BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

190 related articles for article (PubMed ID: 11489946)

  • 1. Phosphoinositide 3-kinase-dependent membrane recruitment of p62(dok) is essential for its negative effect on mitogen-activated protein (MAP) kinase activation.
    Zhao M; Schmitz AA; Qin Y; Di Cristofano A; Pandolfi PP; Van Aelst L
    J Exp Med; 2001 Aug; 194(3):265-74. PubMed ID: 11489946
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Insulin receptor-mediated p62dok tyrosine phosphorylation at residues 362 and 398 plays distinct roles for binding GTPase-activating protein and Nck and is essential for inhibiting insulin-stimulated activation of Ras and Akt.
    Wick MJ; Dong LQ; Hu D; Langlais P; Liu F
    J Biol Chem; 2001 Nov; 276(46):42843-50. PubMed ID: 11551902
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Downstream of kinase, p62(dok), is a mediator of Fc gamma IIB inhibition of Fc epsilon RI signaling.
    Ott VL; Tamir I; Niki M; Pandolfi PP; Cambier JC
    J Immunol; 2002 May; 168(9):4430-9. PubMed ID: 11970986
    [TBL] [Abstract][Full Text] [Related]  

  • 4. p62(dok), a negative regulator of Ras and mitogen-activated protein kinase (MAPK) activity, opposes leukemogenesis by p210(bcr-abl).
    Di Cristofano A; Niki M; Zhao M; Karnell FG; Clarkson B; Pear WS; Van Aelst L; Pandolfi PP
    J Exp Med; 2001 Aug; 194(3):275-84. PubMed ID: 11489947
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Dok-1 independently attenuates Ras/mitogen-activated protein kinase and Src/c-myc pathways to inhibit platelet-derived growth factor-induced mitogenesis.
    Zhao M; Janas JA; Niki M; Pandolfi PP; Van Aelst L
    Mol Cell Biol; 2006 Apr; 26(7):2479-89. PubMed ID: 16537894
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Tyrosine phosphorylation of p62(Dok) induced by cell adhesion and insulin: possible role in cell migration.
    Noguchi T; Matozaki T; Inagaki K; Tsuda M; Fukunaga K; Kitamura Y; Kitamura T; Shii K; Yamanashi Y; Kasuga M
    EMBO J; 1999 Apr; 18(7):1748-60. PubMed ID: 10202139
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Phosphatidylinositol 3-kinase and Src family kinases are required for phosphorylation and membrane recruitment of Dok-1 in c-Kit signaling.
    Liang X; Wisniewski D; Strife A; Shivakrupa ; Clarkson B; Resh MD
    J Biol Chem; 2002 Apr; 277(16):13732-8. PubMed ID: 11825908
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Recruitment of Dok-R to the EGF receptor through its PTB domain is required for attenuation of Erk MAP kinase activation.
    Jones N; Dumont DJ
    Curr Biol; 1999 Sep; 9(18):1057-60. PubMed ID: 10508618
    [TBL] [Abstract][Full Text] [Related]  

  • 9. p62dok negatively regulates CD2 signaling in Jurkat cells.
    Némorin JG; Laporte P; Bérubé G; Duplay P
    J Immunol; 2001 Apr; 166(7):4408-15. PubMed ID: 11254695
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Characterization of a novel member of the DOK family that binds and modulates Abl signaling.
    Cong F; Yuan B; Goff SP
    Mol Cell Biol; 1999 Dec; 19(12):8314-25. PubMed ID: 10567556
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Stromal cell-derived factor-1alpha/CXCL12-induced chemotaxis of T cells involves activation of the RasGAP-associated docking protein p62Dok-1.
    Okabe S; Fukuda S; Kim YJ; Niki M; Pelus LM; Ohyashiki K; Pandolfi PP; Broxmeyer HE
    Blood; 2005 Jan; 105(2):474-80. PubMed ID: 15345598
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Evidence that Llck-mediated phosphorylation of p56dok and p62dok may play a role in CD2 signaling.
    Némorin JG; Duplay P
    J Biol Chem; 2000 May; 275(19):14590-7. PubMed ID: 10799545
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The rasGAP-binding protein, Dok-1, mediates activin signaling via serine/threonine kinase receptors.
    Yamakawa N; Tsuchida K; Sugino H
    EMBO J; 2002 Apr; 21(7):1684-94. PubMed ID: 11927552
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Dok-R mediates attenuation of epidermal growth factor-dependent mitogen-activated protein kinase and Akt activation through processive recruitment of c-Src and Csk.
    Van Slyke P; Coll ML; Master Z; Kim H; Filmus J; Dumont DJ
    Mol Cell Biol; 2005 May; 25(9):3831-41. PubMed ID: 15831486
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel p62dok family members, dok-4 and dok-5, are substrates of the c-Ret receptor tyrosine kinase and mediate neuronal differentiation.
    Grimm J; Sachs M; Britsch S; Di Cesare S; Schwarz-Romond T; Alitalo K; Birchmeier W
    J Cell Biol; 2001 Jul; 154(2):345-54. PubMed ID: 11470823
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Tyrosine phosphorylation of p62dok by p210bcr-abl inhibits RasGAP activity.
    Kashige N; Carpino N; Kobayashi R
    Proc Natl Acad Sci U S A; 2000 Feb; 97(5):2093-8. PubMed ID: 10688886
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Src family kinases mediate receptor-stimulated, phosphoinositide 3-kinase-dependent, tyrosine phosphorylation of dual adaptor for phosphotyrosine and 3-phosphoinositides-1 in endothelial and B cell lines.
    Stephens LR; Anderson KE; Hawkins PT
    J Biol Chem; 2001 Nov; 276(46):42767-73. PubMed ID: 11524430
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Pleckstrin homology and phosphotyrosine-binding domain-dependent membrane association and tyrosine phosphorylation of Dok-4, an inhibitory adapter molecule expressed in epithelial cells.
    Bedirian A; Baldwin C; Abe J; Takano T; Lemay S
    J Biol Chem; 2004 Apr; 279(18):19335-49. PubMed ID: 14963042
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Platelet-derived growth factor-dependent activation of phosphatidylinositol 3-kinase is regulated by receptor binding of SH2-domain-containing proteins which influence Ras activity.
    Klinghoffer RA; Duckworth B; Valius M; Cantley L; Kazlauskas A
    Mol Cell Biol; 1996 Oct; 16(10):5905-14. PubMed ID: 8816504
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Dok-R plays a pivotal role in angiopoietin-1-dependent cell migration through recruitment and activation of Pak.
    Master Z; Jones N; Tran J; Jones J; Kerbel RS; Dumont DJ
    EMBO J; 2001 Nov; 20(21):5919-28. PubMed ID: 11689432
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.