BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

568 related articles for article (PubMed ID: 11522624)

  • 1. Mutability of p53 hotspot codons to benzo(a)pyrene diol epoxide (BPDE) and the frequency of p53 mutations in nontumorous human lung.
    Hussain SP; Amstad P; Raja K; Sawyer M; Hofseth L; Shields PG; Hewer A; Phillips DH; Ryberg D; Haugen A; Harris CC
    Cancer Res; 2001 Sep; 61(17):6350-5. PubMed ID: 11522624
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Methylated CpG dinucleotides are the preferential targets for G-to-T transversion mutations induced by benzo[a]pyrene diol epoxide in mammalian cells: similarities with the p53 mutation spectrum in smoking-associated lung cancers.
    Yoon JH; Smith LE; Feng Z; Tang M; Lee CS; Pfeifer GP
    Cancer Res; 2001 Oct; 61(19):7110-7. PubMed ID: 11585742
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Comparison of mutations in the p53 and K-ras genes in lung carcinomas from smoking and nonsmoking women.
    Gealy R; Zhang L; Siegfried JM; Luketich JD; Keohavong P
    Cancer Epidemiol Biomarkers Prev; 1999 Apr; 8(4 Pt 1):297-302. PubMed ID: 10207632
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Formation of diastereomeric benzo[a]pyrene diol epoxide-guanine adducts in p53 gene-derived DNA sequences.
    Matter B; Wang G; Jones R; Tretyakova N
    Chem Res Toxicol; 2004 Jun; 17(6):731-41. PubMed ID: 15206894
    [TBL] [Abstract][Full Text] [Related]  

  • 5. p53 mutations in benzo(a)pyrene-exposed human p53 knock-in murine fibroblasts correlate with p53 mutations in human lung tumors.
    Liu Z; Muehlbauer KR; Schmeiser HH; Hergenhahn M; Belharazem D; Hollstein MC
    Cancer Res; 2005 Apr; 65(7):2583-7. PubMed ID: 15805253
    [TBL] [Abstract][Full Text] [Related]  

  • 6. High DNA damage by benzo[a]pyrene 7,8-diol-9,10-epoxide in bronchial epithelial cells from patients with lung cancer: comparison with lung parenchyma.
    Rojas M; Marie B; Vignaud JM; Martinet N; Siat J; Grosdidier G; Cascorbi I; Alexandrov K
    Cancer Lett; 2004 Apr; 207(2):157-63. PubMed ID: 15072824
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Suppressive activities of OGG1 and MYH proteins against G:C to T:A mutations caused by 8-hydroxyguanine but not by benzo[a]pyrene diol epoxide in human cells in vivo.
    Yamane A; Shinmura K; Sunaga N; Saitoh T; Yamaguchi S; Shinmura Y; Yoshimura K; Murakami H; Nojima Y; Kohno T; Yokota J
    Carcinogenesis; 2003 Jun; 24(6):1031-7. PubMed ID: 12807753
    [TBL] [Abstract][Full Text] [Related]  

  • 8. p53 and K-ras mutations in lung cancers from former and never-smoking women.
    Vähäkangas KH; Bennett WP; Castrén K; Welsh JA; Khan MA; Blömeke B; Alavanja MC; Harris CC
    Cancer Res; 2001 Jun; 61(11):4350-6. PubMed ID: 11389059
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Mutagenic potential of benzo[a]pyrene-derived DNA adducts positioned in codon 273 of the human P53 gene.
    Dong H; Bonala RR; Suzuki N; Johnson F; Grollman AP; Shibutani S
    Biochemistry; 2004 Dec; 43(50):15922-8. PubMed ID: 15595848
    [TBL] [Abstract][Full Text] [Related]  

