These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
144 related articles for article (PubMed ID: 11465948)
1. Antibody response to DT-GM, a novel fusion toxin consisting of a truncated diphtheria toxin (DT) linked to human granulocyte-macrophage colony stimulating factor (GM), during a phase I trial of patients with relapsed or refractory acute myeloid leukemia. Hall PD; Virella G; Willoughby T; Atchley DH; Kreitman RJ; Frankel AE Clin Immunol; 2001 Aug; 100(2):191-7. PubMed ID: 11465948 [TBL] [Abstract][Full Text] [Related]
2. Phase I trial of a novel diphtheria toxin/granulocyte macrophage colony-stimulating factor fusion protein (DT388GMCSF) for refractory or relapsed acute myeloid leukemia. Frankel AE; Powell BL; Hall PD; Case LD; Kreitman RJ Clin Cancer Res; 2002 May; 8(5):1004-13. PubMed ID: 12006512 [TBL] [Abstract][Full Text] [Related]
3. Reducing anti-DT IgG concentrations to improve the efficacy of a diphtheria fusion protein. Hall PD; Beagle KL; Garrett-Mayer E; Frankel AE Anticancer Drugs; 2008 Nov; 19(10):1007-11. PubMed ID: 18827566 [TBL] [Abstract][Full Text] [Related]
4. Diphtheria toxin fused to granulocyte-macrophage colony-stimulating factor eliminates acute myeloid leukemia cells with the potential to initiate leukemia in immunodeficient mice, but spares normal hemopoietic stem cells. Terpstra W; Rozemuller H; Breems DA; Rombouts EJ; Prins A; FitzGerald DJ; Kreitman RJ; Wielenga JJ; Ploemacher RE; Löwenberg B; Hagenbeek A; Martens AC Blood; 1997 Nov; 90(9):3735-42. PubMed ID: 9345060 [TBL] [Abstract][Full Text] [Related]
5. Toxicology and pharmacokinetics of DT388-GM-CSF, a fusion toxin consisting of a truncated diphtheria toxin (DT388) linked to human granulocyte-macrophage colony-stimulating factor (GM-CSF) in C57BL/6 mice. Hall PD; Kreitman RJ; Willingham MC; Frankel AE Toxicol Appl Pharmacol; 1998 May; 150(1):91-7. PubMed ID: 9630457 [TBL] [Abstract][Full Text] [Related]
6. The majority of children and adolescents with acute myeloid leukemia have detectable anti-DT388-GMCSF IgG concentrations, but at concentrations that should not preclude in vivo activity. Hall PD; Razzouk BI; Willoughby TE; McLean TW; Frankel AE J Pediatr Hematol Oncol; 2002 Oct; 24(7):521-6. PubMed ID: 12368687 [TBL] [Abstract][Full Text] [Related]
7. High-level expression and purification of the recombinant diphtheria fusion toxin DTGM for PHASE I clinical trials. Frankel AE; Ramage J; Latimer A; Feely T; Delatte S; Hall P; Tagge E; Kreitman R; Willingham M Protein Expr Purif; 1999 Jun; 16(1):190-201. PubMed ID: 10336877 [TBL] [Abstract][Full Text] [Related]
9. Production of recombinant DTctGMCSF fusion toxin in a baculovirus expression vector system for biotherapy of GMCSF-receptor positive hematologic malignancies. Williams MD; Rostovtsev A; Narla RK; Uckun FM Protein Expr Purif; 1998 Jul; 13(2):210-21. PubMed ID: 9675065 [TBL] [Abstract][Full Text] [Related]
10. Acute myeloid leukemia cells in G0 phase of the cell cycle that are unresponsive to conventional chemotherapy are sensitive to treatment with granulocyte-macrophage colony-stimulating factor/diphtheria toxin fusion proteins. Jedema I; Barge RM; Frankel AE; Willemze R; Falkenburg JH Exp Hematol; 2004 Feb; 32(2):188-94. PubMed ID: 15102480 [TBL] [Abstract][Full Text] [Related]
