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2. Increased in vivo phosphorylation of ret tyrosine 1062 is a potential pathogenetic mechanism of multiple endocrine neoplasia type 2B. Salvatore D; Melillo RM; Monaco C; Visconti R; Fenzi G; Vecchio G; Fusco A; Santoro M Cancer Res; 2001 Feb; 61(4):1426-31. PubMed ID: 11245446 [TBL] [Abstract][Full Text] [Related]
3. RET-familial medullary thyroid carcinoma mutants Y791F and S891A activate a Src/JAK/STAT3 pathway, independent of glial cell line-derived neurotrophic factor. Plaza Menacho I; Koster R; van der Sloot AM; Quax WJ; Osinga J; van der Sluis T; Hollema H; Burzynski GM; Gimm O; Buys CH; Eggen BJ; Hofstra RM Cancer Res; 2005 Mar; 65(5):1729-37. PubMed ID: 15753368 [TBL] [Abstract][Full Text] [Related]
4. Tyrosine 1062 of RET-MEN2A mediates activation of Akt (protein kinase B) and mitogen-activated protein kinase pathways leading to PC12 cell survival. De Vita G; Melillo RM; Carlomagno F; Visconti R; Castellone MD; Bellacosa A; Billaud M; Fusco A; Tsichlis PN; Santoro M Cancer Res; 2000 Jul; 60(14):3727-31. PubMed ID: 10919641 [TBL] [Abstract][Full Text] [Related]
5. Repair by Src kinase of function-impaired RET with multiple endocrine neoplasia type 2A mutation with substitutions of tyrosines in the COOH-terminal kinase domain for phenylalanine. Kato M; Takeda K; Kawamoto Y; Iwashita T; Akhand AA; Senga T; Yamamoto M; Sobue G; Hamaguchi M; Takahashi M; Nakashima I Cancer Res; 2002 Apr; 62(8):2414-22. PubMed ID: 11956105 [TBL] [Abstract][Full Text] [Related]
6. Identification of tyrosine residues that are essential for transforming activity of the ret proto-oncogene with MEN2A or MEN2B mutation. Iwashita T; Asai N; Murakami H; Matsuyama M; Takahashi M Oncogene; 1996 Feb; 12(3):481-7. PubMed ID: 8637703 [TBL] [Abstract][Full Text] [Related]
7. Activation of signal transducer and activator of transcription 3 by oncogenic RET/PTC (rearranged in transformation/papillary thyroid carcinoma) tyrosine kinase: roles in specific gene regulation and cellular transformation. Hwang JH; Kim DW; Suh JM; Kim H; Song JH; Hwang ES; Park KC; Chung HK; Kim JM; Lee TH; Yu DY; Shong M Mol Endocrinol; 2003 Jun; 17(6):1155-66. PubMed ID: 12637586 [TBL] [Abstract][Full Text] [Related]
8. Cellular effects and antitumor activity of RET inhibitor RPI-1 on MEN2A-associated medullary thyroid carcinoma. Cuccuru G; Lanzi C; Cassinelli G; Pratesi G; Tortoreto M; Petrangolini G; Seregni E; Martinetti A; Laccabue D; Zanchi C; Zunino F J Natl Cancer Inst; 2004 Jul; 96(13):1006-14. PubMed ID: 15240784 [TBL] [Abstract][Full Text] [Related]
9. Activation of RET as a dominant transforming gene by germline mutations of MEN2A and MEN2B. Santoro M; Carlomagno F; Romano A; Bottaro DP; Dathan NA; Grieco M; Fusco A; Vecchio G; Matoskova B; Kraus MH Science; 1995 Jan; 267(5196):381-3. PubMed ID: 7824936 [TBL] [Abstract][Full Text] [Related]
10. Differential effects of leukocyte common antigen-related protein on biochemical and biological activities of RET-MEN2A and RET-MEN2B mutant proteins. Qiao S; Iwashita T; Furukawa T; Yamamoto M; Sobue G; Takahashi M J Biol Chem; 2001 Mar; 276(12):9460-7. PubMed ID: 11121408 [TBL] [Abstract][Full Text] [Related]
