BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

163 related articles for article (PubMed ID: 11513582)

  • 1. Crystal structure of thrombin-ecotin reveals conformational changes and extended interactions.
    Wang SX; Esmon CT; Fletterick RJ
    Biochemistry; 2001 Aug; 40(34):10038-46. PubMed ID: 11513582
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Compromise and accommodation in ecotin, a dimeric macromolecular inhibitor of serine proteases.
    Gillmor SA; Takeuchi T; Yang SQ; Craik CS; Fletterick RJ
    J Mol Biol; 2000 Jun; 299(4):993-1003. PubMed ID: 10843853
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The extended interactions and Gla domain of blood coagulation factor Xa.
    Wang SX; Hur E; Sousa CA; Brinen L; Slivka EJ; Fletterick RJ
    Biochemistry; 2003 Jul; 42(26):7959-66. PubMed ID: 12834348
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Structural features of a snake venom thrombin-like enzyme: thrombin and trypsin on a single catalytic platform?
    Castro HC; Silva DM; Craik C; Zingali RB
    Biochim Biophys Acta; 2001 Jun; 1547(2):183-95. PubMed ID: 11410274
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Ecotin: a serine protease inhibitor with two distinct and interacting binding sites.
    Yang SQ; Wang CI; Gillmor SA; Fletterick RJ; Craik CS
    J Mol Biol; 1998 Jun; 279(4):945-57. PubMed ID: 9642073
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Ecotin: lessons on survival in a protease-filled world.
    McGrath ME; Gillmor SA; Fletterick RJ
    Protein Sci; 1995 Feb; 4(2):141-8. PubMed ID: 7757004
    [TBL] [Abstract][Full Text] [Related]  

  • 7. The role of ecotin dimerization in protease inhibition.
    Eggers CT; Wang SX; Fletterick RJ; Craik CS
    J Mol Biol; 2001 May; 308(5):975-91. PubMed ID: 11352586
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Ecotin modulates thrombin activity through exosite-2 interactions.
    Castro HC; Monteiro RQ; Assafim M; Loureiro NI; Craik C; Zingali RB
    Int J Biochem Cell Biol; 2006; 38(11):1893-900. PubMed ID: 16843700
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Crystal structure of an ecotin-collagenase complex suggests a model for recognition and cleavage of the collagen triple helix.
    Perona JJ; Tsu CA; Craik CS; Fletterick RJ
    Biochemistry; 1997 May; 36(18):5381-92. PubMed ID: 9154920
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Engineering bidentate macromolecular inhibitors for trypsin and urokinase-type plasminogen activator.
    Yang SQ; Craik CS
    J Mol Biol; 1998 Jun; 279(4):1001-11. PubMed ID: 9642077
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Crystal structure analyses of uncomplexed ecotin in two crystal forms: implications for its function and stability.
    Shin DH; Song HK; Seong IS; Lee CS; Chung CH; Suh SW
    Protein Sci; 1996 Nov; 5(11):2236-47. PubMed ID: 8931142
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Isolation of a high affinity inhibitor of urokinase-type plasminogen activator by phage display of ecotin.
    Wang CI; Yang Q; Craik CS
    J Biol Chem; 1995 May; 270(20):12250-6. PubMed ID: 7744876
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The P1 reactive site methionine residue of ecotin is not crucial for its specificity on target proteases. A potent inhibitor of pancreatic serine proteases from Escherichia coli.
    Seong IS; Lee HR; Seol JH; Park SK; Lee CS; Suh SW; Hong YM; Kang MS; Ha DB; Chung CH
    J Biol Chem; 1994 Aug; 269(34):21915-8. PubMed ID: 8063835
    [TBL] [Abstract][Full Text] [Related]  

  • 14. The periplasmic serine protease inhibitor ecotin protects bacteria against neutrophil elastase.
    Eggers CT; Murray IA; Delmar VA; Day AG; Craik CS
    Biochem J; 2004 Apr; 379(Pt 1):107-18. PubMed ID: 14705961
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Alteration of the specificity of ecotin, an E. coli serine proteinase inhibitor, by site directed mutagenesis.
    Pál G; Sprengel G; Patthy A; Gráf L
    FEBS Lett; 1994 Mar; 342(1):57-60. PubMed ID: 8143850
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Stable monomeric form of an originally dimeric serine proteinase inhibitor, ecotin, was constructed via site directed mutagenesis.
    Pál G; Szilágyi L; Gráf L
    FEBS Lett; 1996 May; 385(3):165-70. PubMed ID: 8647243
    [TBL] [Abstract][Full Text] [Related]  

  • 17. The refined 1.9-A X-ray crystal structure of D-Phe-Pro-Arg chloromethylketone-inhibited human alpha-thrombin: structure analysis, overall structure, electrostatic properties, detailed active-site geometry, and structure-function relationships.
    Bode W; Turk D; Karshikov A
    Protein Sci; 1992 Apr; 1(4):426-71. PubMed ID: 1304349
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Ecotin is a potent anticoagulant and reversible tight-binding inhibitor of factor Xa.
    Seymour JL; Lindquist RN; Dennis MS; Moffat B; Yansura D; Reilly D; Wessinger ME; Lazarus RA
    Biochemistry; 1994 Apr; 33(13):3949-58. PubMed ID: 8142399
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Profiling the structural determinants for the selectivity of representative factor-Xa and thrombin inhibitors using combined ligand-based and structure-based approaches.
    Bhunia SS; Roy KK; Saxena AK
    J Chem Inf Model; 2011 Aug; 51(8):1966-85. PubMed ID: 21761917
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Engineering ecotin for identifying proteins with a trypsin fold.
    Sathler PC; Craik CS; Takeuchi T; Zingali RB; Castro HC
    Appl Biochem Biotechnol; 2010 Apr; 160(8):2355-65. PubMed ID: 19728173
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 9.