BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

235 related articles for article (PubMed ID: 11513587)

  • 1. DNA aptamers selected against the HIV-1 RNase H display in vitro antiviral activity.
    Andreola ML; Pileur F; Calmels C; Ventura M; Tarrago-Litvak L; Toulmé JJ; Litvak S
    Biochemistry; 2001 Aug; 40(34):10087-94. PubMed ID: 11513587
    [TBL] [Abstract][Full Text] [Related]  

  • 2. DNA aptamers derived from HIV-1 RNase H inhibitors are strong anti-integrase agents.
    de Soultrait VR; Lozach PY; Altmeyer R; Tarrago-Litvak L; Litvak S; Andréola ML
    J Mol Biol; 2002 Nov; 324(2):195-203. PubMed ID: 12441099
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Combinatorial selection, inhibition, and antiviral activity of DNA thioaptamers targeting the RNase H domain of HIV-1 reverse transcriptase.
    Somasunderam A; Ferguson MR; Rojo DR; Thiviyanathan V; Li X; O'Brien WA; Gorenstein DG
    Biochemistry; 2005 Aug; 44(30):10388-95. PubMed ID: 16042416
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Design, synthesis and antiviral evaluation of novel heteroarylcarbothioamide derivatives as dual inhibitors of HIV-1 reverse transcriptase-associated RNase H and RDDP functions.
    Corona A; Onnis V; Deplano A; Bianco G; Demurtas M; Distinto S; Cheng YC; Alcaro S; Esposito F; Tramontano E
    Pathog Dis; 2017 Aug; 75(6):. PubMed ID: 28859311
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Towards the selection of phosphorothioate aptamers optimizing in vitro selection steps with phosphorothioate nucleotides.
    Andreola ML; Calmels C; Michel J; Toulmé JJ; Litvak S
    Eur J Biochem; 2000 Aug; 267(16):5032-40. PubMed ID: 10931185
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Potent inhibition of human immunodeficiency virus type 1 replication by template analog reverse transcriptase inhibitors derived by SELEX (systematic evolution of ligands by exponential enrichment).
    Joshi P; Prasad VR
    J Virol; 2002 Jul; 76(13):6545-57. PubMed ID: 12050367
    [TBL] [Abstract][Full Text] [Related]  

  • 7. HIV-1 integrase and RNase H activities as therapeutic targets.
    Andréola ML; De Soultrait VR; Fournier M; Parissi V; Desjobert C; Litvak S
    Expert Opin Ther Targets; 2002 Aug; 6(4):433-46. PubMed ID: 12223059
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Inhibition of the DNA polymerase and RNase H activities of HIV-1 reverse transcriptase and HIV-1 replication by Brasenia schreberi (Junsai) and Petasites japonicus (Fuki) components.
    Hisayoshi T; Shinomura M; Yokokawa K; Kuze I; Konishi A; Kawaji K; Kodama EN; Hata K; Takahashi S; Nirasawa S; Sakuda S; Yasukawa K
    J Nat Med; 2015 Jul; 69(3):432-40. PubMed ID: 25663480
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Inhibition of the ribonuclease H and DNA polymerase activities of HIV-1 reverse transcriptase by N-(4-tert-butylbenzoyl)-2-hydroxy-1-naphthaldehyde hydrazone.
    Borkow G; Fletcher RS; Barnard J; Arion D; Motakis D; Dmitrienko GI; Parniak MA
    Biochemistry; 1997 Mar; 36(11):3179-85. PubMed ID: 9115994
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Targeting HIV-1 integrase with aptamers selected against the purified RNase H domain of HIV-1 RT.
    Métifiot M; Leon O; Tarrago-Litvak L; Litvak S; Andréola ML
    Biochimie; 2005; 87(9-10):911-9. PubMed ID: 16164998
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Drug targeting of HIV-1 RNA.DNA hybrid structures: thermodynamics of recognition and impact on reverse transcriptase-mediated ribonuclease H activity and viral replication.
    Li TK; Barbieri CM; Lin HC; Rabson AB; Yang G; Fan Y; Gaffney BL; Jones RA; Pilch DS
    Biochemistry; 2004 Aug; 43(30):9732-42. PubMed ID: 15274628
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Closely related antiretroviral agents as inhibitors of two HIV-1 enzymes, ribonuclease H and integrase: "killing two birds with one stone".
    Andréola ML
    Curr Pharm Des; 2004; 10(30):3713-23. PubMed ID: 15579066
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis, biological evaluation and molecular modeling of 2-Hydroxyisoquinoline-1,3-dione analogues as inhibitors of HIV reverse transcriptase associated ribonuclease H and polymerase.
    Tang J; Vernekar SKV; Chen YL; Miller L; Huber AD; Myshakina N; Sarafianos SG; Parniak MA; Wang Z
    Eur J Med Chem; 2017 Jun; 133():85-96. PubMed ID: 28384548
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Developing and Evaluating Inhibitors against the RNase H Active Site of HIV-1 Reverse Transcriptase.
    Boyer PL; Smith SJ; Zhao XZ; Das K; Gruber K; Arnold E; Burke TR; Hughes SH
    J Virol; 2018 Jul; 92(13):. PubMed ID: 29643235
    [TBL] [Abstract][Full Text] [Related]  

