BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

208 related articles for article (PubMed ID: 11455016)

  • 1. Selective potentiation of paclitaxel (taxol)-induced cell death by mitogen-activated protein kinase kinase inhibition in human cancer cell lines.
    McDaid HM; Horwitz SB
    Mol Pharmacol; 2001 Aug; 60(2):290-301. PubMed ID: 11455016
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of mitogen-activated protein kinase/extracellular signal-regulated kinase kinase enhances chemotherapeutic effects on H460 human non-small cell lung cancer cells through activation of apoptosis.
    Hu Y; Bally M; Dragowska WH; Mayer L
    Mol Cancer Ther; 2003 Jul; 2(7):641-9. PubMed ID: 12883037
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Sequence-dependent potentiation of paclitaxel-mediated apoptosis in human leukemia cells by inhibitors of the mitogen-activated protein kinase kinase/mitogen-activated protein kinase pathway.
    Yu C; Wang S; Dent P; Grant S
    Mol Pharmacol; 2001 Jul; 60(1):143-54. PubMed ID: 11408609
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Paclitaxel induces prolonged activation of the Ras/MEK/ERK pathway independently of activating the programmed cell death machinery.
    Okano J ; Rustgi AK
    J Biol Chem; 2001 Jun; 276(22):19555-64. PubMed ID: 11278851
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Glucocorticoid receptor-induced MAPK phosphatase-1 (MPK-1) expression inhibits paclitaxel-associated MAPK activation and contributes to breast cancer cell survival.
    Wu W; Pew T; Zou M; Pang D; Conzen SD
    J Biol Chem; 2005 Feb; 280(6):4117-24. PubMed ID: 15590693
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Inhibition of extracellular signal-regulated kinase (ERK) mediates cell cycle phase independent apoptosis in vinblastine-treated ML-1 cells.
    Stadheim TA; Xiao H; Eastman A
    Cancer Res; 2001 Feb; 61(4):1533-40. PubMed ID: 11245462
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Distinct mechanisms of taxol-induced serine phosphorylation of the 66-kDa Shc isoform in A549 and RAW 264.7 cells.
    Yang CP; Horwitz SB
    Biochim Biophys Acta; 2002 Jun; 1590(1-3):76-83. PubMed ID: 12063170
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inactivation of the antiapoptotic phosphatidylinositol 3-kinase-Akt pathway by the combined treatment of taxol and mitogen-activated protein kinase kinase inhibition.
    MacKeigan JP; Taxman DJ; Hunter D; Earp HS; Graves LM; Ting JP
    Clin Cancer Res; 2002 Jul; 8(7):2091-9. PubMed ID: 12114408
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Involvement of Asp-Glu-Val-Asp-directed, caspase-mediated mitogen-activated protein kinase kinase 1 Cleavage, c-Jun N-terminal kinase activation, and subsequent Bcl-2 phosphorylation for paclitaxel-induced apoptosis in HL-60 cells.
    Shiah SG; Chuang SE; Kuo ML
    Mol Pharmacol; 2001 Feb; 59(2):254-62. PubMed ID: 11160861
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Glutamate induces phosphorylation of Elk-1 and CREB, along with c-fos activation, via an extracellular signal-regulated kinase-dependent pathway in brain slices.
    Vanhoutte P; Barnier JV; Guibert B; Pagès C; Besson MJ; Hipskind RA; Caboche J
    Mol Cell Biol; 1999 Jan; 19(1):136-46. PubMed ID: 9858538
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Activation of extracellular signal-regulated kinase and c-Jun-NH(2)-terminal kinase but not p38 mitogen-activated protein kinases is required for RRR-alpha-tocopheryl succinate-induced apoptosis of human breast cancer cells.
    Yu W; Liao QY; Hantash FM; Sanders BG; Kline K
    Cancer Res; 2001 Sep; 61(17):6569-76. PubMed ID: 11522656
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Circadian and photic regulation of phosphorylation of ERK1/2 and Elk-1 in the suprachiasmatic nuclei of the Syrian hamster.
    Coogan AN; Piggins HD
    J Neurosci; 2003 Apr; 23(7):3085-93. PubMed ID: 12684495
    [TBL] [Abstract][Full Text] [Related]  

  • 13. MEK inhibition enhances paclitaxel-induced tumor apoptosis.
    MacKeigan JP; Collins TS; Ting JP
    J Biol Chem; 2000 Dec; 275(50):38953-6. PubMed ID: 11038347
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mitogen-activated protein kinase pathway is dispensable for microtubule-active drug-induced Raf-1/Bcl-2 phosphorylation and apoptosis in leukemia cells.
    Blagosklonny MV; Chuman Y; Bergan RC; Fojo T
    Leukemia; 1999 Jul; 13(7):1028-36. PubMed ID: 10400418
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Microtubule inhibitors elicit differential effects on MAP kinase (JNK, ERK, and p38) signaling pathways in human KB-3 carcinoma cells.
    Stone AA; Chambers TC
    Exp Cell Res; 2000 Jan; 254(1):110-9. PubMed ID: 10623471
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Differential expression of active, phosphorylation-dependent MAP kinases, MAPK/ERK, SAPK/JNK and p38, and specific transcription factor substrates following quinolinic acid excitotoxicity in the rat.
    Ferrer I; Blanco R; Carmona M
    Brain Res Mol Brain Res; 2001 Oct; 94(1-2):48-58. PubMed ID: 11597764
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Taxol induces apoptosis in cortical neurons by a mechanism independent of Bcl-2 phosphorylation.
    Figueroa-Masot XA; Hetman M; Higgins MJ; Kokot N; Xia Z
    J Neurosci; 2001 Jul; 21(13):4657-67. PubMed ID: 11425893
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Growth hormone stimulates phosphorylation and activation of elk-1 and expression of c-fos, egr-1, and junB through activation of extracellular signal-regulated kinases 1 and 2.
    Hodge C; Liao J; Stofega M; Guan K; Carter-Su C; Schwartz J
    J Biol Chem; 1998 Nov; 273(47):31327-36. PubMed ID: 9813041
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Synergistic induction of apoptosis in human leukemia cells (U937) exposed to bryostatin 1 and the proteasome inhibitor lactacystin involves dysregulation of the PKC/MAPK cascade.
    Vrana JA; Grant S
    Blood; 2001 Apr; 97(7):2105-14. PubMed ID: 11264178
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Serine protease inhibitor TPCK prevents Taxol-induced cell death and blocks c-Raf-1 and Bcl-2 phosphorylation in human breast carcinoma cells.
    Huang Y; Sheikh MS; Fornace AJ; Holbrook NJ
    Oncogene; 1999 Jun; 18(23):3431-9. PubMed ID: 10376521
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 11.