382 related articles for article (PubMed ID: 11513577)
1. Subsite specificity of memapsin 2 (beta-secretase): implications for inhibitor design.
Turner RT; Koelsch G; Hong L; Castanheira P; Ermolieff J; Ghosh AK; Tang J
Biochemistry; 2001 Aug; 40(34):10001-6. PubMed ID: 11513577
[TBL] [Abstract][Full Text] [Related]
2. Crystal structure of memapsin 2 (beta-secretase) in complex with an inhibitor OM00-3.
Hong L; Turner RT; Koelsch G; Shin D; Ghosh AK; Tang J
Biochemistry; 2002 Sep; 41(36):10963-7. PubMed ID: 12206667
[TBL] [Abstract][Full Text] [Related]
3. Specificity of memapsin 1 and its implications on the design of memapsin 2 (beta-secretase) inhibitor selectivity.
Turner RT; Loy JA; Nguyen C; Devasamudram T; Ghosh AK; Koelsch G; Tang J
Biochemistry; 2002 Jul; 41(27):8742-6. PubMed ID: 12093293
[TBL] [Abstract][Full Text] [Related]
4. Predicting memapsin 2 (β-secretase) hydrolytic activity.
Li X; Bo H; Zhang XC; Hartsuck JA; Tang J
Protein Sci; 2010 Nov; 19(11):2175-85. PubMed ID: 20853423
[TBL] [Abstract][Full Text] [Related]
5. Proteolytic activation of recombinant pro-memapsin 2 (pro-beta-secretase) studied with new fluorogenic substrates.
Ermolieff J; Loy JA; Koelsch G; Tang J
Biochemistry; 2000 Oct; 39(40):12450-6. PubMed ID: 11015226
[TBL] [Abstract][Full Text] [Related]
6. Structural locations and functional roles of new subsites S5, S6, and S7 in memapsin 2 (beta-secretase).
Turner RT; Hong L; Koelsch G; Ghosh AK; Tang J
Biochemistry; 2005 Jan; 44(1):105-12. PubMed ID: 15628850
[TBL] [Abstract][Full Text] [Related]
7. Human aspartic protease memapsin 2 cleaves the beta-secretase site of beta-amyloid precursor protein.
Lin X; Koelsch G; Wu S; Downs D; Dashti A; Tang J
Proc Natl Acad Sci U S A; 2000 Feb; 97(4):1456-60. PubMed ID: 10677483
[TBL] [Abstract][Full Text] [Related]
8. Memapsin 2 (beta-secretase) as a therapeutic target.
Hong L; Turner RT; Koelsch G; Ghosh AK; Tang J
Biochem Soc Trans; 2002 Aug; 30(4):530-4. PubMed ID: 12196130
[TBL] [Abstract][Full Text] [Related]
9. Structure-based design: potent inhibitors of human brain memapsin 2 (beta-secretase).
Ghosh AK; Bilcer G; Harwood C; Kawahama R; Shin D; Hussain KA; Hong L; Loy JA; Nguyen C; Koelsch G; Ermolieff J; Tang J
J Med Chem; 2001 Aug; 44(18):2865-8. PubMed ID: 11520194
[TBL] [Abstract][Full Text] [Related]
10. Structure of the protease domain of memapsin 2 (beta-secretase) complexed with inhibitor.
Hong L; Koelsch G; Lin X; Wu S; Terzyan S; Ghosh AK; Zhang XC; Tang J
Science; 2000 Oct; 290(5489):150-3. PubMed ID: 11021803
[TBL] [Abstract][Full Text] [Related]
11. Beta-secretase as a therapeutic target for inhibitor drugs.
Ghosh AK; Hong L; Tang J
Curr Med Chem; 2002 Jun; 9(11):1135-44. PubMed ID: 12052177
[TBL] [Abstract][Full Text] [Related]
12. Primary structure of murine major histocompatibility complex alloantigens: amino acid sequence of the amino-terminal one hundred and seventy-three residues of the H-2Kb glycoprotein.
Uehara H; Ewenstein BM; Martinko JM; Nathenson SG; Coligan JE; Kindt TJ
Biochemistry; 1980 Jan; 19(2):306-15. PubMed ID: 6986168
[TBL] [Abstract][Full Text] [Related]
13. Structure-activity relationship of memapsin 2: implications on physiological functions and Alzheimer's disease.
Li X; Hong L; Coughlan K; Wang L; Cao L; Tang J
Acta Biochim Biophys Sin (Shanghai); 2013 Aug; 45(8):613-21. PubMed ID: 23676825
[TBL] [Abstract][Full Text] [Related]
14. Structural features of human memapsin 2 (beta-secretase) and their biological and pathological implications.
Hong L; He X; Huang X; Chang W; Tang J
Acta Biochim Biophys Sin (Shanghai); 2004 Dec; 36(12):787-92. PubMed ID: 15592644
[TBL] [Abstract][Full Text] [Related]
15. Memapsin 2 (beta-secretase) cytosolic domain binds to the VHS domains of GGA1 and GGA2: implications on the endocytosis mechanism of memapsin 2.
He X; Chang WP; Koelsch G; Tang J
FEBS Lett; 2002 Jul; 524(1-3):183-7. PubMed ID: 12135764
[TBL] [Abstract][Full Text] [Related]
16. Memapsin 2, a drug target for Alzheimer's disease.
Koelsch G; Turner RT; Hong L; Ghosh AK; Tang J
Biochem Soc Symp; 2003; (70):213-20. PubMed ID: 14587294
[TBL] [Abstract][Full Text] [Related]
17. Biochemical and structural characterization of the interaction of memapsin 2 (beta-secretase) cytosolic domain with the VHS domain of GGA proteins.
He X; Zhu G; Koelsch G; Rodgers KK; Zhang XC; Tang J
Biochemistry; 2003 Oct; 42(42):12174-80. PubMed ID: 14567678
[TBL] [Abstract][Full Text] [Related]
18. Modeling of substrate specificity of the Alzheimer's disease amyloid precursor protein beta-secretase.
Sauder JM; Arthur JW; Dunbrack RL
J Mol Biol; 2000 Jul; 300(2):241-8. PubMed ID: 10873463
[TBL] [Abstract][Full Text] [Related]
19. Amino acid sequence of bovine brain derived class 1 heparin-binding growth factor.
Strydom DJ; Harper JW; Lobb RR
Biochemistry; 1986 Mar; 25(5):945-51. PubMed ID: 2421762
[TBL] [Abstract][Full Text] [Related]
20. Study of memapsin 2 (beta-secretase) and strategy of inhibitor design.
Tang J; Ghosh AK; Hong L; Koelsch G; Turner RT; Chang W
J Mol Neurosci; 2003; 20(3):299-304. PubMed ID: 14501012
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
