593 related articles for article (PubMed ID: 11529249)
1. A phase I trial of genetically modified Salmonella typhimurium expressing cytosine deaminase (TAPET-CD, VNP20029) administered by intratumoral injection in combination with 5-fluorocytosine for patients with advanced or metastatic cancer. Protocol no: CL-017. Version: April 9, 2001.
Cunningham C; Nemunaitis J
Hum Gene Ther; 2001 Aug; 12(12):1594-6. PubMed ID: 11529249
[TBL] [Abstract][Full Text] [Related]
2. Pilot trial of genetically modified, attenuated Salmonella expressing the E. coli cytosine deaminase gene in refractory cancer patients.
Nemunaitis J; Cunningham C; Senzer N; Kuhn J; Cramm J; Litz C; Cavagnolo R; Cahill A; Clairmont C; Sznol M
Cancer Gene Ther; 2003 Oct; 10(10):737-44. PubMed ID: 14502226
[TBL] [Abstract][Full Text] [Related]
3. Evaluation of the acute and subchronic toxic effects in mice, rats, and monkeys of the genetically engineered and Escherichia coli cytosine deaminase gene-incorporated Salmonella strain, TAPET-CD, being developed as an antitumor agent.
Lee KC; Zheng LM; Margitich D; Almassian B; King I
Int J Toxicol; 2001; 20(4):207-17. PubMed ID: 11563416
[TBL] [Abstract][Full Text] [Related]
4. Tumor-targeted Salmonella expressing cytosine deaminase as an anticancer agent.
King I; Bermudes D; Lin S; Belcourt M; Pike J; Troy K; Le T; Ittensohn M; Mao J; Lang W; Runyan JD; Luo X; Li Z; Zheng LM
Hum Gene Ther; 2002 Jul; 13(10):1225-33. PubMed ID: 12133275
[TBL] [Abstract][Full Text] [Related]
5. Molecular chemotherapy combined with radiation therapy enhances killing of cholangiocarcinoma cells in vitro and in vivo.
Pederson LC; Buchsbaum DJ; Vickers SM; Kancharla SR; Mayo MS; Curiel DT; Stackhouse MA
Cancer Res; 1997 Oct; 57(19):4325-32. PubMed ID: 9331094
[TBL] [Abstract][Full Text] [Related]
6. Intratumoral 5-fluorouracil produced by cytosine deaminase/5-fluorocytosine gene therapy is effective for experimental human glioblastomas.
Miller CR; Williams CR; Buchsbaum DJ; Gillespie GY
Cancer Res; 2002 Feb; 62(3):773-80. PubMed ID: 11830532
[TBL] [Abstract][Full Text] [Related]
7. Optimization of tumor-targeted gene delivery by engineered attenuated Salmonella typhimurium.
Mei S; Theys J; Landuyt W; Anne J; Lambin P
Anticancer Res; 2002; 22(6A):3261-6. PubMed ID: 12530073
[TBL] [Abstract][Full Text] [Related]
8. Combined suicide gene therapy for human colon cancer cells using adenovirus-mediated transfer of escherichia coli cytosine deaminase gene and Escherichia coli uracil phosphoribosyltransferase gene with 5-fluorocytosine.
Koyama F; Sawada H; Hirao T; Fujii H; Hamada H; Nakano H
Cancer Gene Ther; 2000 Jul; 7(7):1015-22. PubMed ID: 10917204
[TBL] [Abstract][Full Text] [Related]
9. Cytosine deaminase-producing human mesenchymal stem cells mediate an antitumor effect in a mouse xenograft model.
You MH; Kim WJ; Shim W; Lee SR; Lee G; Choi S; Kim DY; Kim YM; Kim H; Han SU
J Gastroenterol Hepatol; 2009 Aug; 24(8):1393-400. PubMed ID: 19486256
[TBL] [Abstract][Full Text] [Related]
10. Virally directed cytosine deaminase/5-fluorocytosine gene therapy enhances radiation response in human cancer xenografts.
