BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

187 related articles for article (PubMed ID: 11470754)

  • 1. Presence of benzo[a]pyrene diol epoxide adducts in target DNA leads to an increase in UV-induced DNA single strand breaks and supF gene mutations.
    Routledge MN; McLuckie KI; Jones GD; Farmer PB; Martin EA
    Carcinogenesis; 2001 Aug; 22(8):1231-8. PubMed ID: 11470754
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Effects of the order of exposure to a binary mixture of mutagens on the induced mutation spectra in the supF gene.
    McLuckie KI; Gaskell M; Farmer PB; Martin EA; Jones GD; Routledge MN
    Mutagenesis; 2004 Mar; 19(2):137-41. PubMed ID: 14981160
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutagenic potential of benzo[a]pyrene-derived DNA adducts positioned in codon 273 of the human P53 gene.
    Dong H; Bonala RR; Suzuki N; Johnson F; Grollman AP; Shibutani S
    Biochemistry; 2004 Dec; 43(50):15922-8. PubMed ID: 15595848
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Arsenite enhances the benzo[a]pyrene diol epoxide (BPDE)-induced mutagenesis with no marked effect on repair of BPDE-DNA adducts in human lung cells.
    Chiang HC; Tsou TC
    Toxicol In Vitro; 2009 Aug; 23(5):897-905. PubMed ID: 19470404
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ability of adducts formed in a shuttle vector by reactive metabolites of 1-nitropyrene and benzo(a)pyrene to induce mutations when the plasmid replicates in human cells.
    Maher VM; Yang JL; McCormick JJ
    Acta Biol Hung; 1990; 41(1-3):173-86. PubMed ID: 2128787
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Methylated CpG dinucleotides are the preferential targets for G-to-T transversion mutations induced by benzo[a]pyrene diol epoxide in mammalian cells: similarities with the p53 mutation spectrum in smoking-associated lung cancers.
    Yoon JH; Smith LE; Feng Z; Tang M; Lee CS; Pfeifer GP
    Cancer Res; 2001 Oct; 61(19):7110-7. PubMed ID: 11585742
    [TBL] [Abstract][Full Text] [Related]  

  • 7. In vivo and in vitro replication consequences of stereoisomeric benzo[a]pyrene-7,8-dihydrodiol 9,10-epoxide adducts on adenine N6 at the second position of N-ras codon 61.
    Chary P; Latham GJ; Robberson DL; Kim SJ; Han S; Harris CM; Harris TM; Lloyd RS
    J Biol Chem; 1995 Mar; 270(10):4990-5000. PubMed ID: 7890605
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Mutational specificity of the (+)-anti-diol epoxide of benzo[a]pyrene in a supF gene of an Escherichia coli plasmid: DNA sequence context influences hotspots, mutagenic specificity and the extent of SOS enhancement of mutagenesis.
    Rodriguez H; Loechler EL
    Carcinogenesis; 1993 Mar; 14(3):373-83. PubMed ID: 8453713
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Enhanced sensitivity to anti-benzo(a)pyrene-diol-epoxide DNA damage correlates with decreased global genomic repair attributable to abrogated p53 function in human cells.
    Wani MA; Zhu Q; El-Mahdy M; Venkatachalam S; Wani AA
    Cancer Res; 2000 Apr; 60(8):2273-80. PubMed ID: 10786695
    [TBL] [Abstract][Full Text] [Related]  

  • 10. A comparative investigation of DNA adducts, DNA strand breaks and gene mutations induced by benzo[a]pyrene and (+/-)-anti-benzo[a]pyrene-7,8-diol 9,10-oxide in cultured human cells.
    Hanelt S; Helbig R; Hartmann A; Lang M; Seidel A; Speit G
    Mutat Res; 1997 Apr; 390(1-2):179-88. PubMed ID: 9150767
    [TBL] [Abstract][Full Text] [Related]  

  • 11. TP53 mutations induced by BPDE in Xpa-WT and Xpa-Null human TP53 knock-in (Hupki) mouse embryo fibroblasts.
    Kucab JE; van Steeg H; Luijten M; Schmeiser HH; White PA; Phillips DH; Arlt VM
    Mutat Res; 2015 Mar; 773():48-62. PubMed ID: 25847421
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Kinds of mutations formed when a shuttle vector containing adducts of (+/-)-7 beta, 8 alpha-dihydroxy-9 alpha, 10 alpha-epoxy-7,8,9, 10-tetrahydrobenzo[a]pyrene replicates in human cells.
    Yang JL; Maher VM; McCormick JJ
    Proc Natl Acad Sci U S A; 1987 Jun; 84(11):3787-91. PubMed ID: 3108878
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Kinds and spectrum of mutations induced by 1-nitrosopyrene adducts during plasmid replication in human cells.
    Yang JL; Maher VM; McCormick JJ
    Mol Cell Biol; 1988 Aug; 8(8):3364-72. PubMed ID: 3062380
    [TBL] [Abstract][Full Text] [Related]  

  • 14. NAD(P)H:quinone oxidoreductase 1 reduces the mutagenicity of DNA caused by NADPH:P450 reductase-activated metabolites of benzo(a)pyrene quinones.
    Joseph P; Jaiswal AK
    Br J Cancer; 1998 Mar; 77(5):709-19. PubMed ID: 9514048
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Fidelity of translesional synthesis past benzo[a]pyrene diol epoxide-2'-deoxyguanosine DNA adducts: marked effects of host cell, sequence context, and chirality.
    Moriya M; Spiegel S; Fernandes A; Amin S; Liu T; Geacintov N; Grollman AP
    Biochemistry; 1996 Dec; 35(51):16646-51. PubMed ID: 8988000
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Comparing the frequency and spectra of mutations induced when an SV-40 based shuttle vector containing covalently bound residues of structurally-related carcinogens replicates in human cells.
    Maher VM; Yang JL; Mah MC; McCormick JJ
    Mutat Res; 1989; 220(2-3):83-92. PubMed ID: 2538743
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Preferential repair and strand-specific repair of benzo[a]pyrene diol epoxide adducts in the HPRT gene of diploid human fibroblasts.
    Chen RH; Maher VM; Brouwer J; van de Putte P; McCormick JJ
    Proc Natl Acad Sci U S A; 1992 Jun; 89(12):5413-7. PubMed ID: 1608950
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Genetic polymorphisms in biotransformation enzymes for benzo[a]pyrene and related levels of benzo[a]pyrene-7,8-diol-9,10-epoxide-DNA adducts in Goeckerman therapy.
    Beranek M; Fiala Z; Kremlacek J; Andrys C; Hamakova K; Chmelarova M; Palicka V; Borska L
    Toxicol Lett; 2016 Jul; 255():47-51. PubMed ID: 27188524
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Mutagenic selectivity at the HPRT locus in V-79 cells: comparison of mutations caused by bay-region benzo[a]pyrene 7,8-diol-9,-10-epoxide enantiomers with high and low carcinogenic activity.
    Wei SJ; Chang RL; Hennig E; Cui XX; Merkler KA; Wong CQ; Yagi H; Jerina DM; Conney AH
    Carcinogenesis; 1994 Aug; 15(8):1729-35. PubMed ID: 8055656
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Removal of benzo(a)pyrene diol epoxide (BPDE)-DNA adducts as a measure of DNA repair capacity in lymphoblastoid cell lines from sisters discordant for breast cancer.
    Motykiewicz G; Faraglia B; Wang LW; Terry MB; Senie RT; Santella RM
    Environ Mol Mutagen; 2002; 40(2):93-100. PubMed ID: 12203401
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.