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3. Rifampin-induced release of hydrazine from isoniazid. A possible cause of hepatitis during treatment of tuberculosis with regimens containing isoniazid and rifampin. Sarma GR; Immanuel C; Kailasam S; Narayana AS; Venkatesan P Am Rev Respir Dis; 1986 Jun; 133(6):1072-5. PubMed ID: 3717759 [TBL] [Abstract][Full Text] [Related]
4. Pharmacokinetics of the toxic hydrazino metabolites formed from isoniazid in humans. Lauterburg BH; Smith CV; Todd EL; Mitchell JR J Pharmacol Exp Ther; 1985 Dec; 235(3):566-70. PubMed ID: 4078724 [TBL] [Abstract][Full Text] [Related]
5. Oxidation of hydrazine metabolites formed from isoniazid. Lauterburg BH; Smith CV; Todd EL; Mitchell JR Clin Pharmacol Ther; 1985 Nov; 38(5):566-71. PubMed ID: 3931954 [TBL] [Abstract][Full Text] [Related]
6. Monoacetylhydrazine as a metabolite of isoniazid in man. Timbrell JA; Wright JM; Baillie TA Clin Pharmacol Ther; 1977 Nov; 22(5 Pt 1):602-8. PubMed ID: 913027 [TBL] [Abstract][Full Text] [Related]
7. Increased urinary excretion of toxic hydrazino metabolites of isoniazid by slow acetylators. Effect of a slow-release preparation of isoniazid. Peretti E; Karlaganis G; Lauterburg BH Eur J Clin Pharmacol; 1987; 33(3):283-6. PubMed ID: 3691615 [TBL] [Abstract][Full Text] [Related]
8. [The potential clinical significance of the isoniazid acetylator phenotype in the treatment of pulmonary tuberculosis]. Ellard GA Rev Mal Respir; 1984; 1(4):207-19. PubMed ID: 6505358 [TBL] [Abstract][Full Text] [Related]
9. Acetylation of acetylhydrazine, the toxic metabolite of isoniazid, in humans. Inhibition by concomitant administration of isoniazid. Peretti E; Karlaganis G; Lauterburg BH J Pharmacol Exp Ther; 1987 Nov; 243(2):686-9. PubMed ID: 3681700 [TBL] [Abstract][Full Text] [Related]
10. Studies on the role of acetylhydrazine in isoniazid hepatotoxicity. Timbrell JA Arch Toxicol Suppl; 1979; (2):1-8. PubMed ID: 288324 [TBL] [Abstract][Full Text] [Related]
11. Polymorphism of the N-acetyltransferase 2 gene as a susceptibility risk factor for antituberculosis drug-induced hepatitis. Huang YS; Chern HD; Su WJ; Wu JC; Lai SL; Yang SY; Chang FY; Lee SD Hepatology; 2002 Apr; 35(4):883-9. PubMed ID: 11915035 [TBL] [Abstract][Full Text] [Related]
12. Studies on the effects of isoniazid on acetylhydrazine metabolism in vivo and in vitro. Timbrell JA; Wright JM Drug Metab Dispos; 1979; 7(4):237-40. PubMed ID: 39727 [TBL] [Abstract][Full Text] [Related]
13. Predisposing factors in hepatitis induced by isoniazid-rifampin treatment of tuberculosis. Grönhagen-Riska C; Hellstrom PE; Fröseth B Am Rev Respir Dis; 1978 Sep; 118(3):461-6. PubMed ID: 707874 [TBL] [Abstract][Full Text] [Related]
14. [Incidence of hepatotoxic side effects during antituberculous therapy (INH, RMP, EMB) in relation to the acetylator phenotype (author's transl)]. Musch E; Eichelbaum M; Wang JK; von Sassen W; Castro-Parra M; Dengler HJ Klin Wochenschr; 1982 May; 60(10):513-9. PubMed ID: 7098379 [TBL] [Abstract][Full Text] [Related]
15. Isoniazid and iproniazid: activation of metabolites to toxic intermediates in man and rat. Nelson SD; Mitchell JR; Timbrell JA; Snodgrass WR; Corcoran GB Science; 1976 Sep; 193(4256):901-3. PubMed ID: 7838 [TBL] [Abstract][Full Text] [Related]
16. Factors affecting the metabolism of [14C]acetylhydrazine in rats. Wright JM; Timbrell JA Drug Metab Dispos; 1978; 6(5):561-6. PubMed ID: 30606 [TBL] [Abstract][Full Text] [Related]