157 related articles for article (PubMed ID: 11507714)
21. The contribution of intestinal UDP-glucuronosyltransferases in modulating 7-ethyl-10-hydroxy-camptothecin (SN-38)-induced gastrointestinal toxicity in rats.
Tallman MN; Miles KK; Kessler FK; Nielsen JN; Tian X; Ritter JK; Smith PC
J Pharmacol Exp Ther; 2007 Jan; 320(1):29-37. PubMed ID: 17003228
[TBL] [Abstract][Full Text] [Related]
22. Genetic predisposition to the metabolism of irinotecan (CPT-11). Role of uridine diphosphate glucuronosyltransferase isoform 1A1 in the glucuronidation of its active metabolite (SN-38) in human liver microsomes.
Iyer L; King CD; Whitington PF; Green MD; Roy SK; Tephly TR; Coffman BL; Ratain MJ
J Clin Invest; 1998 Feb; 101(4):847-54. PubMed ID: 9466980
[TBL] [Abstract][Full Text] [Related]
23. The novel UGT1A9 intronic I399 polymorphism appears as a predictor of 7-ethyl-10-hydroxycamptothecin glucuronidation levels in the liver.
Girard H; Villeneuve L; Court MH; Fortier LC; Caron P; Hao Q; von Moltke LL; Greenblatt DJ; Guillemette C
Drug Metab Dispos; 2006 Jul; 34(7):1220-8. PubMed ID: 16595709
[TBL] [Abstract][Full Text] [Related]
24. Development and validation of reversed phase liquid chromatographic method utilizing ultraviolet detection for quantification of irinotecan (CPT-11) and its active metabolite, SN-38, in rat plasma and bile samples: application to pharmacokinetic studies.
Bansal T; Awasthi A; Jaggi M; Khar RK; Talegaonkar S
Talanta; 2008 Sep; 76(5):1015-21. PubMed ID: 18761148
[TBL] [Abstract][Full Text] [Related]
25. Development and validation of an UPLC-MS/MS method for the determination of irinotecan (CPT-11), SN-38 and SN-38 glucuronide in human plasma and peritoneal tumor tissue from patients with peritoneal carcinomatosis.
Gasthuys E; van Ovost J; Vande Casteele S; Cosyns S; Ceelen W; Van Bocxlaer J; Vermeulen A
J Chromatogr B Analyt Technol Biomed Life Sci; 2024 Feb; 1233():123980. PubMed ID: 38215697
[TBL] [Abstract][Full Text] [Related]
26. Glucuronidation of 1-hydroxypyrene by human liver microsomes and human UDP-glucuronosyltransferases UGT1A6, UGT1A7, and UGT1A9: development of a high-sensitivity glucuronidation assay for human tissue.
Luukkanen L; Mikkola J; Forsman T; Taavitsainen P; Taskinen J; Elovaara E
Drug Metab Dispos; 2001 Aug; 29(8):1096-101. PubMed ID: 11454727
[TBL] [Abstract][Full Text] [Related]
27. UGT1A10 is responsible for SN-38 glucuronidation and its expression in human lung cancers.
Oguri T; Takahashi T; Miyazaki M; Isobe T; Kohno N; Mackenzie PI; Fujiwara Y
Anticancer Res; 2004; 24(5A):2893-6. PubMed ID: 15517893
[TBL] [Abstract][Full Text] [Related]
28. Sensitive liquid chromatographic method using fluorescence detection for the determination of estradiol 3- and 17-glucuronides in rat and human liver microsomal incubations: formation kinetics.
Alkharfy KM; Frye RF
J Chromatogr B Analyt Technol Biomed Life Sci; 2002 Jul; 774(1):33-8. PubMed ID: 12052720
[TBL] [Abstract][Full Text] [Related]
29. Determination by liquid chromatography with fluorescence detection of total 7-ethyl-10-hydroxy-camptothecin (SN-38) in beagle dog plasma after intravenous administration of liposome-based SN-38 (LE-SN38).
Guo W; Ahmad A; Khan S; Dahhani F; Wang YF; Ahmad I
J Chromatogr B Analyt Technol Biomed Life Sci; 2003 Jul; 791(1-2):85-92. PubMed ID: 12798168
[TBL] [Abstract][Full Text] [Related]
30. Quantitation of Irinotecan and its two major metabolites using a liquid chromatography-electrospray ionization tandem mass spectrometric.
