BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

135 related articles for article (PubMed ID: 11563044)

  • 1. Synthesis and anticancer activity of 4-amino-5-oxo-8-(beta-D-xylofuranosyl)pyrido[2,3-d]pyrimidine.
    Pietrzkowski Z; Girardet JL; Esler C; Wang G
    Nucleosides Nucleotides Nucleic Acids; 2001; 20(4-7):323-8. PubMed ID: 11563044
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Synthesis and cytotoxicity of 4-amino-5-oxopyrido[2,3-d]pyrimidine nucleosides.
    Girardet JL; Gunic E; Esler C; Cieslak D; Pietrzkowski Z; Wang G
    J Med Chem; 2000 Oct; 43(20):3704-13. PubMed ID: 11020285
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase inhibitors and antitumor agents: synthesis and biological activities of 2,4-diamino-5-methyl-6-[(monosubstituted anilino)methyl] pyrido[2,3-d]pyrimidines.
    Gangjee A; Adair O; Queener SF
    J Med Chem; 1999 Jul; 42(13):2447-55. PubMed ID: 10395486
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Synthesis of novel alkyltriazole tagged pyrido[2,3-d]pyrimidine derivatives and their anticancer activity.
    Kurumurthy C; Sambasiva Rao P; Veera Swamy B; Santhosh Kumar G; Shanthan Rao P; Narsaiah B; Velatooru LR; Pamanji R; Venkateswara Rao J
    Eur J Med Chem; 2011 Aug; 46(8):3462-8. PubMed ID: 21632155
    [TBL] [Abstract][Full Text] [Related]  

