334 related articles for article (PubMed ID: 11466313)
1. The transmembrane domain of the Alzheimer's beta-secretase (BACE1) determines its late Golgi localization and access to beta -amyloid precursor protein (APP) substrate.
Yan R; Han P; Miao H; Greengard P; Xu H
J Biol Chem; 2001 Sep; 276(39):36788-96. PubMed ID: 11466313
[TBL] [Abstract][Full Text] [Related]
2. BACE2 functions as an alternative alpha-secretase in cells.
Yan R; Munzner JB; Shuck ME; Bienkowski MJ
J Biol Chem; 2001 Sep; 276(36):34019-27. PubMed ID: 11423558
[TBL] [Abstract][Full Text] [Related]
3. Adaptor protein 2-mediated endocytosis of the β-secretase BACE1 is dispensable for amyloid precursor protein processing.
Prabhu Y; Burgos PV; Schindler C; Farías GG; Magadán JG; Bonifacino JS
Mol Biol Cell; 2012 Jun; 23(12):2339-51. PubMed ID: 22553349
[TBL] [Abstract][Full Text] [Related]
4. Processing amyloid precursor protein at the beta-site requires proper orientation to be accessed by BACE1.
Qahwash I; He W; Tomasselli A; Kletzien RF; Yan R
J Biol Chem; 2004 Sep; 279(37):39010-6. PubMed ID: 15234966
[TBL] [Abstract][Full Text] [Related]
5. PS1 Affects the Pathology of Alzheimer's Disease by Regulating BACE1 Distribution in the ER and BACE1 Maturation in the Golgi Apparatus.
Li N; Qiu Y; Wang H; Zhao J; Qing H
Int J Mol Sci; 2022 Dec; 23(24):. PubMed ID: 36555791
[TBL] [Abstract][Full Text] [Related]
6. Amyloid-β protein (Aβ) Glu11 is the major β-secretase site of β-site amyloid-β precursor protein-cleaving enzyme 1(BACE1), and shifting the cleavage site to Aβ Asp1 contributes to Alzheimer pathogenesis.
Deng Y; Wang Z; Wang R; Zhang X; Zhang S; Wu Y; Staufenbiel M; Cai F; Song W
Eur J Neurosci; 2013 Jun; 37(12):1962-9. PubMed ID: 23773065
[TBL] [Abstract][Full Text] [Related]
7. Beta-secretase cleavage at amino acid residue 34 in the amyloid beta peptide is dependent upon gamma-secretase activity.
Shi XP; Tugusheva K; Bruce JE; Lucka A; Wu GX; Chen-Dodson E; Price E; Li Y; Xu M; Huang Q; Sardana MK; Hazuda DJ
J Biol Chem; 2003 Jun; 278(23):21286-94. PubMed ID: 12665519
[TBL] [Abstract][Full Text] [Related]
8. Metabolism of the "Swedish" amyloid precursor protein variant in neuro2a (N2a) cells. Evidence that cleavage at the "beta-secretase" site occurs in the golgi apparatus.
Thinakaran G; Teplow DB; Siman R; Greenberg B; Sisodia SS
J Biol Chem; 1996 Apr; 271(16):9390-7. PubMed ID: 8621605
[TBL] [Abstract][Full Text] [Related]
9. Alzheimer's beta-secretase, beta-site amyloid precursor protein-cleaving enzyme, is responsible for cleavage secretion of a Golgi-resident sialyltransferase.
Kitazume S; Tachida Y; Oka R; Shirotani K; Saido TC; Hashimoto Y
Proc Natl Acad Sci U S A; 2001 Nov; 98(24):13554-9. PubMed ID: 11698669
[TBL] [Abstract][Full Text] [Related]
10. Alternative Selection of β-Site APP-Cleaving Enzyme 1 (BACE1) Cleavage Sites in Amyloid β-Protein Precursor (APP) Harboring Protective and Pathogenic Mutations within the Aβ Sequence.
