BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

678 related articles for article (PubMed ID: 11458985)

  • 1. Kinetics of testosterone 6beta-hydroxylation in the reconstituted system with similar ratios of purified CYP3A4, NADPH-cytochrome p450 oxidoreductase and cytochrome B5 to human liver microsomes.
    Taguchi M; Imaoka S; Yoshii K; Kobayashi K; Hosokawa M; Shimada N; Funae Y; Chiba K
    Res Commun Mol Pathol Pharmacol; 2001 Jul; 109(1-2):53-63. PubMed ID: 11458985
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Molecular characterization of specifically active recombinant fused enzymes consisting of CYP3A4, NADPH-cytochrome P450 oxidoreductase, and cytochrome b5.
    Inui H; Maeda A; Ohkawa H
    Biochemistry; 2007 Sep; 46(35):10213-21. PubMed ID: 17691855
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Coexpression of genetically engineered fused enzyme between yeast NADPH-P450 reductase and human cytochrome P450 3A4 and human cytochrome b5 in yeast.
    Hayashi K; Sakaki T; Kominami S; Inouye K; Yabusaki Y
    Arch Biochem Biophys; 2000 Sep; 381(1):164-70. PubMed ID: 11019832
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Enhancement of cytochrome P-450 3A4 catalytic activities by cytochrome b(5) in bacterial membranes.
    Yamazaki H; Nakajima M; Nakamura M; Asahi S; Shimada N; Gillam EM; Guengerich FP; Shimada T; Yokoi T
    Drug Metab Dispos; 1999 Sep; 27(9):999-1004. PubMed ID: 10460798
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Reconstitution of testosterone oxidation by purified rat cytochrome P450p (IIIA1).
    Halvorson M; Greenway D; Eberhart D; Fitzgerald K; Parkinson A
    Arch Biochem Biophys; 1990 Feb; 277(1):166-80. PubMed ID: 2106291
    [TBL] [Abstract][Full Text] [Related]  

  • 6. CYP3A4 expressed by insect cells infected with a recombinant baculovirus containing both CYP3A4 and human NADPH-cytochrome P450 reductase is catalytically similar to human liver microsomal CYP3A4.
    Lee CA; Kadwell SH; Kost TA; Serabjit-Singh CJ
    Arch Biochem Biophys; 1995 May; 319(1):157-67. PubMed ID: 7771780
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Lack of electron transfer from cytochrome b5 in stimulation of catalytic activities of cytochrome P450 3A4. Characterization of a reconstituted cytochrome P450 3A4/NADPH-cytochrome P450 reductase system and studies with apo-cytochrome b5.
    Yamazaki H; Johnson WW; Ueng YF; Shimada T; Guengerich FP
    J Biol Chem; 1996 Nov; 271(44):27438-44. PubMed ID: 8910324
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Reconstitution premixes for assays using purified recombinant human cytochrome P450, NADPH-cytochrome P450 reductase, and cytochrome b5.
    Shaw PM; Hosea NA; Thompson DV; Lenius JM; Guengerich FP
    Arch Biochem Biophys; 1997 Dec; 348(1):107-15. PubMed ID: 9390180
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Roles of cytochrome b5 in the oxidation of testosterone and nifedipine by recombinant cytochrome P450 3A4 and by human liver microsomes.
    Yamazaki H; Nakano M; Imai Y; Ueng YF; Guengerich FP; Shimada T
    Arch Biochem Biophys; 1996 Jan; 325(2):174-82. PubMed ID: 8561495
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Comparative study of monomeric reconstituted and membrane microsomal monooxygenase systems of the rabbit liver. II. Kinetic parameters of reductase and monooxygenase reactions.
    Kanaeva IP; Nikityuk OV; Davydov DR; Dedinskii IR; Koen YM; Kuznetsova GP; Skotselyas ED; Bachmanova GI; Archakov AI
    Arch Biochem Biophys; 1992 Nov; 298(2):403-12. PubMed ID: 1416971
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Optimization of yeast-expressed human liver cytochrome P450 3A4 catalytic activities by coexpressing NADPH-cytochrome P450 reductase and cytochrome b5.
    Peyronneau MA; Renaud JP; Truan G; Urban P; Pompon D; Mansuy D
    Eur J Biochem; 1992 Jul; 207(1):109-16. PubMed ID: 1628642
    [TBL] [Abstract][Full Text] [Related]  