  • 15. The ribonuclease H activity of the reverse transcriptases of human immunodeficiency viruses type 1 and type 2 is affected by the thumb subdomain of the small protein subunits.
    Sevilya Z; Loya S; Hughes SH; Hizi A
    J Mol Biol; 2001 Aug; 311(5):957-71. PubMed ID: 11531332
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Multi-target activity of Hemidesmus indicus decoction against innovative HIV-1 drug targets and characterization of Lupeol mode of action.
    Esposito F; Mandrone M; Del Vecchio C; Carli I; Distinto S; Corona A; Lianza M; Piano D; Tacchini M; Maccioni E; Cottiglia F; Saccon E; Poli F; Parolin C; Tramontano E
    Pathog Dis; 2017 Aug; 75(6):. PubMed ID: 28637198
    [TBL] [Abstract][Full Text] [Related]  

  • 17. 6-[1-(4-Fluorophenyl)methyl-1H-pyrrol-2-yl)]-2,4-dioxo-5-hexenoic acid ethyl ester a novel diketo acid derivative which selectively inhibits the HIV-1 viral replication in cell culture and the ribonuclease H activity in vitro.
    Tramontano E; Esposito F; Badas R; Di Santo R; Costi R; La Colla P
    Antiviral Res; 2005 Feb; 65(2):117-24. PubMed ID: 15708638
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Similarities and differences in the RNase H activities of human immunodeficiency virus type 1 reverse transcriptase and Moloney murine leukemia virus reverse transcriptase.
    Gao HQ; Sarafianos SG; Arnold E; Hughes SH
    J Mol Biol; 1999 Dec; 294(5):1097-113. PubMed ID: 10600369
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Ribonuclease H/DNA Polymerase HIV-1 Reverse Transcriptase Dual Inhibitor: Mechanistic Studies on the Allosteric Mode of Action of Isatin-Based Compound RMNC6.
    Corona A; Meleddu R; Esposito F; Distinto S; Bianco G; Masaoka T; Maccioni E; Menéndez-Arias L; Alcaro S; Le Grice SF; Tramontano E
    PLoS One; 2016; 11(1):e0147225. PubMed ID: 26800261
    [TBL] [Abstract][Full Text] [Related]  

  • 20. High-affinity ssDNA inhibitors of the reverse transcriptase of type 1 human immunodeficiency virus.
    Schneider DJ; Feigon J; Hostomsky Z; Gold L
    Biochemistry; 1995 Jul; 34(29):9599-610. PubMed ID: 7542922
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 12.