BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

735 related articles for article (PubMed ID: 11471548)

  • 1. Role of transcription factor Nrf2 in the induction of hepatic phase 2 and antioxidative enzymes in vivo by the cancer chemoprotective agent, 3H-1, 2-dimethiole-3-thione.
    Kwak MK; Itoh K; Yamamoto M; Sutter TR; Kensler TW
    Mol Med; 2001 Feb; 7(2):135-45. PubMed ID: 11471548
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Sensitivity to carcinogenesis is increased and chemoprotective efficacy of enzyme inducers is lost in nrf2 transcription factor-deficient mice.
    Ramos-Gomez M; Kwak MK; Dolan PM; Itoh K; Yamamoto M; Talalay P; Kensler TW
    Proc Natl Acad Sci U S A; 2001 Mar; 98(6):3410-5. PubMed ID: 11248092
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role of Nrf2 signaling in regulation of antioxidants and phase 2 enzymes in cardiac fibroblasts: protection against reactive oxygen and nitrogen species-induced cell injury.
    Zhu H; Itoh K; Yamamoto M; Zweier JL; Li Y
    FEBS Lett; 2005 Jun; 579(14):3029-36. PubMed ID: 15896789
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Enhanced expression of the transcription factor Nrf2 by cancer chemopreventive agents: role of antioxidant response element-like sequences in the nrf2 promoter.
    Kwak MK; Itoh K; Yamamoto M; Kensler TW
    Mol Cell Biol; 2002 May; 22(9):2883-92. PubMed ID: 11940647
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The Cap'n'Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and glutathione biosynthetic enzymes.
    McMahon M; Itoh K; Yamamoto M; Chanas SA; Henderson CJ; McLellan LI; Wolf CR; Cavin C; Hayes JD
    Cancer Res; 2001 Apr; 61(8):3299-307. PubMed ID: 11309284
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Evaluation of the cancer chemopreventive potency of dithiolethione analogs of oltipraz.
    Roebuck BD; Curphey TJ; Li Y; Baumgartner KJ; Bodreddigari S; Yan J; Gange SJ; Kensler TW; Sutter TR
    Carcinogenesis; 2003 Dec; 24(12):1919-28. PubMed ID: 14555609
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The chemical inducibility of mouse cardiac antioxidants and phase 2 enzymes in vivo.
    Cao Z; Li Y
    Biochem Biophys Res Commun; 2004 May; 317(4):1080-8. PubMed ID: 15094379
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Induction of Nrf2-regulated genes by 3H-1, 2-dithiole-3-thione through the ERK signaling pathway in murine keratinocytes.
    Manandhar S; Cho JM; Kim JA; Kensler TW; Kwak MK
    Eur J Pharmacol; 2007 Dec; 577(1-3):17-27. PubMed ID: 17854798
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Nuclear factor E2-related factor 2-dependent myocardiac cytoprotection against oxidative and electrophilic stress.
    Zhu H; Jia Z; Misra BR; Zhang L; Cao Z; Yamamoto M; Trush MA; Misra HP; Li Y
    Cardiovasc Toxicol; 2008; 8(2):71-85. PubMed ID: 18463988
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Isolation of cDNAs representing dithiolethione-responsive genes.
    Primiano T; Gastel JA; Kensler TW; Sutter TR
    Carcinogenesis; 1996 Nov; 17(11):2297-303. PubMed ID: 8968041
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Modulation of gene expression by cancer chemopreventive dithiolethiones through the Keap1-Nrf2 pathway. Identification of novel gene clusters for cell survival.
    Kwak MK; Wakabayashi N; Itoh K; Motohashi H; Yamamoto M; Kensler TW
    J Biol Chem; 2003 Mar; 278(10):8135-45. PubMed ID: 12506115
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray.
    Thimmulappa RK; Mai KH; Srisuma S; Kensler TW; Yamamoto M; Biswal S
    Cancer Res; 2002 Sep; 62(18):5196-203. PubMed ID: 12234984
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Chemoprotective 3H-1,2-dithiole-3-thione induces antioxidant genes in vivo.
    Otieno MA; Kensler TW; Guyton KZ
    Free Radic Biol Med; 2000 Mar; 28(6):944-52. PubMed ID: 10802226
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Nrf2 mediates the induction of ferritin H in response to xenobiotics and cancer chemopreventive dithiolethiones.
    Pietsch EC; Chan JY; Torti FM; Torti SV
    J Biol Chem; 2003 Jan; 278(4):2361-9. PubMed ID: 12435735
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Antioxidants and phase 2 enzymes in cardiomyocytes: Chemical inducibility and chemoprotection against oxidant and simulated ischemia-reperfusion injury.
    Cao Z; Zhu H; Zhang L; Zhao X; Zweier JL; Li Y
    Exp Biol Med (Maywood); 2006 Sep; 231(8):1353-64. PubMed ID: 16946404
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Protective effect of 3H-1, 2-dithiole-3-thione on cellular model of Alzheimer's disease involves Nrf2/ARE signaling pathway.
    Wang L; Wang M; Hu J; Shen W; Hu J; Yao Y; Wang X; Afzal CM; Ma R; Li G
    Eur J Pharmacol; 2017 Jan; 795():115-123. PubMed ID: 27939991
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Structure-activity relationships in the induction of Phase II enzymes by derivatives of 3H-1,2-dithiole-3-thione in rats.
    Munday R; Zhang Y; Munday CM; Li J
    Chem Biol Interact; 2006 Mar; 160(2):115-22. PubMed ID: 16458871
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Potent inhibition of aflatoxin-induced hepatic tumorigenesis by the monofunctional enzyme inducer 1,2-dithiole-3-thione.
    Kensler TW; Groopman JD; Eaton DL; Curphey TJ; Roebuck BD
    Carcinogenesis; 1992 Jan; 13(1):95-100. PubMed ID: 1346373
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Cruciferous dithiolethione-mediated coordinated induction of total cellular and mitochondrial antioxidants and phase 2 enzymes in human primary cardiomyocytes: cytoprotection against oxidative/electrophilic stress and doxorubicin toxicity.
    Zhu H; Jia Z; Zhou K; Misra HP; Santo A; Gabrielson KL; Li Y
    Exp Biol Med (Maywood); 2009 Apr; 234(4):418-29. PubMed ID: 19176875
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Antioxidants and phase 2 enzymes in macrophages: regulation by Nrf2 signaling and protection against oxidative and electrophilic stress.
    Zhu H; Jia Z; Zhang L; Yamamoto M; Misra HP; Trush MA; Li Y
    Exp Biol Med (Maywood); 2008 Apr; 233(4):463-74. PubMed ID: 18367636
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 37.