BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

329 related articles for article (PubMed ID: 11485999)

  • 1. alpha-Lactalbumin (LA) stimulates milk beta-1,4-galactosyltransferase I (beta 4Gal-T1) to transfer glucose from UDP-glucose to N-acetylglucosamine. Crystal structure of beta 4Gal-T1 x LA complex with UDP-Glc.
    Ramakrishnan B; Shah PS; Qasba PK
    J Biol Chem; 2001 Oct; 276(40):37665-71. PubMed ID: 11485999
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Comparison of the closed conformation of the beta 1,4-galactosyltransferase-1 (beta 4Gal-T1) in the presence and absence of alpha-lactalbumin (LA).
    Ramakrishnan B; Qasba PK
    J Biomol Struct Dyn; 2003 Aug; 21(1):1-8. PubMed ID: 12854954
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Mutation of arginine 228 to lysine enhances the glucosyltransferase activity of bovine beta-1,4-galactosyltransferase I.
    Ramakrishnan B; Boeggeman E; Qasba PK
    Biochemistry; 2005 Mar; 44(9):3202-10. PubMed ID: 15736931
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structure-based design of beta 1,4-galactosyltransferase I (beta 4Gal-T1) with equally efficient N-acetylgalactosaminyltransferase activity: point mutation broadens beta 4Gal-T1 donor specificity.
    Ramakrishnan B; Qasba PK
    J Biol Chem; 2002 Jun; 277(23):20833-9. PubMed ID: 11916963
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The kinetic mechansim of bovine milk galactosyltransferase. The role of alpha-lactalbumin.
    Bell JE; Beyer TA; Hill RL
    J Biol Chem; 1976 May; 251(10):3003-13. PubMed ID: 818085
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Crystal structure of lactose synthase reveals a large conformational change in its catalytic component, the beta1,4-galactosyltransferase-I.
    Ramakrishnan B; Qasba PK
    J Mol Biol; 2001 Jun; 310(1):205-18. PubMed ID: 11419947
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Alpha-lactalbumin induces bovine milk beta 1,4-galactosyltransferase to utilize UDP-GalNAc.
    Do KY; Do SI; Cummings RD
    J Biol Chem; 1995 Aug; 270(31):18447-51. PubMed ID: 7629170
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Structural snapshots of beta-1,4-galactosyltransferase-I along the kinetic pathway.
    Ramakrishnan B; Ramasamy V; Qasba PK
    J Mol Biol; 2006 Apr; 357(5):1619-33. PubMed ID: 16497331
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Ehrlich ascites tumor cell UDP-Gal:N-acetyl-D-glucosamine beta(1,4)-galactosyltransferase. Purification, characterization, and topography of the acceptor-binding site.
    Elices MJ; Goldstein IJ
    J Biol Chem; 1988 Mar; 263(7):3354-62. PubMed ID: 3125179
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Crystal structure of beta1,4-galactosyltransferase complex with UDP-Gal reveals an oligosaccharide acceptor binding site.
    Ramakrishnan B; Balaji PV; Qasba PK
    J Mol Biol; 2002 Apr; 318(2):491-502. PubMed ID: 12051854
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Effect of the Met344His mutation on the conformational dynamics of bovine beta-1,4-galactosyltransferase: crystal structure of the Met344His mutant in complex with chitobiose.
    Ramakrishnan B; Boeggeman E; Qasba PK
    Biochemistry; 2004 Oct; 43(39):12513-22. PubMed ID: 15449940
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Roles of individual enzyme-substrate interactions by alpha-1,3-galactosyltransferase in catalysis and specificity.
    Zhang Y; Swaminathan GJ; Deshpande A; Boix E; Natesh R; Xie Z; Acharya KR; Brew K
    Biochemistry; 2003 Nov; 42(46):13512-21. PubMed ID: 14621997
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Fragment-based screening of the donor substrate specificity of human blood group B galactosyltransferase using saturation transfer difference NMR.
    Blume A; Angulo J; Biet T; Peters H; Benie AJ; Palcic M; Peters T
    J Biol Chem; 2006 Oct; 281(43):32728-40. PubMed ID: 16923820
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Human ovarian cancer, lymphoma spleen, and bovine milk GlcNAc:beta1,4Gal/GalNAc transferases: two molecular species in ovarian tumor and induction of GalNAcbeta1,4Glc synthesis by alpha-lactalbumin.
    Chandrasekaran EV; Chawda R; Piskorz C; Locke RD; Ta A; Sharad G; Odunsi K; Lele S; Matta KL
    Carbohydr Res; 2001 Aug; 334(2):105-18. PubMed ID: 11502266
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Changing the donor cofactor of bovine alpha 1, 3-galactosyltransferase by fusion with UDP-galactose 4-epimerase. More efficient biocatalysis for synthesis of alpha-Gal epitopes.
    Chen X; Liu Z; Wang J; Fang J; Fan H; Wang PG
    J Biol Chem; 2000 Oct; 275(41):31594-600. PubMed ID: 10913140
    [TBL] [Abstract][Full Text] [Related]  

  • 16. High Resolution Structures of the Human ABO(H) Blood Group Enzymes in Complex with Donor Analogs Reveal That the Enzymes Utilize Multiple Donor Conformations to Bind Substrates in a Stepwise Manner.
    Gagnon SML; Meloncelli PJ; Zheng RB; Haji-Ghassemi O; Johal AR; Borisova SN; Lowary TL; Evans SV
    J Biol Chem; 2015 Nov; 290(45):27040-27052. PubMed ID: 26374898
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Biosynthesis in vitro of neolactotetraosylceramide by a galactosyltransferase from mouse T-lymphoma: purification and kinetic studies; synthesis of neolacto and polylactosamine core.
    Basu M; Weng SA; Tang H; Khan F; Rossi F; Basu S
    Glycoconj J; 1996 Jun; 13(3):423-32. PubMed ID: 8781973
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Bovine mammary gland UDP-GalNAc:GlcNAcbeta-R beta1-->4-N-acetylgalactosaminyltransferase is glycoprotein hormone nonspecific and shows interaction with alpha-lactalbumin.
    Van den Nieuwenhof IM; Schiphorst WE; Van Die I; Van den Eijnden DH
    Glycobiology; 1999 Feb; 9(2):115-23. PubMed ID: 9949189
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Blood group B galactosyltransferase: insights into substrate binding from NMR experiments.
    Angulo J; Langpap B; Blume A; Biet T; Meyer B; Krishna NR; Peters H; Palcic MM; Peters T
    J Am Chem Soc; 2006 Oct; 128(41):13529-38. PubMed ID: 17031966
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Crystal structures of β-1,4-galactosyltransferase 7 enzyme reveal conformational changes and substrate binding.
    Tsutsui Y; Ramakrishnan B; Qasba PK
    J Biol Chem; 2013 Nov; 288(44):31963-70. PubMed ID: 24052259
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 17.