These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.
3. Sensitive ELISA detection of amyloid-beta protofibrils in biological samples. Englund H; Sehlin D; Johansson AS; Nilsson LN; Gellerfors P; Paulie S; Lannfelt L; Pettersson FE J Neurochem; 2007 Oct; 103(1):334-45. PubMed ID: 17623042 [TBL] [Abstract][Full Text] [Related]
4. The Arctic Alzheimer mutation favors intracellular amyloid-beta production by making amyloid precursor protein less available to alpha-secretase. Sahlin C; Lord A; Magnusson K; Englund H; Almeida CG; Greengard P; Nyberg F; Gouras GK; Lannfelt L; Nilsson LN J Neurochem; 2007 May; 101(3):854-62. PubMed ID: 17448150 [TBL] [Abstract][Full Text] [Related]
5. Physiochemical characterization of the Alzheimer's disease-related peptides A beta 1-42Arctic and A beta 1-42wt. Johansson AS; Berglind-Dehlin F; Karlsson G; Edwards K; Gellerfors P; Lannfelt L FEBS J; 2006 Jun; 273(12):2618-30. PubMed ID: 16817891 [TBL] [Abstract][Full Text] [Related]
6. Evidence that Abeta42 plasma levels in presenilin-1 mutation carriers do not allow for prediction of their clinical phenotype. De Jonghe C; Cras P; Vanderstichele H; Cruts M; Vanderhoeven I; Smouts I; Vanmechelen E; Martin JJ; Hendriks L; Van Broeckhoven C Neurobiol Dis; 1999 Aug; 6(4):280-7. PubMed ID: 10448055 [TBL] [Abstract][Full Text] [Related]
7. A highly insoluble state of Abeta similar to that of Alzheimer's disease brain is found in Arctic APP transgenic mice. Philipson O; Hammarström P; Nilsson KP; Portelius E; Olofsson T; Ingelsson M; Hyman BT; Blennow K; Lannfelt L; Kalimo H; Nilsson LN Neurobiol Aging; 2009 Sep; 30(9):1393-405. PubMed ID: 18192084 [TBL] [Abstract][Full Text] [Related]
8. The Arctic Alzheimer mutation facilitates early intraneuronal Abeta aggregation and senile plaque formation in transgenic mice. Lord A; Kalimo H; Eckman C; Zhang XQ; Lannfelt L; Nilsson LN Neurobiol Aging; 2006 Jan; 27(1):67-77. PubMed ID: 16298242 [TBL] [Abstract][Full Text] [Related]
9. Mutations in amyloid precursor protein and presenilin-1 genes increase the basal oxidative stress in murine neuronal cells and lead to increased sensitivity to oxidative stress mediated by amyloid beta-peptide (1-42), HO and kainic acid: implications for Alzheimer's disease. Mohmmad Abdul H; Sultana R; Keller JN; St Clair DK; Markesbery WR; Butterfield DA J Neurochem; 2006 Mar; 96(5):1322-35. PubMed ID: 16478525 [TBL] [Abstract][Full Text] [Related]
10. Intracellularly generated amyloid-beta peptide counteracts the antiapoptotic function of its precursor protein and primes proapoptotic pathways for activation by other insults in neuroblastoma cells. Esposito L; Gan L; Yu GQ; Essrich C; Mucke L J Neurochem; 2004 Dec; 91(6):1260-74. PubMed ID: 15584903 [TBL] [Abstract][Full Text] [Related]
11. Decreased Abeta secretion by cells expressing familial Alzheimer's disease-linked mutant presenilin 1. Shimojo M; Sahara N; Murayama M; Ichinose H; Takashima A Neurosci Res; 2007 Mar; 57(3):446-53. PubMed ID: 17210196 [TBL] [Abstract][Full Text] [Related]
12. Mutations in APP have independent effects on Abeta and CTFgamma generation. Hecimovic S; Wang J; Dolios G; Martinez M; Wang R; Goate AM Neurobiol Dis; 2004 Nov; 17(2):205-18. PubMed ID: 15474359 [TBL] [Abstract][Full Text] [Related]
13. beta-Secretase, APP and Abeta in Alzheimer's disease. Vassar R Subcell Biochem; 2005; 38():79-103. PubMed ID: 15709474 [TBL] [Abstract][Full Text] [Related]
14. The Arctic amyloid-β precursor protein (AβPP) mutation results in distinct plaques and accumulation of N- and C-truncated Aβ. Philipson O; Lord A; Lalowski M; Soliymani R; Baumann M; Thyberg J; Bogdanovic N; Olofsson T; Tjernberg LO; Ingelsson M; Lannfelt L; Kalimo H; Nilsson LN Neurobiol Aging; 2012 May; 33(5):1010.e1-13. PubMed ID: 22118948 [TBL] [Abstract][Full Text] [Related]
15. Targeted introduction of V642I mutation in amyloid precursor protein gene causes functional abnormality resembling early stage of Alzheimer's disease in aged mice. Kawasumi M; Chiba T; Yamada M; Miyamae-Kaneko M; Matsuoka M; Nakahara J; Tomita T; Iwatsubo T; Kato S; Aiso S; Nishimoto I; Kouyama K Eur J Neurosci; 2004 May; 19(10):2826-38. PubMed ID: 15147316 [TBL] [Abstract][Full Text] [Related]
17. [Advances in molecular biology and clinical study of amyloid precursor protein for Alzheimer's disease]. Xu BG; Wu X Zhongguo Yi Xue Ke Xue Yuan Xue Bao; 2004 Apr; 26(2):201-9. PubMed ID: 15171563 [TBL] [Abstract][Full Text] [Related]