11. A diphtheria toxin-interleukin 3 fusion protein is cytotoxic to primitive acute myeloid leukemia progenitors but spares normal progenitors. Feuring-Buske M; Frankel AE; Alexander RL; Gerhard B; Hogge DE Cancer Res; 2002 Mar; 62(6):1730-6. PubMed ID: 11912147 [TBL] [Abstract][Full Text] [Related]
12. Toxicology and pharmacokinetics of DTGM, a fusion toxin consisting of a truncated diphtheria toxin (DT388) linked to human granulocyte-macrophage colony-stimulating factor, in cynomolgus monkeys. Hotchkiss CE; Hall PD; Cline JM; Willingham MC; Kreitman RJ; Gardin J; Latimer A; Ramage J; Feely T; DeLatte S; Tagge EP; Frankel AE Toxicol Appl Pharmacol; 1999 Jul; 158(2):152-60. PubMed ID: 10406930 [TBL] [Abstract][Full Text] [Related]
13. A recombinant fusion toxin targeted to the granulocyte-macrophage colony-stimulating factor receptor. Bendel AE; Shao Y; Davies SM; Warman B; Yang CH; Waddick KG; Uckun FM; Perentesis JP Leuk Lymphoma; 1997 Apr; 25(3-4):257-70. PubMed ID: 9168436 [TBL] [Abstract][Full Text] [Related]
14. Induction of apoptosis in multidrug-resistant and radiation-resistant acute myeloid leukemia cells by a recombinant fusion toxin directed against the human granulocyte macrophage colony-stimulating factor receptor. Perentesis JP; Waddick KG; Bendel AE; Shao Y; Warman BE; Chandan-Langlie M; Uckun FM Clin Cancer Res; 1997 Mar; 3(3):347-55. PubMed ID: 9815691 [TBL] [Abstract][Full Text] [Related]
15. Immunogenicity of granulocyte-macrophage colony-stimulating factor (GM-CSF) products in patients undergoing combination therapy with GM-CSF. Wadhwa M; Skog AL; Bird C; Ragnhammar P; Lilljefors M; Gaines-Das R; Mellstedt H; Thorpe R Clin Cancer Res; 1999 Jun; 5(6):1353-61. PubMed ID: 10389919 [TBL] [Abstract][Full Text] [Related]
16. Kinetics of development and characteristics of antibodies induced in cancer patients against yeast expressed rDNA derived granulocyte macrophage colony stimulating factor (GM-CSF). Rini B; Wadhwa M; Bird C; Small E; Gaines-Das R; Thorpe R Cytokine; 2005 Jan; 29(2):56-66. PubMed ID: 15598439 [TBL] [Abstract][Full Text] [Related]
17. DT388-GM-CSF, a novel fusion toxin consisting of a truncated diphtheria toxin fused to human granulocyte-macrophage colony-stimulating factor, prolongs host survival in a SCID mouse model of acute myeloid leukemia. Hall PD; Willingham MC; Kreitman RJ; Frankel AE Leukemia; 1999 Apr; 13(4):629-33. PubMed ID: 10214872 [TBL] [Abstract][Full Text] [Related]
18. Variable cytotoxicity of diphtheria toxin 388-granulocyte-macrophage colony-stimulating factor fusion protein for acute myelogenous leukemia stem cells. Feuring-Buske M; Frankel A; Gerhard B; Hogge D Exp Hematol; 2000 Dec; 28(12):1390-400. PubMed ID: 11146161 [TBL] [Abstract][Full Text] [Related]
19. Modulation of the apoptotic response of human myeloid leukemia cells to a diphtheria toxin granulocyte-macrophage colony-stimulating factor fusion protein. Frankel AE; Hall PD; Burbage C; Vesely J; Willingham M; Bhalla K; Kreitman RJ Blood; 1997 Nov; 90(9):3654-61. PubMed ID: 9345050 [TBL] [Abstract][Full Text] [Related]
20. In vivo biotherapy of HL-60 myeloid leukemia with a genetically engineered recombinant fusion toxin directed against the human granulocyte macrophage colony-stimulating factor receptor. Perentesis JP; Gunther R; Waurzyniak B; Yanishevski Y; Myers DE; Ek O; Messinger Y; Shao Y; Chelstrom LM; Schneider E; Evans WE; Uckun FM Clin Cancer Res; 1997 Dec; 3(12 Pt 1):2217-27. PubMed ID: 9815618 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]