These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

127 related articles for article (PubMed ID: 11474885)

  • 1. [Cytotoxicity of beta-lapachone, an naphthoquinone with possible therapeutic use].
    Dubin M; Fernandez Villamil SH; Stoppani AO
    Medicina (B Aires); 2001; 61(3):343-50. PubMed ID: 11474885
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Activation of c-Jun NH2-terminal kinase and subsequent CPP32/Yama during topoisomerase inhibitor beta-lapachone-induced apoptosis through an oxidation-dependent pathway.
    Shiah SG; Chuang SE; Chau YP; Shen SC; Kuo ML
    Cancer Res; 1999 Jan; 59(2):391-8. PubMed ID: 9927052
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Peroxiredoxin 1 knockdown potentiates β-lapachone cytotoxicity through modulation of reactive oxygen species and mitogen-activated protein kinase signals.
    He T; Banach-Latapy A; Vernis L; Dardalhon M; Chanet R; Huang ME
    Carcinogenesis; 2013 Apr; 34(4):760-9. PubMed ID: 23239746
    [TBL] [Abstract][Full Text] [Related]  

  • 4. beta-Lapachone-induced apoptosis in human prostate cancer cells: involvement of NQO1/xip3.
    Planchon SM; Pink JJ; Tagliarino C; Bornmann WG; Varnes ME; Boothman DA
    Exp Cell Res; 2001 Jul; 267(1):95-106. PubMed ID: 11412042
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mu-calpain activation in beta-lapachone-mediated apoptosis.
    Tagliarino C; Pink JJ; Reinicke KE; Simmers SM; Wuerzberger-Davis SM; Boothman DA
    Cancer Biol Ther; 2003; 2(2):141-52. PubMed ID: 12750552
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Prostate cancer radiosensitization through poly(ADP-Ribose) polymerase-1 hyperactivation.
    Dong Y; Bey EA; Li LS; Kabbani W; Yan J; Xie XJ; Hsieh JT; Gao J; Boothman DA
    Cancer Res; 2010 Oct; 70(20):8088-96. PubMed ID: 20940411
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Induction of CDK inhibitors (p21(WAF1) and p27(Kip1)) and Bak in the beta-lapachone-induced apoptosis of human prostate cancer cells.
    Don MJ; Chang YH; Chen KK; Ho LK; Chau YP
    Mol Pharmacol; 2001 Apr; 59(4):784-94. PubMed ID: 11259623
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Phosphorylation of p53, induction of Bax and activation of caspases during beta-lapachone-mediated apoptosis in human prostate epithelial cells.
    Choi YH; Kim MJ; Lee SY; Lee YN; Chi GY; Eom HS; Kim ND; Choi BT
    Int J Oncol; 2002 Dec; 21(6):1293-9. PubMed ID: 12429980
    [TBL] [Abstract][Full Text] [Related]  

  • 9. beta-lapachone, a novel plant product, overcomes drug resistance in human multiple myeloma cells.
    Gupta D; Podar K; Tai YT; Lin B; Hideshima T; Akiyama M; LeBlanc R; Catley L; Mitsiades N; Mitsiades C; Chauhan D; Munshi NC; Anderson KC
    Exp Hematol; 2002 Jul; 30(7):711-20. PubMed ID: 12135668
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Nonhomologous end joining is essential for cellular resistance to the novel antitumor agent, beta-lapachone.
    Bentle MS; Reinicke KE; Dong Y; Bey EA; Boothman DA
    Cancer Res; 2007 Jul; 67(14):6936-45. PubMed ID: 17638905
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An NQO1- and PARP-1-mediated cell death pathway induced in non-small-cell lung cancer cells by beta-lapachone.
    Bey EA; Bentle MS; Reinicke KE; Dong Y; Yang CR; Girard L; Minna JD; Bornmann WG; Gao J; Boothman DA
    Proc Natl Acad Sci U S A; 2007 Jul; 104(28):11832-7. PubMed ID: 17609380
    [TBL] [Abstract][Full Text] [Related]  

  • 12. X-ray repair cross-complementing protein 1 (XRCC1) loss promotes β-lapachone -induced apoptosis in pancreatic cancer cells.
    Zheng Y; Zhang H; Guo Y; Chen Y; Chen H; Liu Y
    BMC Cancer; 2021 Nov; 21(1):1234. PubMed ID: 34789190
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Cancer therapy with beta-lapachone.
    Pardee AB; Li YZ; Li CJ
    Curr Cancer Drug Targets; 2002 Sep; 2(3):227-42. PubMed ID: 12188909
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Modulating endogenous NQO1 levels identifies key regulatory mechanisms of action of β-lapachone for pancreatic cancer therapy.
    Li LS; Bey EA; Dong Y; Meng J; Patra B; Yan J; Xie XJ; Brekken RA; Barnett CC; Bornmann WG; Gao J; Boothman DA
    Clin Cancer Res; 2011 Jan; 17(2):275-85. PubMed ID: 21224367
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Catalase abrogates β-lapachone-induced PARP1 hyperactivation-directed programmed necrosis in NQO1-positive breast cancers.
    Bey EA; Reinicke KE; Srougi MC; Varnes M; Anderson VE; Pink JJ; Li LS; Patel M; Cao L; Moore Z; Rommel A; Boatman M; Lewis C; Euhus DM; Bornmann WG; Buchsbaum DJ; Spitz DR; Gao J; Boothman DA
    Mol Cancer Ther; 2013 Oct; 12(10):2110-20. PubMed ID: 23883585
    [TBL] [Abstract][Full Text] [Related]  

  • 16. An NQO1 substrate with potent antitumor activity that selectively kills by PARP1-induced programmed necrosis.
    Huang X; Dong Y; Bey EA; Kilgore JA; Bair JS; Li LS; Patel M; Parkinson EI; Wang Y; Williams NS; Gao J; Hergenrother PJ; Boothman DA
    Cancer Res; 2012 Jun; 72(12):3038-47. PubMed ID: 22532167
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Bcl-2 protects against beta-lapachone-mediated caspase 3 activation and apoptosis in human myeloid leukemia (HL-60) cells.
    Planchon SM; Wuerzberger-Davis SM; Pink JJ; Robertson KA; Bornmann WG; Boothman DA
    Oncol Rep; 1999; 6(3):485-92. PubMed ID: 10203579
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Yeast cytotoxic sensitivity to the antitumour agent β-lapachone depends mainly on oxidative stress and is largely independent of microtubule- or topoisomerase-mediated DNA damage.
    Ramos-Pérez C; Lorenzo-Castrillejo I; Quevedo O; García-Luis J; Matos-Perdomo E; Medina-Coello C; Estévez-Braun A; Machín F
    Biochem Pharmacol; 2014 Nov; 92(2):206-19. PubMed ID: 25241291
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of poly(ADP-ribose) polymerase activation attenuates beta-lapachone-induced necrotic cell death in human osteosarcoma cells.
    Liu TJ; Lin SY; Chau YP
    Toxicol Appl Pharmacol; 2002 Jul; 182(2):116-25. PubMed ID: 12140175
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Trypanosoma cruzi: death phenotypes induced by ortho-naphthoquinone substrates of the aldo-keto reductase (TcAKR). Role of this enzyme in the mechanism of action of β-lapachone.
    Garavaglia PA; Rubio MF; Laverrière M; Tasso LM; Fichera LE; Cannata JJB; García GA
    Parasitology; 2018 Aug; 145(9):1251-1259. PubMed ID: 29400267
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.