BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

346 related articles for article (PubMed ID: 11485027)

  • 1. The Tet-On system in transgenic mice: inhibition of the mouse pdx-1 gene activity by antisense RNA expression in pancreatic beta-cells.
    Lottmann H; Vanselow J; Hessabi B; Walther R
    J Mol Med (Berl); 2001 Jun; 79(5-6):321-8. PubMed ID: 11485027
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Overexpression of c-Myc in beta-cells of transgenic mice causes proliferation and apoptosis, downregulation of insulin gene expression, and diabetes.
    Laybutt DR; Weir GC; Kaneto H; Lebet J; Palmiter RD; Sharma A; Bonner-Weir S
    Diabetes; 2002 Jun; 51(6):1793-804. PubMed ID: 12031967
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Profound defects in pancreatic beta-cell function in mice with combined heterozygous mutations in Pdx-1, Hnf-1alpha, and Hnf-3beta.
    Shih DQ; Heimesaat M; Kuwajima S; Stein R; Wright CV; Stoffel M
    Proc Natl Acad Sci U S A; 2002 Mar; 99(6):3818-23. PubMed ID: 11904435
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of pancreatic beta-cell glucokinase by antisense RNA expression in transgenic mice: mouse strain-dependent alteration of glucose tolerance.
    Ishihara H; Tashiro F; Ikuta K; Asano T; Katagiri H; Inukai K; Kikuchi M; Yazaki Y; Oka Y; Miyazaki J
    FEBS Lett; 1995 Sep; 371(3):329-32. PubMed ID: 7556622
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hepatocyte nuclear factor 3beta is involved in pancreatic beta-cell-specific transcription of the pdx-1 gene.
    Wu KL; Gannon M; Peshavaria M; Offield MF; Henderson E; Ray M; Marks A; Gamer LW; Wright CV; Stein R
    Mol Cell Biol; 1997 Oct; 17(10):6002-13. PubMed ID: 9315659
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Fatty acids decrease IDX-1 expression in rat pancreatic islets and reduce GLUT2, glucokinase, insulin, and somatostatin levels.
    Gremlich S; Bonny C; Waeber G; Thorens B
    J Biol Chem; 1997 Nov; 272(48):30261-9. PubMed ID: 9374511
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Endocrine pancreas in insulin receptor-deficient mouse pups.
    Jackerott M; Baudry A; Lamothe B; Bucchini D; Jami J; Joshi RL
    Diabetes; 2001 Feb; 50 Suppl 1():S146-9. PubMed ID: 11272177
    [TBL] [Abstract][Full Text] [Related]  

  • 8. The PDX-1 activation domain provides specific functions necessary for transcriptional stimulation in pancreatic beta-cells.
    Peshavaria M; Cissell MA; Henderson E; Petersen HV; Stein R
    Mol Endocrinol; 2000 Dec; 14(12):1907-17. PubMed ID: 11117522
    [TBL] [Abstract][Full Text] [Related]  

  • 9. The loss of GLUT2 expression in the pancreatic beta-cells of diabetic db/db mice is associated with an impaired DNA-binding activity of islet-specific trans-acting factors.
    Bonny C; Roduit R; Gremlich S; Nicod P; Thorens B; Waeber G
    Mol Cell Endocrinol; 1997 Nov; 135(1):59-65. PubMed ID: 9453241
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Altered beta-cell distribution of pdx-1 and GLUT-2 after a short-term challenge with a high-fat diet in C57BL/6J mice.
    Reimer MK; Ahrén B
    Diabetes; 2002 Feb; 51 Suppl 1():S138-43. PubMed ID: 11815473
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Suppression of Pdx-1 perturbs proinsulin processing, insulin secretion and GLP-1 signalling in INS-1 cells.
    Wang H; Iezzi M; Theander S; Antinozzi PA; Gauthier BR; Halban PA; Wollheim CB
    Diabetologia; 2005 Apr; 48(4):720-31. PubMed ID: 15756539
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Transcriptional activation of the GLUT2 gene by the IPF-1/STF-1/IDX-1 homeobox factor.
    Waeber G; Thompson N; Nicod P; Bonny C
    Mol Endocrinol; 1996 Nov; 10(11):1327-34. PubMed ID: 8923459
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Transforming growth factor beta induction of insulin gene expression is mediated by pancreatic and duodenal homeobox gene-1 in rat insulinoma cells.
    Sayo Y; Hosokawa H; Imachi H; Murao K; Sato M; Wong NC; Ishida T; Takahara J
    Eur J Biochem; 2000 Feb; 267(4):971-8. PubMed ID: 10672004
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Reduced PDX-1 expression impairs islet response to insulin resistance and worsens glucose homeostasis.
    Brissova M; Blaha M; Spear C; Nicholson W; Radhika A; Shiota M; Charron MJ; Wright CV; Powers AC
    Am J Physiol Endocrinol Metab; 2005 Apr; 288(4):E707-14. PubMed ID: 15562255
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Persistent expression of HNF6 in islet endocrine cells causes disrupted islet architecture and loss of beta cell function.
    Gannon M; Ray MK; Van Zee K; Rausa F; Costa RH; Wright CV
    Development; 2000 Jul; 127(13):2883-95. PubMed ID: 10851133
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Suppression of transcription factor PDX-1/IPF1/STF-1/IDX-1 causes no decrease in insulin mRNA in MIN6 cells.
    Kajimoto Y; Watada H; Matsuoka Ta; Kaneto H; Fujitani Y; Miyazaki J; Yamasaki Y
    J Clin Invest; 1997 Oct; 100(7):1840-6. PubMed ID: 9312185
    [TBL] [Abstract][Full Text] [Related]  

  • 17. beta-cell-specific inactivation of the mouse Ipf1/Pdx1 gene results in loss of the beta-cell phenotype and maturity onset diabetes.
    Ahlgren U; Jonsson J; Jonsson L; Simu K; Edlund H
    Genes Dev; 1998 Jun; 12(12):1763-8. PubMed ID: 9637677
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ca2+/calmodulin-dependent protein kinase II delta2 regulates gene expression of insulin in INS-1 rat insulinoma cells.
    Osterhoff M; Möhlig M; Schwanstecher M; Seufert J; Ortmann J; Schatz H; Pfeiffer AF
    Cell Calcium; 2003 Mar; 33(3):175-84. PubMed ID: 12600804
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Negative regulation of pancreatic and duodenal homeobox-1 by somatostatin receptor subtype 5.
    Zhou G; Liu SH; Shahi KM; Wang H; Duan X; Lin X; Feng XH; Li M; Fisher WE; Demayo FJ; Dawson D; Brunicardi FC
    Mol Endocrinol; 2012 Jul; 26(7):1225-34. PubMed ID: 22669743
    [TBL] [Abstract][Full Text] [Related]  

  • 20. High glucose-induced impairment in insulin secretion is associated with reduction in islet glucokinase in a mouse model of susceptibility to islet dysfunction.
    Kooptiwut S; Kebede M; Zraika S; Visinoni S; Aston-Mourney K; Favaloro J; Tikellis C; Thomas MC; Forbes JM; Cooper ME; Dunlop M; Proietto J; Andrikopoulos S
    J Mol Endocrinol; 2005 Aug; 35(1):39-48. PubMed ID: 16087720
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 18.