114 related articles for article (PubMed ID: 11507069)
1. A novel cdk2-selective inhibitor, SU9516, induces apoptosis in colon carcinoma cells.
Lane ME; Yu B; Rice A; Lipson KE; Liang C; Sun L; Tang C; McMahon G; Pestell RG; Wadler S
Cancer Res; 2001 Aug; 61(16):6170-7. PubMed ID: 11507069
[TBL] [Abstract][Full Text] [Related]
2. SU9516, a cyclin-dependent kinase 2 inhibitor, promotes accumulation of high molecular weight E2F complexes in human colon carcinoma cells.
Yu B; Lane ME; Wadler S
Biochem Pharmacol; 2002 Oct; 64(7):1091-100. PubMed ID: 12234612
[TBL] [Abstract][Full Text] [Related]
3. The three-substituted indolinone cyclin-dependent kinase 2 inhibitor 3-[1-(3H-imidazol-4-yl)-meth-(Z)-ylidene]-5-methoxy-1,3-dihydro-indol-2-one (SU9516) kills human leukemia cells via down-regulation of Mcl-1 through a transcriptional mechanism.
Gao N; Kramer L; Rahmani M; Dent P; Grant S
Mol Pharmacol; 2006 Aug; 70(2):645-55. PubMed ID: 16672643
[TBL] [Abstract][Full Text] [Related]
4. Transforming growth factor beta 1 increases the stability of p21/WAF1/CIP1 protein and inhibits CDK2 kinase activity in human colon carcinoma FET cells.
Gong J; Ammanamanchi S; Ko TC; Brattain MG
Cancer Res; 2003 Jun; 63(12):3340-6. PubMed ID: 12810668
[TBL] [Abstract][Full Text] [Related]
5. Cyclin E-cdk2 activation is associated with cell cycle arrest and inhibition of DNA replication induced by the thymidylate synthase inhibitor Tomudex.
Yin MB; Guo B; Panadero A; Frank C; Wrzosek C; Slocum HK; Rustum YM
Exp Cell Res; 1999 Feb; 247(1):189-99. PubMed ID: 10047461
[TBL] [Abstract][Full Text] [Related]
6. Flavopiridol induces G1 arrest with inhibition of cyclin-dependent kinase (CDK) 2 and CDK4 in human breast carcinoma cells.
Carlson BA; Dubay MM; Sausville EA; Brizuela L; Worland PJ
Cancer Res; 1996 Jul; 56(13):2973-8. PubMed ID: 8674031
[TBL] [Abstract][Full Text] [Related]
7. Flavopiridol, a novel cyclin-dependent kinase inhibitor, suppresses the growth of head and neck squamous cell carcinomas by inducing apoptosis.
Patel V; Senderowicz AM; Pinto D; Igishi T; Raffeld M; Quintanilla-Martinez L; Ensley JF; Sausville EA; Gutkind JS
J Clin Invest; 1998 Nov; 102(9):1674-81. PubMed ID: 9802881
[TBL] [Abstract][Full Text] [Related]
8. Downregulation of cyclin D1 alters cdk 4- and cdk 2-specific phosphorylation of retinoblastoma protein.
Yu B; Lane ME; Pestell RG; Albanese C; Wadler S
Mol Cell Biol Res Commun; 2000 Jun; 3(6):352-9. PubMed ID: 11032757
[TBL] [Abstract][Full Text] [Related]
9. Inhibition of cyclin-dependent kinases 2 and 4 activities as well as induction of Cdk inhibitors p21 and p27 during growth arrest of human breast carcinoma cells by (-)-epigallocatechin-3-gallate.
Liang YC; Lin-Shiau SY; Chen CF; Lin JK
J Cell Biochem; 1999 Oct; 75(1):1-12. PubMed ID: 10462699
[TBL] [Abstract][Full Text] [Related]
10. NA22598, a novel antitumor compound, reduces cyclin D1 levels, arrests cell cycle at G1 phase, and inhibits anchorage-independent growth of human tumor cells.