Hanna NN; Mauceri HJ; Wayne JD; Hallahan DE; Kufe DW; Weichselbaum RR
Cancer Res; 1997 Oct; 57(19):4205-9. PubMed ID: 9331076
[TBL] [Abstract][Full Text] [Related]
11. Enzyme/prodrug gene therapy for human colon cancer cells using adenovirus-mediated transfer of the Escherichia coli cytosine deaminase gene driven by a CAG promoter associated with 5-fluorocytosine administration.
Koyama F; Sawada H; Fujii H; Hirao T; Ueno M; Hamada H; Nakano H
J Exp Clin Cancer Res; 2000 Mar; 19(1):75-80. PubMed ID: 10840940
[TBL] [Abstract][Full Text] [Related]
12. [Anticancer effects of cytosine deaminase gene/5-fluorocytosine therapies to ovarian cancer in vivo].
Yao Y; Peng Z; Wang H; Li Q; Liu S
Zhonghua Fu Chan Ke Za Zhi; 2002 Apr; 37(4):195-7. PubMed ID: 12133407
[TBL] [Abstract][Full Text] [Related]
13. Regional 'pro-drug' gene therapy: intravenous administration of an adenoviral vector expressing the E. coli cytosine deaminase gene and systemic administration of 5-fluorocytosine suppresses growth of hepatic metastasis of colon carcinoma.
Topf N; Worgall S; Hackett NR; Crystal RG
Gene Ther; 1998 Apr; 5(4):507-13. PubMed ID: 9614575
[TBL] [Abstract][Full Text] [Related]
14. Tumor-targeted Salmonella typhimurium overexpressing cytosine deaminase: a novel, tumor-selective therapy.
King I; Itterson M; Bermudes D
Methods Mol Biol; 2009; 542():649-59. PubMed ID: 19565926
[TBL] [Abstract][Full Text] [Related]
15. Intratumoral generation of 5-fluorouracil mediated by an antibody-cytosine deaminase conjugate in combination with 5-fluorocytosine.
Wallace PM; MacMaster JF; Smith VF; Kerr DE; Senter PD; Cosand WL
Cancer Res; 1994 May; 54(10):2719-23. PubMed ID: 8168103
[TBL] [Abstract][Full Text] [Related]
16. Naked DNA injection for liver metastases treatment in rats.
BaquƩ P; Pierrefite-Carle V; Gavelli A; Brossette N; Benchimol D; Bourgeon A; Staccini P; Saint-Paul MC; Rossi B
Hepatology; 2002 May; 35(5):1144-52. PubMed ID: 11981764
[TBL] [Abstract][Full Text] [Related]
17. In vivo antitumor activity of 5-fluorocytosine on human colorectal carcinoma cells genetically modified to express cytosine deaminase.
Huber BE; Austin EA; Good SS; Knick VC; Tibbels S; Richards CA
Cancer Res; 1993 Oct; 53(19):4619-26. PubMed ID: 8402637
[TBL] [Abstract][Full Text] [Related]
18. A Phase I trial of 90Y-anti-carcinoembryonic antigen chimeric T84.66 radioimmunotherapy with 5-fluorouracil in patients with metastatic colorectal cancer.
Wong JY; Shibata S; Williams LE; Kwok CS; Liu A; Chu DZ; Yamauchi DM; Wilczynski S; Ikle DN; Wu AM; Yazaki PJ; Shively JE; Doroshow JH; Raubitschek AA
Clin Cancer Res; 2003 Dec; 9(16 Pt 1):5842-52. PubMed ID: 14676105
[TBL] [Abstract][Full Text] [Related]
19. In vivo efficacy and toxicity of 5-fluorocytosine/cytosine deaminase gene therapy for malignant gliomas mediated by adenovirus.
Ichikawa T; Tamiya T; Adachi Y; Ono Y; Matsumoto K; Furuta T; Yoshida Y; Hamada H; Ohmoto T
Cancer Gene Ther; 2000 Jan; 7(1):74-82. PubMed ID: 10678359
[TBL] [Abstract][Full Text] [Related]
20. 5-Fluorocytosine-induced eradication of murine adenocarcinomas engineered to express the cytosine deaminase suicide gene requires host immune competence and leaves an efficient memory.
Consalvo M; Mullen CA; Modesti A; Musiani P; Allione A; Cavallo F; Giovarelli M; Forni G
J Immunol; 1995 May; 154(10):5302-12. PubMed ID: 7730633
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]