BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

158 related articles for article (PubMed ID: 11521173)

  • 1. NF449: a subnanomolar potency antagonist at recombinant rat P2X1 receptors.
    Braun K; Rettinger J; Ganso M; Kassack M; Hildebrandt C; Ullmann H; Nickel P; Schmalzing G; Lambrecht G
    Naunyn Schmiedebergs Arch Pharmacol; 2001 Sep; 364(3):285-90. PubMed ID: 11521173
    [TBL] [Abstract][Full Text] [Related]  

  • 2. NF279: a novel potent and selective antagonist of P2X receptor-mediated responses.
    Damer S; Niebel B; Czeche S; Nickel P; Ardanuy U; Schmalzing G; Rettinger J; Mutschler E; Lambrecht G
    Eur J Pharmacol; 1998 May; 350(1):R5-6. PubMed ID: 9683026
    [TBL] [Abstract][Full Text] [Related]  

  • 3. The suramin analog 4,4',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis (carbonylimino)))tetra-kis-benzenesulfonic acid (NF110) potently blocks P2X3 receptors: subtype selectivity is determined by location of sulfonic acid groups.
    Hausmann R; Rettinger J; Gerevich Z; Meis S; Kassack MU; Illes P; Lambrecht G; Schmalzing G
    Mol Pharmacol; 2006 Jun; 69(6):2058-67. PubMed ID: 16551782
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Inhibition of platelet functions and thrombosis through selective or nonselective inhibition of the platelet P2 receptors with increasing doses of NF449 [4,4',4'',4'''-(carbonylbis(imino-5,1,3-benzenetriylbis-(carbonylimino)))tetrakis-benzene-1,3-disulfonic acid octasodium salt].
    Hechler B; Magnenat S; Zighetti ML; Kassack MU; Ullmann H; Cazenave JP; Evans R; Cattaneo M; Gachet C
    J Pharmacol Exp Ther; 2005 Jul; 314(1):232-43. PubMed ID: 15792995
    [TBL] [Abstract][Full Text] [Related]  

  • 5. The novel heteromeric bivalent ligand SB9 potently antagonizes P2Y(1) receptor-mediated responses.
    Lambrecht G; Ganso M; Bäumert HG; Spatz-Kümbel G; Hildebrandt C; Braun K; Mutschler E
    J Auton Nerv Syst; 2000 Jul; 81(1-3):171-7. PubMed ID: 10869717
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Identification of atropine- and P2X1 receptor antagonist-resistant, neurogenic contractions of the urinary bladder.
    Kennedy C; Tasker PN; Gallacher G; Westfall TD
    J Neurosci; 2007 Jan; 27(4):845-51. PubMed ID: 17251425
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Profiling at recombinant homomeric and heteromeric rat P2X receptors identifies the suramin analogue NF449 as a highly potent P2X1 receptor antagonist.
    Rettinger J; Braun K; Hochmann H; Kassack MU; Ullmann H; Nickel P; Schmalzing G; Lambrecht G
    Neuropharmacology; 2005 Mar; 48(3):461-8. PubMed ID: 15721178
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Concomitant blockade of P2X-receptors and ecto-nucleotidases by P2-receptor antagonists: functional consequences in rat vas deferens.
    Bültmann R; Trendelenburg M; Tuluc F; Wittenburg H; Starke K
    Naunyn Schmiedebergs Arch Pharmacol; 1999 Apr; 359(4):339-44. PubMed ID: 10344533
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Structure-activity relationships of analogues of NF449 confirm NF449 as the most potent and selective known P2X1 receptor antagonist.
    Kassack MU; Braun K; Ganso M; Ullmann H; Nickel P; Böing B; Müller G; Lambrecht G
    Eur J Med Chem; 2004 Apr; 39(4):345-57. PubMed ID: 15072843
    [TBL] [Abstract][Full Text] [Related]  

  • 10. NF449, a novel picomolar potency antagonist at human P2X1 receptors.
    Hülsmann M; Nickel P; Kassack M; Schmalzing G; Lambrecht G; Markwardt F
    Eur J Pharmacol; 2003 May; 470(1-2):1-7. PubMed ID: 12787824
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Differential effects of suramin on P2-purinoceptors mediating contraction of the guinea-pig vas deferens and urinary bladder.
    Bailey SJ; Hourani SM
    Br J Pharmacol; 1994 May; 112(1):219-25. PubMed ID: 8032645
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Design and pharmacology of selective P2-purinoceptor antagonists.
    Lambrecht G
    J Auton Pharmacol; 1996 Dec; 16(6):341-4. PubMed ID: 9131412
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The novel suramin analogue NF864 selectively blocks P2X1 receptors in human platelets with potency in the low nanomolar range.
    Horner S; Menke K; Hildebrandt C; Kassack MU; Nickel P; Ullmann H; Mahaut-Smith MP; Lambrecht G
    Naunyn Schmiedebergs Arch Pharmacol; 2005 Jul; 372(1):1-13. PubMed ID: 16158305
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ectodomain lysines and suramin block of P2X1 receptors.
    Sim JA; Broomhead HE; North RA
    J Biol Chem; 2008 Oct; 283(44):29841-6. PubMed ID: 18765669
    [TBL] [Abstract][Full Text] [Related]  

  • 15. P2-purinoceptor antagonists: III. Blockade of P2-purinoceptor subtypes and ecto-nucleotidases by compounds related to suramin.
    Bültmann R; Wittenburg H; Pause B; Kurz G; Nickel P; Starke K
    Naunyn Schmiedebergs Arch Pharmacol; 1996 Oct; 354(4):498-504. PubMed ID: 8897454
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Use of chimeras, point mutants, and molecular modeling to map the antagonist-binding site of 4,4',4″,4‴-(carbonylbis-(imino-5,1,3-benzenetriylbis(carbonylimino)))tetrakisbenzene-1,3-disulfonic acid (NF449) at P2X1 receptors for ATP.
    Farmer LK; Schmid R; Evans RJ
    J Biol Chem; 2015 Jan; 290(3):1559-69. PubMed ID: 25425641
    [TBL] [Abstract][Full Text] [Related]  

  • 17. P2-purinoceptor antagonists: I. Blockade of P2-purinoceptor subtypes and ecto-nucleotidases by small aromatic isothiocyanato-sulphonates.
    Bültmann R; Pause B; Wittenburg H; Kurz G; Starke K
    Naunyn Schmiedebergs Arch Pharmacol; 1996 Oct; 354(4):481-90. PubMed ID: 8897452
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Molecular basis of selective antagonism of the P2X1 receptor for ATP by NF449 and suramin: contribution of basic amino acids in the cysteine-rich loop.
    El-Ajouz S; Ray D; Allsopp RC; Evans RJ
    Br J Pharmacol; 2012 Jan; 165(2):390-400. PubMed ID: 21671897
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Antagonistic properties of the suramin analogue NF023 at heterologously expressed P2X receptors.
    Soto F; Lambrecht G; Nickel P; Stühmer W; Busch AE
    Neuropharmacology; 1999 Jan; 38(1):141-9. PubMed ID: 10193905
    [TBL] [Abstract][Full Text] [Related]  

  • 20. P2-receptor antagonists: IV. Blockade of P2-receptor subtypes and ecto-nucleotidases by compounds related to reactive blue 2.
    Tuluc F; Bültmann R; Glänzel M; Frahm AW; Starke K
    Naunyn Schmiedebergs Arch Pharmacol; 1998 Feb; 357(2):111-20. PubMed ID: 9521483
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.