Kawada M; Kuwahara A; Nishikiori T; Mizuno S; Uehara Y
Exp Cell Res; 1999 Jun; 249(2):240-7. PubMed ID: 10366423
[TBL] [Abstract][Full Text] [Related]
11. CaMK-II inhibition reduces cyclin D1 levels and enhances the association of p27kip1 with Cdk2 to cause G1 arrest in NIH 3T3 cells.
Morris TA; DeLorenzo RJ; Tombes RM
Exp Cell Res; 1998 May; 240(2):218-27. PubMed ID: 9596994
[TBL] [Abstract][Full Text] [Related]
12. Monensin-mediated growth inhibition of SNU-C1 colon cancer cells via cell cycle arrest and apoptosis.
Park WH; Kim ES; Jung CW; Kim BK; Lee YY
Int J Oncol; 2003 Feb; 22(2):377-82. PubMed ID: 12527937
[TBL] [Abstract][Full Text] [Related]
13. Selective sensitization of retinoblastoma protein-deficient sarcoma cells to doxorubicin by flavopiridol-mediated inhibition of cyclin-dependent kinase 2 kinase activity.
Li W; Fan J; Bertino JR
Cancer Res; 2001 Mar; 61(6):2579-82. PubMed ID: 11289134
[TBL] [Abstract][Full Text] [Related]
14. Flavopiridol, a cyclin-dependent kinase inhibitor, prevents spindle inhibitor-induced endoreduplication in human cancer cells.
Motwani M; Li X; Schwartz GK
Clin Cancer Res; 2000 Mar; 6(3):924-32. PubMed ID: 10741717
[TBL] [Abstract][Full Text] [Related]
15. Lycopene inhibition of cell cycle progression in breast and endometrial cancer cells is associated with reduction in cyclin D levels and retention of p27(Kip1) in the cyclin E-cdk2 complexes.
Nahum A; Hirsch K; Danilenko M; Watts CK; Prall OW; Levy J; Sharoni Y
Oncogene; 2001 Jun; 20(26):3428-36. PubMed ID: 11423993
[TBL] [Abstract][Full Text] [Related]
16. pRb and Cdk regulation by N-(4-hydroxyphenyl)retinamide.
Panigone S; Debernardi S; Taya Y; Fontanella E; Airoldi R; Delia D
Oncogene; 2000 Aug; 19(35):4035-41. PubMed ID: 10962560
[TBL] [Abstract][Full Text] [Related]
17. K252a inhibits the phosphorylation of pRb without changing the levels of G1 cyclins and Cdk2 protein in human hepatoma cells.
Nakayama T; Hashimoto Y; Kaneko Y; Kurokawa K
Biochem Biophys Res Commun; 1996 Jul; 224(1):180-3. PubMed ID: 8694809
[TBL] [Abstract][Full Text] [Related]
18. Lymphoma models for B-cell activation and tolerance: anti-immunoglobulin M treatment induces growth arrest by preventing the formation of an active kinase complex which phosphorylates retinoblastoma gene product in G1.
Joseph LF; Ezhevsky S; Scott DW
Cell Growth Differ; 1995 Jan; 6(1):51-7. PubMed ID: 7718485
[TBL] [Abstract][Full Text] [Related]
19. Inhibitors of histone deacetylase arrest cell cycle and induce apoptosis in cervical carcinoma cells circumventing human papillomavirus oncogene expression.
Finzer P; Kuntzen C; Soto U; zur Hausen H; Rösl F
Oncogene; 2001 Aug; 20(35):4768-76. PubMed ID: 11521189
[TBL] [Abstract][Full Text] [Related]
20. Increased cdc2 and cdk2 kinase activity by retinoid X receptor gamma-mediated transcriptional down-regulation of the cyclin-dependent kinase inhibitor p21Cip1/WAF1 correlates with terminal differentiation of squamous cell carcinoma lines.
Crowe DL; Shuler CF
Cell Growth Differ; 1998 Aug; 9(8):619-27. PubMed ID: 9716179
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