  • 10. p53 mutations and exposure to environmental tobacco smoke in a multicenter study on lung cancer.
    Husgafvel-Pursiainen K; Boffetta P; Kannio A; Nyberg F; Pershagen G; Mukeria A; Constantinescu V; Fortes C; Benhamou S
    Cancer Res; 2000 Jun; 60(11):2906-11. PubMed ID: 10850436
    [TBL] [Abstract][Full Text] [Related]  

  • 11. An improved fluorometric assay for dosimetry of benzo(a)pyrene diol-epoxide-DNA adducts in smokers' lung: comparisons with total bulky adducts and aryl hydrocarbon hydroxylase activity.
    Alexandrov K; Rojas M; Geneste O; Castegnaro M; Camus AM; Petruzzelli S; Giuntini C; Bartsch H
    Cancer Res; 1992 Nov; 52(22):6248-53. PubMed ID: 1423269
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Benzo(a)pyrene diol epoxide-induced chromosomal aberrations and risk of lung cancer.
    Wei Q; Gu J; Cheng L; Bondy ML; Jiang H; Hong WK; Spitz MR
    Cancer Res; 1996 Sep; 56(17):3975-9. PubMed ID: 8752166
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Sensitivity to DNA damage induced by benzo(a)pyrene diol epoxide and risk of lung cancer: a case-control analysis.
    Li D; Firozi PF; Wang LE; Bosken CH; Spitz MR; Hong WK; Wei Q
    Cancer Res; 2001 Feb; 61(4):1445-50. PubMed ID: 11245449
    [TBL] [Abstract][Full Text] [Related]  

  • 14. p53 mutations in lung cancer following radiation therapy for Hodgkin's disease.
    De Benedetti VM; Travis LB; Welsh JA; van Leeuwen FE; Stovall M; Clarke EA; Boice JD; Bennett WP
    Cancer Epidemiol Biomarkers Prev; 1996 Feb; 5(2):93-8. PubMed ID: 8850268
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Hydrocarbon carcinogens evade cellular defense mechanism of G1 arrest in nontransformed and malignant lung cell lines.
    Khan QA; Anderson LM
    Toxicol Appl Pharmacol; 2001 Jun; 173(2):105-13. PubMed ID: 11384212
    [TBL] [Abstract][Full Text] [Related]  

  • 16. A parallel study of in vitro sensitivity to benzo[a]pyrene diol epoxide and bleomycin in lung carcinoma cases and controls.
    Wu X; Gu J; Amos CI; Jiang H; Hong WK; Spitz MR
    Cancer; 1998 Sep; 83(6):1118-27. PubMed ID: 9740076
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Oxy-radical induced mutagenesis of hotspot codons 248 and 249 of the human p53 gene.
    Hussain SP; Aguilar F; Amstad P; Cerutti P
    Oncogene; 1994 Aug; 9(8):2277-81. PubMed ID: 8036011
    [TBL] [Abstract][Full Text] [Related]  

  • 18. TP53 and KRAS mutation load and types in lung cancers in relation to tobacco smoke: distinct patterns in never, former, and current smokers.
    Le Calvez F; Mukeria A; Hunt JD; Kelm O; Hung RJ; Tanière P; Brennan P; Boffetta P; Zaridze DG; Hainaut P
    Cancer Res; 2005 Jun; 65(12):5076-83. PubMed ID: 15958551
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Comparison of p53 mutations induced by PAH o-quinones with those caused by anti-benzo[a]pyrene diol epoxide in vitro: role of reactive oxygen and biological selection.
    Shen YM; Troxel AB; Vedantam S; Penning TM; Field J
    Chem Res Toxicol; 2006 Nov; 19(11):1441-50. PubMed ID: 17112231
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Arsenite enhances the benzo[a]pyrene diol epoxide (BPDE)-induced mutagenesis with no marked effect on repair of BPDE-DNA adducts in human lung cells.
    Chiang HC; Tsou TC
    Toxicol In Vitro; 2009 Aug; 23(5):897-905. PubMed ID: 19470404
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 29.