291 related articles for article (PubMed ID: 11520894)
1. Intraneuronal N-acetylaspartate supplies acetyl groups for myelin lipid synthesis: evidence for myelin-associated aspartoacylase.
Chakraborty G; Mekala P; Yahya D; Wu G; Ledeen RW
J Neurochem; 2001 Aug; 78(4):736-45. PubMed ID: 11520894
[TBL] [Abstract][Full Text] [Related]
2. N-acetylaspartate supports the energetic demands of developmental myelination via oligodendroglial aspartoacylase.
Francis JS; Wojtas I; Markov V; Gray SJ; McCown TJ; Samulski RJ; Bilaniuk LT; Wang DJ; De Vivo DC; Janson CG; Leone P
Neurobiol Dis; 2016 Dec; 96():323-334. PubMed ID: 27717881
[TBL] [Abstract][Full Text] [Related]
3. N-Acetylaspartate Synthase Deficiency Corrects the Myelin Phenotype in a Canavan Disease Mouse Model But Does Not Affect Survival Time.
Maier H; Wang-Eckhardt L; Hartmann D; Gieselmann V; Eckhardt M
J Neurosci; 2015 Oct; 35(43):14501-16. PubMed ID: 26511242
[TBL] [Abstract][Full Text] [Related]
4. Defective N-acetylaspartate catabolism reduces brain acetate levels and myelin lipid synthesis in Canavan's disease.
Madhavarao CN; Arun P; Moffett JR; Szucs S; Surendran S; Matalon R; Garbern J; Hristova D; Johnson A; Jiang W; Namboodiri MA
Proc Natl Acad Sci U S A; 2005 Apr; 102(14):5221-6. PubMed ID: 15784740
[TBL] [Abstract][Full Text] [Related]
5. Bimodal occurrence of aspartoacylase in myelin and cytosol of brain.
Wang J; Matalon R; Bhatia G; Wu G; Li H; Liu T; Lu ZH; Ledeen RW
J Neurochem; 2007 Apr; 101(2):448-57. PubMed ID: 17254025
[TBL] [Abstract][Full Text] [Related]
6. Uncoupling N-acetylaspartate from brain pathology: implications for Canavan disease gene therapy.
von Jonquieres G; Spencer ZHT; Rowlands BD; Klugmann CB; Bongers A; Harasta AE; Parley KE; Cederholm J; Teahan O; Pickford R; Delerue F; Ittner LM; Fröhlich D; McLean CA; Don AS; Schneider M; Housley GD; Rae CD; Klugmann M
Acta Neuropathol; 2018 Jan; 135(1):95-113. PubMed ID: 29116375
[TBL] [Abstract][Full Text] [Related]
7. Aspartoacylase is restricted primarily to myelin synthesizing cells in the CNS: therapeutic implications for Canavan disease.
Kirmani BF; Jacobowitz DM; Kallarakal AT; Namboodiri MA
Brain Res Mol Brain Res; 2002 Nov; 107(2):176-82. PubMed ID: 12487123
[TBL] [Abstract][Full Text] [Related]
8. Myelin lipid abnormalities in the aspartoacylase-deficient tremor rat.
Wang J; Leone P; Wu G; Francis JS; Li H; Jain MR; Serikawa T; Ledeen RW
Neurochem Res; 2009 Jan; 34(1):138-48. PubMed ID: 18478328
[TBL] [Abstract][Full Text] [Related]
9. Canavan disease. Analysis of the nature of the metabolic lesions responsible for development of the observed clinical symptoms.