11. RET activation by germline MEN2A and MEN2B mutations. Borrello MG; Smith DP; Pasini B; Bongarzone I; Greco A; Lorenzo MJ; Arighi E; Miranda C; Eng C; Alberti L Oncogene; 1995 Dec; 11(11):2419-27. PubMed ID: 8570194 [TBL] [Abstract][Full Text] [Related]
12. Transforming ability of MEN2A-RET requires activation of the phosphatidylinositol 3-kinase/AKT signaling pathway. Segouffin-Cariou C; Billaud M J Biol Chem; 2000 Feb; 275(5):3568-76. PubMed ID: 10652352 [TBL] [Abstract][Full Text] [Related]
13. Regulation of signal transducer and activator of transcription 1 (STAT1) and STAT1-dependent genes by RET/PTC (rearranged in transformation/papillary thyroid carcinoma) oncogenic tyrosine kinases. Hwang ES; Kim DW; Hwang JH; Jung HS; Suh JM; Park YJ; Chung HK; Song JH; Park KC; Park SH; Yun HJ; Kim JM; Shong M Mol Endocrinol; 2004 Nov; 18(11):2672-84. PubMed ID: 15297606 [TBL] [Abstract][Full Text] [Related]
14. Activation of BMK1 via tyrosine 1062 in RET by GDNF and MEN2A mutation. Hayashi Y; Iwashita T; Murakamai H; Kato Y; Kawai K; Kurokawa K; Tohnai I; Ueda M; Takahashi M Biochem Biophys Res Commun; 2001 Mar; 281(3):682-9. PubMed ID: 11237712 [TBL] [Abstract][Full Text] [Related]
15. Glial cell line-derived neurotrophic factor differentially stimulates ret mutants associated with the multiple endocrine neoplasia type 2 syndromes and Hirschsprung's disease. Carlomagno F; Melillo RM; Visconti R; Salvatore G; De Vita G; Lupoli G; Yu Y; Jing S; Vecchio G; Fusco A; Santoro M Endocrinology; 1998 Aug; 139(8):3613-9. PubMed ID: 9681515 [TBL] [Abstract][Full Text] [Related]
16. Role of Dok1 in cell signaling mediated by RET tyrosine kinase. Murakami H; Yamamura Y; Shimono Y; Kawai K; Kurokawa K; Takahashi M J Biol Chem; 2002 Sep; 277(36):32781-90. PubMed ID: 12087092 [TBL] [Abstract][Full Text] [Related]
17. Characterization of Ret-Shc-Grb2 complex induced by GDNF, MEN 2A, and MEN 2B mutations. Ohiwa M; Murakami H; Iwashita T; Asai N; Iwata Y; Imai T; Funahashi H; Takagi H; Takahashi M Biochem Biophys Res Commun; 1997 Aug; 237(3):747-51. PubMed ID: 9299438 [TBL] [Abstract][Full Text] [Related]
18. Role of MEN2A-derived RET in maintenance and proliferation of medullary thyroid carcinoma. Drosten M; Hilken G; Böckmann M; Rödicker F; Mise N; Cranston AN; Dahmen U; Ponder BA; Pützer BM J Natl Cancer Inst; 2004 Aug; 96(16):1231-9. PubMed ID: 15316058 [TBL] [Abstract][Full Text] [Related]
19. Ultraviolet light induces redox reaction-mediated dimerization and superactivation of oncogenic Ret tyrosine kinases. Kato M; Iwashita T; Takeda K; Akhand AA; Liu W; Yoshihara M; Asai N; Suzuki H; Takahashi M; Nakashima I Mol Biol Cell; 2000 Jan; 11(1):93-101. PubMed ID: 10637293 [TBL] [Abstract][Full Text] [Related]
20. Tissue-specific carcinogenesis in transgenic mice expressing the RET proto-oncogene with a multiple endocrine neoplasia type 2A mutation. Kawai K; Iwashita T; Murakami H; Hiraiwa N; Yoshiki A; Kusakabe M; Ono K; Iida K; Nakayama A; Takahashi M Cancer Res; 2000 Sep; 60(18):5254-60. PubMed ID: 11016655 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]