BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

261 related articles for article (PubMed ID: 11504919)

  • 1. Intravenous administration of MEK inhibitor U0126 affords brain protection against forebrain ischemia and focal cerebral ischemia.
    Namura S; Iihara K; Takami S; Nagata I; Kikuchi H; Matsushita K; Moskowitz MA; Bonventre JV; Alessandrini A
    Proc Natl Acad Sci U S A; 2001 Sep; 98(20):11569-74. PubMed ID: 11504919
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Inhibition of the MEK/ERK pathway reduces microglial activation and interleukin-1-beta expression in spinal cord ischemia/reperfusion injury in rats.
    Lu K; Cho CL; Liang CL; Chen SD; Liliang PC; Wang SY; Chen HJ
    J Thorac Cardiovasc Surg; 2007 Apr; 133(4):934-41. PubMed ID: 17382630
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Inhibition of MEK/ERK 1/2 pathway reduces pro-inflammatory cytokine interleukin-1 expression in focal cerebral ischemia.
    Wang ZQ; Wu DC; Huang FP; Yang GY
    Brain Res; 2004 Jan; 996(1):55-66. PubMed ID: 14670631
    [TBL] [Abstract][Full Text] [Related]  

  • 4. U0126 attenuates ischemia/reperfusion-induced apoptosis and autophagy in myocardium through MEK/ERK/EGR-1 pathway.
    Wang A; Zhang H; Liang Z; Xu K; Qiu W; Tian Y; Guo H; Jia J; Xing E; Chen R; Xiang Z; Liu J
    Eur J Pharmacol; 2016 Oct; 788():280-285. PubMed ID: 27343376
    [TBL] [Abstract][Full Text] [Related]  

  • 5. MEK-inhibitor U0126 in hyperglycaemic focal ischaemic brain injury in the rat.
    Farrokhnia N; Ericsson A; Terént A; Lennmyr F
    Eur J Clin Invest; 2008 Sep; 38(9):679-85. PubMed ID: 18837745
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Activation of ERK accelerates repair of renal tubular epithelial cells, whereas it inhibits progression of fibrosis following ischemia/reperfusion injury.
    Jang HS; Han SJ; Kim JI; Lee S; Lipschutz JH; Park KM
    Biochim Biophys Acta; 2013 Dec; 1832(12):1998-2008. PubMed ID: 23851027
    [TBL] [Abstract][Full Text] [Related]  

  • 7. ABCG2 protects kidney side population cells from hypoxia/reoxygenation injury through activation of the MEK/ERK pathway.
    Liu WH; Liu HB; Gao DK; Ge GQ; Zhang P; Sun SR; Wang HM; Liu SB
    Cell Transplant; 2013; 22(10):1859-68. PubMed ID: 23032069
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Increased expression of glucose transporter 3 in gerbil brains following magnesium sulfate treatment and focal cerebral ischemic injury.
    Huang CY; Liou YF; Chung SY; Pai PY; Kan CB; Kuo CH; Tsai CH; Tsai FJ; Chen JL; Lin JY
    Cell Biochem Funct; 2010 Jun; 28(4):313-20. PubMed ID: 20517896
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Importance of MEK-1/-2 signaling in monocytic and granulocytic differentiation of myeloid cell lines.
    Miranda MB; McGuire TF; Johnson DE
    Leukemia; 2002 Apr; 16(4):683-92. PubMed ID: 11960350
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Neuroprotective effect of sodium orthovanadate on delayed neuronal death after transient forebrain ischemia in gerbil hippocampus.
    Kawano T; Fukunaga K; Takeuchi Y; Morioka M; Yano S; Hamada J; Ushio Y; Miyamoto E
    J Cereb Blood Flow Metab; 2001 Nov; 21(11):1268-80. PubMed ID: 11702042
    [TBL] [Abstract][Full Text] [Related]  

  • 11. MEK inhibitor U0126 interferes with immunofluorescence analysis of apoptotic cell death.
    Blank N; Burger R; Duerr B; Bakker F; Wohlfarth A; Dumitriu I; Kalden JR; Herrmann M
    Cytometry; 2002 Aug; 48(4):179-84. PubMed ID: 12210141
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Significant neuroprotection against ischemic brain injury by inhibition of the MEK1 protein kinase in mice: exploration of potential mechanism associated with apoptosis.
    Wang X; Wang H; Xu L; Rozanski DJ; Sugawara T; Chan PH; Trzaskos JM; Feuerstein GZ
    J Pharmacol Exp Ther; 2003 Jan; 304(1):172-8. PubMed ID: 12490588
    [TBL] [Abstract][Full Text] [Related]  

  • 13. U0126 prevents ERK pathway phosphorylation and interleukin-1beta mRNA production after cerebral ischemia.
    Wang ZQ; Chen XC; Yang GY; Zhou LF
    Chin Med Sci J; 2004 Dec; 19(4):270-5. PubMed ID: 15669185
    [TBL] [Abstract][Full Text] [Related]  

  • 14. A neuroprotective role of extracellular signal-regulated kinase in N-acetyl-O-methyldopamine-treated hippocampal neurons after exposure to in vitro and in vivo ischemia.
    Park EM; Joh TH; Volpe BT; Chu CK; Song G; Cho S
    Neuroscience; 2004; 123(1):147-54. PubMed ID: 14667449
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Role of the activated extracellular signal-regulated kinase pathway on histological and behavioral outcome after traumatic brain injury in rats.
    Otani N; Nawashiro H; Fukui S; Ooigawa H; Ohsumi A; Toyooka T; Shima K
    J Clin Neurosci; 2007 Jan; 14(1):42-8. PubMed ID: 17138068
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Both PI3K/Akt and ERK1/2 pathways participate in the protection by dexmedetomidine against transient focal cerebral ischemia/reperfusion injury in rats.
    Zhu YM; Wang CC; Chen L; Qian LB; Ma LL; Yu J; Zhu MH; Wen CY; Yu LN; Yan M
    Brain Res; 2013 Feb; 1494():1-8. PubMed ID: 23219579
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Activation of Akt/FoxO and inactivation of MEK/ERK pathways contribute to induction of neuroprotection against transient global cerebral ischemia by delayed hypoxic postconditioning in adult rats.
    Zhan L; Li D; Liang D; Wu B; Zhu P; Wang Y; Sun W; Xu E
    Neuropharmacology; 2012 Oct; 63(5):873-82. PubMed ID: 22749925
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Neuroprotective effect of WIN 55,212-2 pretreatment against focal cerebral ischemia through activation of extracellular signal-regulated kinases in rats.
    Hu B; Wang Q; Chen Y; Du J; Zhu X; Lu Y; Xiong L; Chen S
    Eur J Pharmacol; 2010 Oct; 645(1-3):102-7. PubMed ID: 20667450
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Inhibition of MAP kinase kinase (MEK) results in an anti-inflammatory response in vivo.
    Jaffee BD; Manos EJ; Collins RJ; Czerniak PM; Favata MF; Magolda RL; Scherle PA; Trzaskos JM
    Biochem Biophys Res Commun; 2000 Feb; 268(2):647-51. PubMed ID: 10679258
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Extracellular signal-regulated kinase activation during renal ischemia/reperfusion mediates focal adhesion dissolution and renal injury.
    Alderliesten M; de Graauw M; Oldenampsen J; Qin Y; Pont C; van Buren L; van de Water B
    Am J Pathol; 2007 Aug; 171(2):452-62. PubMed ID: 17620366
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 14.