486 related articles for article (PubMed ID: 11502872)
1. Regulation of the human CYP2B6 gene by the nuclear pregnane X receptor.
Goodwin B; Moore LB; Stoltz CM; McKee DD; Kliewer SA
Mol Pharmacol; 2001 Sep; 60(3):427-31. PubMed ID: 11502872
[TBL] [Abstract][Full Text] [Related]
2. A novel distal enhancer module regulated by pregnane X receptor/constitutive androstane receptor is essential for the maximal induction of CYP2B6 gene expression.
Wang H; Faucette S; Sueyoshi T; Moore R; Ferguson S; Negishi M; LeCluyse EL
J Biol Chem; 2003 Apr; 278(16):14146-52. PubMed ID: 12571232
[TBL] [Abstract][Full Text] [Related]
3. Glucocorticoid receptor enhancement of pregnane X receptor-mediated CYP2B6 regulation in primary human hepatocytes.
Wang H; Faucette SR; Gilbert D; Jolley SL; Sueyoshi T; Negishi M; LeCluyse EL
Drug Metab Dispos; 2003 May; 31(5):620-30. PubMed ID: 12695351
[TBL] [Abstract][Full Text] [Related]
4. Differential regulation of hepatic CYP2B6 and CYP3A4 genes by constitutive androstane receptor but not pregnane X receptor.
Faucette SR; Sueyoshi T; Smith CM; Negishi M; Lecluyse EL; Wang H
J Pharmacol Exp Ther; 2006 Jun; 317(3):1200-9. PubMed ID: 16513849
[TBL] [Abstract][Full Text] [Related]
5. PXR, CAR and drug metabolism.
Willson TM; Kliewer SA
Nat Rev Drug Discov; 2002 Apr; 1(4):259-66. PubMed ID: 12120277
[TBL] [Abstract][Full Text] [Related]
6. Human constitutive androstane receptor mediates induction of CYP2B6 gene expression by phenytoin.
Wang H; Faucette S; Moore R; Sueyoshi T; Negishi M; LeCluyse E
J Biol Chem; 2004 Jul; 279(28):29295-301. PubMed ID: 15123723
[TBL] [Abstract][Full Text] [Related]
7. The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism.
Kliewer SA; Goodwin B; Willson TM
Endocr Rev; 2002 Oct; 23(5):687-702. PubMed ID: 12372848
[TBL] [Abstract][Full Text] [Related]
8. Valproic acid induces CYP3A4 and MDR1 gene expression by activation of constitutive androstane receptor and pregnane X receptor pathways.
Cerveny L; Svecova L; Anzenbacherova E; Vrzal R; Staud F; Dvorak Z; Ulrichova J; Anzenbacher P; Pavek P
Drug Metab Dispos; 2007 Jul; 35(7):1032-41. PubMed ID: 17392393
[TBL] [Abstract][Full Text] [Related]
9. Dexamethasone enhances constitutive androstane receptor expression in human hepatocytes: consequences on cytochrome P450 gene regulation.
Pascussi JM; Gerbal-Chaloin S; Fabre JM; Maurel P; Vilarem MJ
Mol Pharmacol; 2000 Dec; 58(6):1441-50. PubMed ID: 11093784
[TBL] [Abstract][Full Text] [Related]
10. Orphan nuclear receptor binding site in the human inducible nitric oxide synthase promoter mediates responsiveness to steroid and xenobiotic ligands.
Toell A; Kröncke KD; Kleinert H; Carlberg C
J Cell Biochem; 2002; 85(1):72-82. PubMed ID: 11891851
[TBL] [Abstract][Full Text] [Related]
11. The induction of human UDP-glucuronosyltransferase 1A1 mediated through a distal enhancer module by flavonoids and xenobiotics.
Sugatani J; Yamakawa K; Tonda E; Nishitani S; Yoshinari K; Degawa M; Abe I; Noguchi H; Miwa M
Biochem Pharmacol; 2004 Mar; 67(5):989-1000. PubMed ID: 15104253
[TBL] [Abstract][Full Text] [Related]
12. Endosulfan induces CYP2B6 and CYP3A4 by activating the pregnane X receptor.
Casabar RC; Das PC; Dekrey GK; Gardiner CS; Cao Y; Rose RL; Wallace AD
Toxicol Appl Pharmacol; 2010 Jun; 245(3):335-43. PubMed ID: 20361990
[TBL] [Abstract][Full Text] [Related]
13. Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands.
Moore LB; Parks DJ; Jones SA; Bledsoe RK; Consler TG; Stimmel JB; Goodwin B; Liddle C; Blanchard SG; Willson TM; Collins JL; Kliewer SA
J Biol Chem; 2000 May; 275(20):15122-7. PubMed ID: 10748001
[TBL] [Abstract][Full Text] [Related]
14. Regulation of cytochrome P450 2C9 expression in primary cultures of human hepatocytes.
Sahi J; Shord SS; Lindley C; Ferguson S; LeCluyse EL
J Biochem Mol Toxicol; 2009; 23(1):43-58. PubMed ID: 19202563
[TBL] [Abstract][Full Text] [Related]
15. Transcriptional regulation of cytochrome p450 2B genes by nuclear receptors.
Wang H; Negishi M
Curr Drug Metab; 2003 Dec; 4(6):515-25. PubMed ID: 14683479
[TBL] [Abstract][Full Text] [Related]
16. Human CYP2C8 is transcriptionally regulated by the nuclear receptors constitutive androstane receptor, pregnane X receptor, glucocorticoid receptor, and hepatic nuclear factor 4alpha.
Ferguson SS; Chen Y; LeCluyse EL; Negishi M; Goldstein JA
Mol Pharmacol; 2005 Sep; 68(3):747-57. PubMed ID: 15933212
[TBL] [Abstract][Full Text] [Related]
17. Relative activation of human pregnane X receptor versus constitutive androstane receptor defines distinct classes of CYP2B6 and CYP3A4 inducers.
Faucette SR; Zhang TC; Moore R; Sueyoshi T; Omiecinski CJ; LeCluyse EL; Negishi M; Wang H
J Pharmacol Exp Ther; 2007 Jan; 320(1):72-80. PubMed ID: 17041008
[TBL] [Abstract][Full Text] [Related]
18. Reciprocal activation of xenobiotic response genes by nuclear receptors SXR/PXR and CAR.
Xie W; Barwick JL; Simon CM; Pierce AM; Safe S; Blumberg B; Guzelian PS; Evans RM
Genes Dev; 2000 Dec; 14(23):3014-23. PubMed ID: 11114890
[TBL] [Abstract][Full Text] [Related]
19. The expression of CYP2B6, CYP2C9 and CYP3A4 genes: a tangle of networks of nuclear and steroid receptors.
Pascussi JM; Gerbal-Chaloin S; Drocourt L; Maurel P; Vilarem MJ
Biochim Biophys Acta; 2003 Feb; 1619(3):243-53. PubMed ID: 12573484
[TBL] [Abstract][Full Text] [Related]
20. A human immunodeficiency virus protease inhibitor is a novel functional inhibitor of human pregnane X receptor.
Healan-Greenberg C; Waring JF; Kempf DJ; Blomme EA; Tirona RG; Kim RB
Drug Metab Dispos; 2008 Mar; 36(3):500-7. PubMed ID: 18096673
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
