BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

264 related articles for article (PubMed ID: 11463831)

  • 1. Oncogenic Ras blocks anoikis by activation of a novel effector pathway independent of phosphatidylinositol 3-kinase.
    McFall A; Ulkü A; Lambert QT; Kusa A; Rogers-Graham K; Der CJ
    Mol Cell Biol; 2001 Aug; 21(16):5488-99. PubMed ID: 11463831
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Ras mediates radioresistance through both phosphatidylinositol 3-kinase-dependent and Raf-dependent but mitogen-activated protein kinase/extracellular signal-regulated kinase kinase-independent signaling pathways.
    Grana TM; Rusyn EV; Zhou H; Sartor CI; Cox AD
    Cancer Res; 2002 Jul; 62(14):4142-50. PubMed ID: 12124353
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Essential role of Raf in Ras transformation and deregulation of matrix metalloproteinase expression in ovarian epithelial cells.
    Ulkü AS; Schäfer R; Der CJ
    Mol Cancer Res; 2003 Dec; 1(14):1077-88. PubMed ID: 14707291
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Activation of the Raf-1/MAP kinase cascade is not sufficient for Ras transformation of RIE-1 epithelial cells.
    Oldham SM; Clark GJ; Gangarosa LM; Coffey RJ; Der CJ
    Proc Natl Acad Sci U S A; 1996 Jul; 93(14):6924-8. PubMed ID: 8692920
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ras-mediated loss of the pro-apoptotic response protein Par-4 is mediated by DNA hypermethylation through Raf-independent and Raf-dependent signaling cascades in epithelial cells.
    Pruitt K; Ulkü AS; Frantz K; Rojas RJ; Muniz-Medina VM; Rangnekar VM; Der CJ; Shields JM
    J Biol Chem; 2005 Jun; 280(24):23363-70. PubMed ID: 15831492
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Raf and RhoA cooperate to transform intestinal epithelial cells and induce growth resistance to transforming growth factor beta.
    Du J; Jiang B; Coffey RJ; Barnard J
    Mol Cancer Res; 2004 Apr; 2(4):233-41. PubMed ID: 15140945
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Rit, a non-lipid-modified Ras-related protein, transforms NIH3T3 cells without activating the ERK, JNK, p38 MAPK or PI3K/Akt pathways.
    Rusyn EV; Reynolds ER; Shao H; Grana TM; Chan TO; Andres DA; Cox AD
    Oncogene; 2000 Sep; 19(41):4685-94. PubMed ID: 11032018
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ras, but not Src, transformation of RIE-1 epithelial cells is dependent on activation of the mitogen-activated protein kinase cascade.
    Oldham SM; Cox AD; Reynolds ER; Sizemore NS; Coffey RJ; Der CJ
    Oncogene; 1998 May; 16(20):2565-73. PubMed ID: 9632133
    [TBL] [Abstract][Full Text] [Related]  

  • 9. A raf-independent epidermal growth factor receptor autocrine loop is necessary for Ras transformation of rat intestinal epithelial cells.
    Gangarosa LM; Sizemore N; Graves-Deal R; Oldham SM; Der CJ; Coffey RJ
    J Biol Chem; 1997 Jul; 272(30):18926-31. PubMed ID: 9228072
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Ras inactivation of the retinoblastoma pathway by distinct mechanisms in NIH 3T3 fibroblast and RIE-1 epithelial cells.
    Pruitt K; Pestell RG; Der CJ
    J Biol Chem; 2000 Dec; 275(52):40916-24. PubMed ID: 11007784
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Acquisition of anoikis resistance promotes alterations in the Ras/ERK and PI3K/Akt signaling pathways and matrix remodeling in endothelial cells.
    de Sousa Mesquita AP; de Araújo Lopes S; Pernambuco Filho PCA; Nader HB; Lopes CC
    Apoptosis; 2017 Sep; 22(9):1116-1137. PubMed ID: 28653224
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Opposing roles of the extracellular signal-regulated kinase and p38 mitogen-activated protein kinase cascades in Ras-mediated downregulation of tropomyosin.
    Shields JM; Mehta H; Pruitt K; Der CJ
    Mol Cell Biol; 2002 Apr; 22(7):2304-17. PubMed ID: 11884615
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Ras transformation of RIE-1 cells activates cap-independent translation of ornithine decarboxylase: regulation by the Raf/MEK/ERK and phosphatidylinositol 3-kinase pathways.
    Origanti S; Shantz LM
    Cancer Res; 2007 May; 67(10):4834-42. PubMed ID: 17510413
    [TBL] [Abstract][Full Text] [Related]  

  • 14. TC21 and Ras share indistinguishable transforming and differentiating activities.
    Graham SM; Oldham SM; Martin CB; Drugan JK; Zohn IE; Campbell S; Der CJ
    Oncogene; 1999 Mar; 18(12):2107-16. PubMed ID: 10321735
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Enhanced cathepsin L expression is mediated by different Ras effector pathways in fibroblasts and epithelial cells.
    Collette J; Ulku AS; Der CJ; Jones A; Erickson AH
    Int J Cancer; 2004 Nov; 112(2):190-9. PubMed ID: 15352030
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Akt/PKB activity is required for Ha-Ras-mediated transformation of intestinal epithelial cells.
    Sheng H; Shao J; DuBois RN
    J Biol Chem; 2001 Apr; 276(17):14498-504. PubMed ID: 11278613
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activated Ras prevents downregulation of Bcl-X(L) triggered by detachment from the extracellular matrix. A mechanism of Ras-induced resistance to anoikis in intestinal epithelial cells.
    Rosen K; Rak J; Leung T; Dean NM; Kerbel RS; Filmus J
    J Cell Biol; 2000 Apr; 149(2):447-56. PubMed ID: 10769035
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Raf-independent deregulation of p38 and JNK mitogen-activated protein kinases are critical for Ras transformation.
    Pruitt K; Pruitt WM; Bilter GK; Westwick JK; Der CJ
    J Biol Chem; 2002 Aug; 277(35):31808-17. PubMed ID: 12082106
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Involvement of Ras activation in human breast cancer cell signaling, invasion, and anoikis.
    Eckert LB; Repasky GA; Ulkü AS; McFall A; Zhou H; Sartor CI; Der CJ
    Cancer Res; 2004 Jul; 64(13):4585-92. PubMed ID: 15231670
    [TBL] [Abstract][Full Text] [Related]  

  • 20. The insulin-like growth factor I receptor is required for Akt activation and suppression of anoikis in cells transformed by the ETV6-NTRK3 chimeric tyrosine kinase.
    Martin MJ; Melnyk N; Pollard M; Bowden M; Leong H; Podor TJ; Gleave M; Sorensen PH
    Mol Cell Biol; 2006 Mar; 26(5):1754-69. PubMed ID: 16478996
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.