  • 5. 2,4-diamino-5-deaza-6-substituted pyrido[2,3-d]pyrimidine antifolates as potent and selective nonclassical inhibitors of dihydrofolate reductases.
    Gangjee A; Vasudevan A; Queener SF; Kisliuk RL
    J Med Chem; 1996 Mar; 39(7):1438-46. PubMed ID: 8691474
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Potent in vitro anticancer activities of ring-expanded ("fat") nucleosides containing the imidazo[4,5-e][1,3]diazepine ring system.
    Gill JK; Wang L; Bretner M; Newman R; Kyprianou N; Hosmane RS
    Nucleosides Nucleotides Nucleic Acids; 2001; 20(4-7):1043-5. PubMed ID: 11562954
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Synthesis and antitumor activity of fluorocyclopentenyl-pyrimidines.
    Jeong LS; Zhao LX; Choi WJ; Pal S; Park YH; Lee SK; Chun MW; Lee YB; Ahn CH; Moon HR
    Nucleosides Nucleotides Nucleic Acids; 2007; 26(6-7):713-6. PubMed ID: 18066886
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Synthesis and biological evaluation of 2,4-diamino-6-(arylaminomethyl)pyrido[2,3-d]pyrimidines as inhibitors of Pneumocystis carinii and Toxoplasma gondii dihydrofolate reductase and as antiopportunistic infection and antitumor agents.
    Gangjee A; Adair OO; Queener SF
    J Med Chem; 2003 Nov; 46(23):5074-82. PubMed ID: 14584957
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Synthesis and in vitro evaluation of the anticancer activity of novel fluorinated thiazolo[4, 5-d]pyrimidines.
    Fahmy HT; Rostom SA; Saudi MN; Zjawiony JK; Robins DJ
    Arch Pharm (Weinheim); 2003 Jul; 336(4-5):216-25. PubMed ID: 12916055
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Synthesis of N-{4-[(2,4-diamino-5-methyl-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)thio]benzoyl}-L-glutamic acid and N-{4-[(2-amino-4-oxo-5-methyl-4,7-dihydro-3H-pyrrolo[2,3-d]pyrimidin-6-yl)thio]benzoyl}-L-glutamic acid as dual inhibitors of dihydrofolate reductase and thymidylate synthase and as potential antitumor agents.
    Gangjee A; Lin X; Kisliuk RL; McGuire JJ
    J Med Chem; 2005 Nov; 48(23):7215-22. PubMed ID: 16279780
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Novel 5-substituted, 2,4-diaminofuro[2,3-d]pyrimidines as multireceptor tyrosine kinase and dihydrofolate reductase inhibitors with antiangiogenic and antitumor activity.
    Gangjee A; Zeng Y; Ihnat M; Warnke LA; Green DW; Kisliuk RL; Lin FT
    Bioorg Med Chem; 2005 Sep; 13(18):5475-91. PubMed ID: 16039863
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Tyrosine kinase inhibitors. 15. 4-(Phenylamino)quinazoline and 4-(phenylamino)pyrido[d]pyrimidine acrylamides as irreversible inhibitors of the ATP binding site of the epidermal growth factor receptor.
    Smaill JB; Palmer BD; Rewcastle GW; Denny WA; McNamara DJ; Dobrusin EM; Bridges AJ; Zhou H; Showalter HD; Winters RT; Leopold WR; Fry DW; Nelson JM; Slintak V; Elliot WL; Roberts BJ; Vincent PW; Patmore SJ
    J Med Chem; 1999 May; 42(10):1803-15. PubMed ID: 10346932
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and antitumor activity of pyrido [2,3-d]pyrimidine and pyrido[2,3-d] [1,2,4]triazolo[4,3-a]pyrimidine derivatives that induce apoptosis through G1 cell-cycle arrest.
    Fares M; Abou-Seri SM; Abdel-Aziz HA; Abbas SE; Youssef MM; Eladwy RA
    Eur J Med Chem; 2014 Aug; 83():155-66. PubMed ID: 24956552
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Synthesis of novel thiazolo[4,5-d]pyrimidine derivatives for antimicrobial, anti-HIV and anticancer investigation.
    Rida SM; Habib NS; Badawey EA; Fahmy HT; Ghozlan HA
    Pharmazie; 1996 Dec; 51(12):927-31. PubMed ID: 8985982
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Synthesis of pyrrolo[2,3-d]pyrimidine derivatives and their antiproliferative activity against melanoma cell line.
    Jung MH; Kim H; Choi WK; El-Gamal MI; Park JH; Yoo KH; Sim TB; Lee SH; Baek D; Hah JM; Cho JH; Oh CH
    Bioorg Med Chem Lett; 2009 Dec; 19(23):6538-43. PubMed ID: 19857963
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Synthesis and biological evaluation of novel 2,4,5-substituted pyrimidine derivatives for anticancer activity.
    Xie F; Zhao H; Zhao L; Lou L; Hu Y
    Bioorg Med Chem Lett; 2009 Jan; 19(1):275-8. PubMed ID: 19028425
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Synthesis and cytotoxic activity of new isothiazolo[5,4-d]pyrimidine derivatives.
    Lipnicka U; Regiec A; Machon Z
    Pharmazie; 1994 Sep; 49(9):642-6. PubMed ID: 7972309
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Novel thiophenes, thienopyrimidines, and triazolothienopyrimidines for the evaluation of anticancer and augmentation effects of gamma-radiation.
    Shaaban MA; Ghorab MM; Heiba HI; Kamel MM; Zaher NH; Mostafa MI
    Arch Pharm (Weinheim); 2010 Jul; 343(7):404-10. PubMed ID: 20379969
    [TBL] [Abstract][Full Text] [Related]  

  • 19. An efficient synthesis of 3-fluoro-5-thio-xylofuranosyl nucleosides of thymine, uracil, and 5-fluorouracil as potential antitumor or/and antiviral agents.
    Tsoukala E; Agelis G; Dolinsek J; Botić T; Cencic A; Komiotis D
    Bioorg Med Chem; 2007 May; 15(9):3241-7. PubMed ID: 17337193
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Synthesis and evaluation of 2,7-diamino-thiazolo[4,5-d] pyrimidine analogues as anti-tumor epidermal growth factor receptor (EGFR) tyrosine kinase inhibitors.
    Lin R; Johnson SG; Connolly PJ; Wetter SK; Binnun E; Hughes TV; Murray WV; Pandey NB; Moreno-Mazza SJ; Adams M; Fuentes-Pesquera AR; Middleton SA
    Bioorg Med Chem Lett; 2009 Apr; 19(8):2333-7. PubMed ID: 19286381
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 7.