156 related articles for article (PubMed ID: 11557032)
1. Antisense inhibition of Chk2/hCds1 expression attenuates DNA damage-induced S and G2 checkpoints and enhances apoptotic activity in HEK-293 cells.
Yu Q; Rose JH; Zhang H; Pommier Y
FEBS Lett; 2001 Sep; 505(1):7-12. PubMed ID: 11557032
[TBL] [Abstract][Full Text] [Related]
2. Role of human Cds1 (Chk2) kinase in DNA damage checkpoint and its regulation by p53.
Tominaga K; Morisaki H; Kaneko Y; Fujimoto A; Tanaka T; Ohtsubo M; Hirai M; Okayama H; Ikeda K; Nakanishi M
J Biol Chem; 1999 Oct; 274(44):31463-7. PubMed ID: 10531348
[TBL] [Abstract][Full Text] [Related]
3. Chk2/hCds1 functions as a DNA damage checkpoint in G(1) by stabilizing p53.
Chehab NH; Malikzay A; Appel M; Halazonetis TD
Genes Dev; 2000 Feb; 14(3):278-88. PubMed ID: 10673500
[TBL] [Abstract][Full Text] [Related]
4. Chk2 is required for optimal mitotic delay in response to irradiation-induced DNA damage incurred in G2 phase.
Rainey MD; Black EJ; Zachos G; Gillespie DA
Oncogene; 2008 Feb; 27(7):896-906. PubMed ID: 17684483
[TBL] [Abstract][Full Text] [Related]
5. TTK/hMps1 participates in the regulation of DNA damage checkpoint response by phosphorylating CHK2 on threonine 68.
Wei JH; Chou YF; Ou YH; Yeh YH; Tyan SW; Sun TP; Shen CY; Shieh SY
J Biol Chem; 2005 Mar; 280(9):7748-57. PubMed ID: 15618221
[TBL] [Abstract][Full Text] [Related]
6. PML-dependent apoptosis after DNA damage is regulated by the checkpoint kinase hCds1/Chk2.
Yang S; Kuo C; Bisi JE; Kim MK
Nat Cell Biol; 2002 Nov; 4(11):865-70. PubMed ID: 12402044
[TBL] [Abstract][Full Text] [Related]
7. The Drosophila chk2 gene loki is essential for embryonic DNA double-strand-break checkpoints induced in S phase or G2.
Masrouha N; Yang L; Hijal S; Larochelle S; Suter B
Genetics; 2003 Mar; 163(3):973-82. PubMed ID: 12663536
[TBL] [Abstract][Full Text] [Related]
8. DNA damage-induced activation of p53 by the checkpoint kinase Chk2.
Hirao A; Kong YY; Matsuoka S; Wakeham A; Ruland J; Yoshida H; Liu D; Elledge SJ; Mak TW
Science; 2000 Mar; 287(5459):1824-7. PubMed ID: 10710310
[TBL] [Abstract][Full Text] [Related]
9. Chk1 is dispensable for G2 arrest in response to sustained DNA damage when the ATM/p53/p21 pathway is functional.
Lossaint G; Besnard E; Fisher D; Piette J; Dulić V
Oncogene; 2011 Oct; 30(41):4261-74. PubMed ID: 21532626
[TBL] [Abstract][Full Text] [Related]
10. p53 down-regulates CHK1 through p21 and the retinoblastoma protein.
Gottifredi V; Karni-Schmidt O; Shieh SS; Prives C
Mol Cell Biol; 2001 Feb; 21(4):1066-76. PubMed ID: 11158294
[TBL] [Abstract][Full Text] [Related]
11. The Chk2 tumor suppressor is not required for p53 responses in human cancer cells.
Jallepalli PV; Lengauer C; Vogelstein B; Bunz F
J Biol Chem; 2003 Jun; 278(23):20475-9. PubMed ID: 12654917
[TBL] [Abstract][Full Text] [Related]
12. Checking in on Cds1 (Chk2): A checkpoint kinase and tumor suppressor.
McGowan CH
Bioessays; 2002 Jun; 24(6):502-11. PubMed ID: 12111733
[TBL] [Abstract][Full Text] [Related]
13. The human homologs of checkpoint kinases Chk1 and Cds1 (Chk2) phosphorylate p53 at multiple DNA damage-inducible sites.
Shieh SY; Ahn J; Tamai K; Taya Y; Prives C
Genes Dev; 2000 Feb; 14(3):289-300. PubMed ID: 10673501
[TBL] [Abstract][Full Text] [Related]
14. Potentiation of cytotoxicity of topoisomerase i poison by concurrent and sequential treatment with the checkpoint inhibitor UCN-01 involves disparate mechanisms resulting in either p53-independent clonogenic suppression or p53-dependent mitotic catastrophe.
Tse AN; Schwartz GK
Cancer Res; 2004 Sep; 64(18):6635-44. PubMed ID: 15374978
[TBL] [Abstract][Full Text] [Related]
15. UCN-01 inhibits p53 up-regulation and abrogates gamma-radiation-induced G(2)-M checkpoint independently of p53 by targeting both of the checkpoint kinases, Chk2 and Chk1.
Yu Q; La Rose J; Zhang H; Takemura H; Kohn KW; Pommier Y
Cancer Res; 2002 Oct; 62(20):5743-8. PubMed ID: 12384533
[TBL] [Abstract][Full Text] [Related]
16. Chk1 is essential for tumor cell viability following activation of the replication checkpoint.
Cho SH; Toouli CD; Fujii GH; Crain C; Parry D
Cell Cycle; 2005 Jan; 4(1):131-9. PubMed ID: 15539958
[TBL] [Abstract][Full Text] [Related]
17. Topoisomerase inhibitor coralyne photosensitizes DNA, leading to elicitation of Chk2-dependent S-phase checkpoint and p53-independent apoptosis in cancer cells.
Patro BS; Maity B; Chattopadhyay S
Antioxid Redox Signal; 2010 Apr; 12(8):945-60. PubMed ID: 19922265
[TBL] [Abstract][Full Text] [Related]
18. Chk2 is dispensable for p53-mediated G1 arrest but is required for a latent p53-mediated apoptotic response.
Jack MT; Woo RA; Hirao A; Cheung A; Mak TW; Lee PW
Proc Natl Acad Sci U S A; 2002 Jul; 99(15):9825-9. PubMed ID: 12097646
[TBL] [Abstract][Full Text] [Related]
19. Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway.
Chaturvedi P; Eng WK; Zhu Y; Mattern MR; Mishra R; Hurle MR; Zhang X; Annan RS; Lu Q; Faucette LF; Scott GF; Li X; Carr SA; Johnson RK; Winkler JD; Zhou BB
Oncogene; 1999 Jul; 18(28):4047-54. PubMed ID: 10435585
[TBL] [Abstract][Full Text] [Related]
20. Irofulven induces replication-dependent CHK2 activation related to p53 status.
Wang Y; Wiltshire T; Senft J; Reed E; Wang W
Biochem Pharmacol; 2007 Feb; 73(4):469-80. PubMed ID: 17118344
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]