Baslow MH; Resnik TR
J Mol Neurosci; 1997 Oct; 9(2):109-25. PubMed ID: 9407392
[TBL] [Abstract][Full Text] [Related]
10. NAAG synthetase deficiency has only low influence on pathogenesis in a Canavan disease mouse model.
Becker I; Wang-Eckhardt L; Eckhardt M
J Inherit Metab Dis; 2024 Mar; 47(2):230-243. PubMed ID: 38011891
[TBL] [Abstract][Full Text] [Related]
11. Metabolic acetate therapy improves phenotype in the tremor rat model of Canavan disease.
Arun P; Madhavarao CN; Moffett JR; Hamilton K; Grunberg NE; Ariyannur PS; Gahl WA; Anikster Y; Mog S; Hallows WC; Denu JM; Namboodiri AM
J Inherit Metab Dis; 2010 Jun; 33(3):195-210. PubMed ID: 20464498
[TBL] [Abstract][Full Text] [Related]
12. Restoration of aspartoacylase activity in CNS neurons does not ameliorate motor deficits and demyelination in a model of Canavan disease.
Klugmann M; Leichtlein CB; Symes CW; Serikawa T; Young D; During MJ
Mol Ther; 2005 May; 11(5):745-53. PubMed ID: 15851013
[TBL] [Abstract][Full Text] [Related]
13. Nur7 is a nonsense mutation in the mouse aspartoacylase gene that causes spongy degeneration of the CNS.
Traka M; Wollmann RL; Cerda SR; Dugas J; Barres BA; Popko B
J Neurosci; 2008 Nov; 28(45):11537-49. PubMed ID: 18987190
[TBL] [Abstract][Full Text] [Related]
14. N-Acetylaspartate in the CNS: from neurodiagnostics to neurobiology.
Moffett JR; Ross B; Arun P; Madhavarao CN; Namboodiri AM
Prog Neurobiol; 2007 Feb; 81(2):89-131. PubMed ID: 17275978
[TBL] [Abstract][Full Text] [Related]
15. Are astrocytes the missing link between lack of brain aspartoacylase activity and the spongiform leukodystrophy in Canavan disease?
Baslow MH; Guilfoyle DN
Neurochem Res; 2009 Sep; 34(9):1523-34. PubMed ID: 19319678
[TBL] [Abstract][Full Text] [Related]
16. Suppressing N-Acetyl-l-Aspartate Synthesis Prevents Loss of Neurons in a Murine Model of Canavan Leukodystrophy.
Sohn J; Bannerman P; Guo F; Burns T; Miers L; Croteau C; Singhal NK; McDonough JA; Pleasure D
J Neurosci; 2017 Jan; 37(2):413-421. PubMed ID: 28077719
[TBL] [Abstract][Full Text] [Related]
17. Aspartoacylase supports oxidative energy metabolism during myelination.
Francis JS; Strande L; Markov V; Leone P
J Cereb Blood Flow Metab; 2012 Sep; 32(9):1725-36. PubMed ID: 22617649
[TBL] [Abstract][Full Text] [Related]
18. The neuronal metabolite NAA regulates histone H3 methylation in oligodendrocytes and myelin lipid composition.
Singhal NK; Huang H; Li S; Clements R; Gadd J; Daniels A; Kooijman EE; Bannerman P; Burns T; Guo F; Pleasure D; Freeman E; Shriver L; McDonough J
Exp Brain Res; 2017 Jan; 235(1):279-292. PubMed ID: 27709268
[TBL] [Abstract][Full Text] [Related]
19. Downregulation of aspartoacylase during the progression of myelin breakdown in the dmy mutant rat with mitochondrial magnesium channel MRS2 defect.
Kuwamura M; Tanimura S; Hasegawa Y; Hoshiai R; Moriyama Y; Tanaka M; Takenaka S; Nagayoshi H; Izawa T; Yamate J; Kuramoto T; Serikawa T
Brain Res; 2019 Sep; 1718():169-175. PubMed ID: 31100216
[TBL] [Abstract][Full Text] [Related]
20. Expression of aspartoacylase activity in cultured rat macroglial cells is limited to oligodendrocytes.
Baslow MH; Suckow RF; Sapirstein V; Hungund BL
J Mol Neurosci; 1999; 13(1-2):47-53. PubMed ID: 10691291
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