Zhang W; Dutschman GE; Li X; Ye M; Cheng YC
J Chromatogr B Analyt Technol Biomed Life Sci; 2009 Oct; 877(27):3038-44. PubMed ID: 19648066
[TBL] [Abstract][Full Text] [Related]
31. Development and validation of a reverse-phase HPLC with fluorescence detector method for simultaneous determination of CZ48 and its active metabolite camptothecin in mouse plasma.
Liu X; Wang Y; Vardeman D; Cao Z; Giovanella B
J Chromatogr B Analyt Technol Biomed Life Sci; 2008 May; 867(1):84-9. PubMed ID: 18396471
[TBL] [Abstract][Full Text] [Related]
32. Ultra-performance liquid chromatographic-electrospray mass spectrometric determination (UPLC-ESI-MS) of O-demethylated metabolite of paeonol in vitro: assay development, human liver microsome activities and species differences.
Liu HX; Hu Y; He YQ; Liu Y; Li W; Yang L
Talanta; 2009 Oct; 79(5):1433-40. PubMed ID: 19635381
[TBL] [Abstract][Full Text] [Related]
33. Effects of ketoconazole on glucuronidation by UDP-glucuronosyltransferase enzymes.
Yong WP; Ramirez J; Innocenti F; Ratain MJ
Clin Cancer Res; 2005 Sep; 11(18):6699-704. PubMed ID: 16166450
[TBL] [Abstract][Full Text] [Related]
34. Glucuronidation of SN-38, the active metabolite of irinotecan, by human hepatic microsomes.
Haaz MC; Rivory L; Jantet S; Ratanasavanh D; Robert J
Pharmacol Toxicol; 1997 Feb; 80(2):91-6. PubMed ID: 9060040
[TBL] [Abstract][Full Text] [Related]
35. High-performance liquid chromatographic method combining radiochemical and ultraviolet detection for determination of low activities of uridine 5'-diphosphate-glucuronosyltransferase.
Kaivosaari S; Salonen JS; Mortensen J; Taskinen J
Anal Biochem; 2001 May; 292(2):178-87. PubMed ID: 11355849
[TBL] [Abstract][Full Text] [Related]
36. Identification and properties of a major plasma metabolite of irinotecan (CPT-11) isolated from the plasma of patients.
Rivory LP; Riou JF; Haaz MC; Sable S; Vuilhorgne M; Commerçon A; Pond SM; Robert J
Cancer Res; 1996 Aug; 56(16):3689-94. PubMed ID: 8706009
[TBL] [Abstract][Full Text] [Related]
37. Liquid chromatographic-tandem mass spectrometric assay for the simultaneous quantification of Camptosar and its metabolite SN-38 in mouse plasma and tissues.
Bardin S; Guo W; Johnson JL; Khan S; Ahmad A; Duggan JX; Ayoub J; Ahmad I
J Chromatogr A; 2005 May; 1073(1-2):249-55. PubMed ID: 15909526
[TBL] [Abstract][Full Text] [Related]
38. High-performance liquid chromatographic analysis of the anticancer drug irinotecan (CPT-11) and its active metabolite SN-38 in human plasma.
Schoemaker NE; Rosing H; Jansen S; Schellens JH; Beijnen JH
Ther Drug Monit; 2003 Feb; 25(1):120-4. PubMed ID: 12548157
[TBL] [Abstract][Full Text] [Related]
39. High-performance liquid chromatographic assay for N-glucuronidation of nicotine and cotinine in human liver microsomes.
Nakajima M; Kwon JT; Tanaka E; Yokoi T
Anal Biochem; 2002 Mar; 302(1):131-5. PubMed ID: 11846386
[TBL] [Abstract][Full Text] [Related]
40. A simple HPLC method with fluorescence detection for simultaneous determination of 10-methoxycamptothecin and its metabolite 10-hydroxycamptothecin in rat liver tissue.
Liu Y; Shao C; Fan B; Li S; Wang Y; Zheng J
Drug Res (Stuttg); 2015 Mar; 65(3):147-52. PubMed ID: 24782285
[TBL] [Abstract][Full Text] [Related]
[Previous] [Next] [New Search]