150 related articles for article (PubMed ID: 11501996)
1. Folate-binding triggers the activation of folylpolyglutamate synthetase.
Sun X; Cross JA; Bognar AL; Baker EN; Smith CA
J Mol Biol; 2001 Jul; 310(5):1067-78. PubMed ID: 11501996
[TBL] [Abstract][Full Text] [Related]
2. Structural and functional similarities in the ADP-forming amide bond ligase superfamily: implications for a substrate-induced conformational change in folylpolyglutamate synthetase.
Sheng Y; Sun X; Shen Y; Bognar AL; Baker EN; Smith CA
J Mol Biol; 2000 Sep; 302(2):427-40. PubMed ID: 10970743
[TBL] [Abstract][Full Text] [Related]
3. Binding of ATP as well as tetrahydrofolate induces conformational changes in Lactobacillus casei folylpolyglutamate synthetase in solution.
Sheng Y; Ip H; Liu J; Davidson A; Bognar AL
Biochemistry; 2003 Feb; 42(6):1537-43. PubMed ID: 12578366
[TBL] [Abstract][Full Text] [Related]
4. Structural homologies with ATP- and folate-binding enzymes in the crystal structure of folylpolyglutamate synthetase.
Sun X; Bognar AL; Baker EN; Smith CA
Proc Natl Acad Sci U S A; 1998 Jun; 95(12):6647-52. PubMed ID: 9618466
[TBL] [Abstract][Full Text] [Related]
5. Mutagenesis of folylpolyglutamate synthetase indicates that dihydropteroate and tetrahydrofolate bind to the same site.
Sheng Y; Khanam N; Tsaksis Y; Shi XM; Lu QS; Bognar AL
Biochemistry; 2008 Feb; 47(8):2388-96. PubMed ID: 18232714
[TBL] [Abstract][Full Text] [Related]
6. Mutation of an essential glutamate residue in folylpolyglutamate synthetase and activation of the enzyme by pteroate binding.
Sheng Y; Cross JA; Shen Y; Smith CA; Bognar AL
Arch Biochem Biophys; 2002 Jun; 402(1):94-103. PubMed ID: 12051687
[TBL] [Abstract][Full Text] [Related]
7. Mutation of Gly51 to serine in the P-loop of Lactobacillus casei folylpolyglutamate synthetase abolishes activity by altering the conformation of two adjacent loops.
Smith CA; Cross JA; Bognar AL; Sun X
Acta Crystallogr D Biol Crystallogr; 2006 May; 62(Pt 5):548-58. PubMed ID: 16627949
[TBL] [Abstract][Full Text] [Related]
8. Docking studies and ligand recognition in folylpolyglutamate synthetase.
Tan XJ; Carlson HA
J Med Chem; 2005 Dec; 48(24):7764-72. PubMed ID: 16302815
[TBL] [Abstract][Full Text] [Related]
9. Folylpoly-γ-glutamate synthetase: A key determinant of folate homeostasis and antifolate resistance in cancer.
Raz S; Stark M; Assaraf YG
Drug Resist Updat; 2016 Sep; 28():43-64. PubMed ID: 27620954
[TBL] [Abstract][Full Text] [Related]
10. Structures of Mycobacterium tuberculosis folylpolyglutamate synthase complexed with ADP and AMPPCP.
Young PG; Smith CA; Metcalf P; Baker EN
Acta Crystallogr D Biol Crystallogr; 2008 Jul; D64(Pt 7):745-53. PubMed ID: 18566510
[TBL] [Abstract][Full Text] [Related]
11. Molecular analysis of murine leukemia cell lines resistant to 5, 10-dideazatetrahydrofolate identifies several amino acids critical to the function of folylpolyglutamate synthetase.
Zhao R; Titus S; Gao F; Moran RG; Goldman ID
J Biol Chem; 2000 Aug; 275(34):26599-606. PubMed ID: 10856298
[TBL] [Abstract][Full Text] [Related]
12. Regulation of folate and one-carbon metabolism in mammalian cells. I. Folate metabolism in Chinese hamster ovary cells expressing Escherichia coli or human folylpoly-gamma-glutamate synthetase activity.
Osborne CB; Lowe KE; Shane B
J Biol Chem; 1993 Oct; 268(29):21657-64. PubMed ID: 8408018
[TBL] [Abstract][Full Text] [Related]
13. Loss of folylpoly-gamma-glutamate synthetase activity is a dominant mechanism of resistance to polyglutamylation-dependent novel antifolates in multiple human leukemia sublines.
Liani E; Rothem L; Bunni MA; Smith CA; Jansen G; Assaraf YG
Int J Cancer; 2003 Feb; 103(5):587-99. PubMed ID: 12494465
[TBL] [Abstract][Full Text] [Related]
14. Mutagenesis of the Lactobacillus casei folylpolyglutamate synthetase gene at essential residues resembling an ATP binding site.
Toy J; Bognar AL
Arch Biochem Biophys; 1994 Nov; 314(2):344-50. PubMed ID: 7979375
[TBL] [Abstract][Full Text] [Related]
15. Purification and properties of Lactobacillus casei folylpoly-gamma-glutamate synthetase.
Bognar AL; Shane B
J Biol Chem; 1983 Oct; 258(20):12574-81. PubMed ID: 6138353
[TBL] [Abstract][Full Text] [Related]
16. Characterization of the folylpolyglutamate synthetase gene and polyglutamylation of folates in the protozoan parasite Leishmania.
El Fadili A; Kündig C; Ouellette M
Mol Biochem Parasitol; 2002; 124(1-2):63-71. PubMed ID: 12387851
[TBL] [Abstract][Full Text] [Related]
17. Cloning and expression of the gene encoding Lactobacillus casei folylpoly-gamma-glutamate synthetase in Escherichia coli and determination of its primary structure.
Toy J; Bognar AL
J Biol Chem; 1990 Feb; 265(5):2492-9. PubMed ID: 2105929
[TBL] [Abstract][Full Text] [Related]
18. Regulation of folate and one-carbon metabolism in mammalian cells. II. Effect of folylpoly-gamma-glutamate synthetase substrate specificity and level on folate metabolism and folylpoly-gamma-glutamate specificity of metabolic cycles of one-carbon metabolism.
Lowe KE; Osborne CB; Lin BF; Kim JS; Hsu JC; Shane B
J Biol Chem; 1993 Oct; 268(29):21665-73. PubMed ID: 8408019
[TBL] [Abstract][Full Text] [Related]
19. A strategy for the design of membrane-permeable folypoly-gamma-glutamate synthetase inhibitors: "bay-region"-substituted 2-desamino-2-methyl-5,8-dideazafolate analogs.
Sanghani PC; Jackman A; Evans VR; Thornton T; Hughes L; Calvert AH; Moran RG
Mol Pharmacol; 1994 Feb; 45(2):341-51. PubMed ID: 8114682
[TBL] [Abstract][Full Text] [Related]
20. Characterisation of the bifunctional dihydrofolate synthase-folylpolyglutamate synthase from Plasmodium falciparum; a potential novel target for antimalarial antifolate inhibition.
Wang P; Wang Q; Yang Y; Coward JK; Nzila A; Sims PF; Hyde JE
Mol Biochem Parasitol; 2010 Jul; 172(1):41-51. PubMed ID: 20350571
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