  • 12. In vitro metabolism of terfenadine by a purified recombinant fusion protein containing cytochrome P4503A4 and NADPH-P450 reductase. Comparison to human liver microsomes and precision-cut liver tissue slices.
    Rodrigues AD; Mulford DJ; Lee RD; Surber BW; Kukulka MJ; Ferrero JL; Thomas SB; Shet MS; Estabrook RW
    Drug Metab Dispos; 1995 Jul; 23(7):765-75. PubMed ID: 7587966
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The effects of cytochrome b5, NADPH-P450 reductase, and lipid on the rate of 6 beta-hydroxylation of testosterone as catalyzed by a human P450 3A4 fusion protein.
    Shet MS; Faulkner KM; Holmans PL; Fisher CW; Estabrook RW
    Arch Biochem Biophys; 1995 Apr; 318(2):314-21. PubMed ID: 7733659
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Reconstitution of recombinant cytochrome P450 2C10(2C9) and comparison with cytochrome P450 3A4 and other forms: effects of cytochrome P450-P450 and cytochrome P450-b5 interactions.
    Yamazaki H; Gillam EM; Dong MS; Johnson WW; Guengerich FP; Shimada T
    Arch Biochem Biophys; 1997 Jun; 342(2):329-37. PubMed ID: 9186495
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Kinetics of ferric cytochrome P450 reduction by NADPH-cytochrome P450 reductase: rapid reduction in the absence of substrate and variations among cytochrome P450 systems.
    Guengerich FP; Johnson WW
    Biochemistry; 1997 Dec; 36(48):14741-50. PubMed ID: 9398194
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Regioselective biotransformation of midazolam by members of the human cytochrome P450 3A (CYP3A) subfamily.
    Gorski JC; Hall SD; Jones DR; VandenBranden M; Wrighton SA
    Biochem Pharmacol; 1994 Apr; 47(9):1643-53. PubMed ID: 8185679
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Mechanism-based inactivation of human liver cytochrome P450 2A6 by 8-methoxypsoralen.
    Koenigs LL; Peter RM; Thompson SJ; Rettie AE; Trager WF
    Drug Metab Dispos; 1997 Dec; 25(12):1407-15. PubMed ID: 9394031
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Roles of NADPH-P450 reductase and apo- and holo-cytochrome b5 on xenobiotic oxidations catalyzed by 12 recombinant human cytochrome P450s expressed in membranes of Escherichia coli.
    Yamazaki H; Nakamura M; Komatsu T; Ohyama K; Hatanaka N; Asahi S; Shimada N; Guengerich FP; Shimada T; Nakajima M; Yokoi T
    Protein Expr Purif; 2002 Apr; 24(3):329-37. PubMed ID: 11922748
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Requirements for cytochrome b5 in the oxidation of 7-ethoxycoumarin, chlorzoxazone, aniline, and N-nitrosodimethylamine by recombinant cytochrome P450 2E1 and by human liver microsomes.
    Yamazaki H; Nakano M; Gillam EM; Bell LC; Guengerich FP; Shimada T
    Biochem Pharmacol; 1996 Jul; 52(2):301-9. PubMed ID: 8694855
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Biochemical characterization of lauric acid omega-hydroxylation by a CYP4A1/NADPH-cytochrome P450 reductase fusion protein.
    Chaurasia CS; Alterman MA; Lu P; Hanzlik RP
    Arch Biochem Biophys; 1995 Feb; 317(1):161-9. PubMed ID: 7872779
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 34.