Kimura A; Hata S; Suzuki T
J Biol Chem; 2016 Nov; 291(46):24041-24053. PubMed ID: 27687728
[TBL] [Abstract][Full Text] [Related]
11. Beta-secretase cleavage of Alzheimer's amyloid precursor protein by the transmembrane aspartic protease BACE.
Vassar R; Bennett BD; Babu-Khan S; Kahn S; Mendiaz EA; Denis P; Teplow DB; Ross S; Amarante P; Loeloff R; Luo Y; Fisher S; Fuller J; Edenson S; Lile J; Jarosinski MA; Biere AL; Curran E; Burgess T; Louis JC; Collins F; Treanor J; Rogers G; Citron M
Science; 1999 Oct; 286(5440):735-41. PubMed ID: 10531052
[TBL] [Abstract][Full Text] [Related]
12. BACE1: the beta-secretase enzyme in Alzheimer's disease.
Vassar R
J Mol Neurosci; 2004; 23(1-2):105-14. PubMed ID: 15126696
[TBL] [Abstract][Full Text] [Related]
13. Nicastrin, presenilin, APH-1, and PEN-2 form active gamma-secretase complexes in mitochondria.
Hansson CA; Frykman S; Farmery MR; Tjernberg LO; Nilsberth C; Pursglove SE; Ito A; Winblad B; Cowburn RF; Thyberg J; Ankarcrona M
J Biol Chem; 2004 Dec; 279(49):51654-60. PubMed ID: 15456764
[TBL] [Abstract][Full Text] [Related]
14. Structural features of human memapsin 2 (beta-secretase) and their biological and pathological implications.
Hong L; He X; Huang X; Chang W; Tang J
Acta Biochim Biophys Sin (Shanghai); 2004 Dec; 36(12):787-92. PubMed ID: 15592644
[TBL] [Abstract][Full Text] [Related]
15. PAR-4 is involved in regulation of beta-secretase cleavage of the Alzheimer amyloid precursor protein.
Xie J; Guo Q
J Biol Chem; 2005 Apr; 280(14):13824-32. PubMed ID: 15671026
[TBL] [Abstract][Full Text] [Related]
16. Beta-secretase/BACE1 promotes APP endocytosis and processing in the endosomes and on cell membrane.
Wang M; Jing T; Wang X; Yao D
Neurosci Lett; 2018 Oct; 685():63-67. PubMed ID: 30120949
[TBL] [Abstract][Full Text] [Related]
17. APP-BACE1 Interaction and Intracellular Localization Regulate Aβ Production in iPSC-Derived Cortical Neurons.
Roselli S; Satir TM; Camacho R; Fruhwürth S; Bergström P; Zetterberg H; Agholme L
Cell Mol Neurobiol; 2023 Oct; 43(7):3653-3668. PubMed ID: 37355492
[TBL] [Abstract][Full Text] [Related]
18. Distinct anterograde trafficking pathways of BACE1 and amyloid precursor protein from the TGN and the regulation of amyloid-β production.
Tan JZA; Fourriere L; Wang J; Perez F; Boncompain G; Gleeson PA
Mol Biol Cell; 2020 Jan; 31(1):27-44. PubMed ID: 31746668
[TBL] [Abstract][Full Text] [Related]
19. Association of gamma-secretase with lipid rafts in post-Golgi and endosome membranes.
Vetrivel KS; Cheng H; Lin W; Sakurai T; Li T; Nukina N; Wong PC; Xu H; Thinakaran G
J Biol Chem; 2004 Oct; 279(43):44945-54. PubMed ID: 15322084
[TBL] [Abstract][Full Text] [Related]
20. Employing a superior BACE1 cleavage sequence to probe cellular APP processing.
Tomasselli AG; Qahwash I; Emmons TL; Lu Y; Leone JW; Lull JM; Fok KF; Bannow CA; Smith CW; Bienkowski MJ; Heinrikson RL; Yan R
J Neurochem; 2003 Mar; 84(5):1006-17. PubMed ID: 12603825
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
