram enantiomers in CYP2C19/CYP2D6 phenotyped panels of healthy Swedes.
    Herrlin K; Yasui-Furukori N; Tybring G; Widén J; Gustafsson LL; Bertilsson L
    Br J Clin Pharmacol; 2003 Oct; 56(4):415-21. PubMed ID: 12968986
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Allosteric modulation of the effect of escitalopram, paroxetine and fluoxetine: in-vitro and in-vivo studies.
    Mansari ME; Wiborg O; Mnie-Filali O; Benturquia N; Sánchez C; Haddjeri N
    Int J Neuropsychopharmacol; 2007 Feb; 10(1):31-40. PubMed ID: 16448580
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The gastroprokinetic and antiemetic drug metoclopramide is a substrate and inhibitor of cytochrome P450 2D6.
    Desta Z; Wu GM; Morocho AM; Flockhart DA
    Drug Metab Dispos; 2002 Mar; 30(3):336-43. PubMed ID: 11854155
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Enantiospecific effects of chiral drugs on cytochrome P450 inhibition in vitro.
    Krasulova K; Siller M; Holas O; Dvorak Z; Anzenbacher P
    Xenobiotica; 2016; 46(4):315-24. PubMed ID: 26338061
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Nortriptyline E-10-hydroxylation in vitro is mediated by human CYP2D6 (high affinity) and CYP3A4 (low affinity): implications for interactions with enzyme-inducing drugs.
    Venkatakrishnan K; von Moltke LL; Greenblatt DJ
    J Clin Pharmacol; 1999 Jun; 39(6):567-77. PubMed ID: 10354960
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Azelastine N-demethylation by cytochrome P-450 (CYP)3A4, CYP2D6, and CYP1A2 in human liver microsomes: evaluation of approach to predict the contribution of multiple CYPs.
    Nakajima M; Nakamura S; Tokudome S; Shimada N; Yamazaki H; Yokoi T
    Drug Metab Dispos; 1999 Dec; 27(12):1381-91. PubMed ID: 10570018
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.