BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

142 related articles for article (PubMed ID: 11567993)

  • 1. Membrane localization is not required for Mpl function in normal hematopoietic cells.
    Otto KG; Broudy VC; Lin NL; Parganas E; Luthi JN; Drachman JG; Ihle JN; Blau CA
    Blood; 2001 Oct; 98(7):2077-83. PubMed ID: 11567993
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Promegapoietin, a family of chimeric growth factors, supports megakaryocyte development through activation of IL-3 and c-Mpl ligand signaling pathways.
    Doshi PD; Giri JG; Abegg AL; Favara JP; Huynh MS; Kahn LE; Minnerly JC; Pegg LE; Villani-Price D; Siegel NR; Staten NR; Thomas JW; McKearn JP; Smith WG
    Exp Hematol; 2001 Oct; 29(10):1177-84. PubMed ID: 11602319
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Dissecting the thrombopoietin receptor: functional elements of the Mpl cytoplasmic domain.
    Drachman JG; Kaushansky K
    Proc Natl Acad Sci U S A; 1997 Mar; 94(6):2350-5. PubMed ID: 9122198
    [TBL] [Abstract][Full Text] [Related]  

  • 4. A novel MPL point mutation resulting in thrombopoietin-independent activation.
    Abe M; Suzuki K; Inagaki O; Sassa S; Shikama H
    Leukemia; 2002 Aug; 16(8):1500-6. PubMed ID: 12145691
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Thrombopoietin does not induce lineage-restricted commitment of Mpl-R expressing pluripotent progenitors but permits their complete erythroid and megakaryocytic differentiation.
    Goncalves F; Lacout C; Villeval JL; Wendling F; Vainchenker W; Dumenil D
    Blood; 1997 May; 89(10):3544-53. PubMed ID: 9160659
    [TBL] [Abstract][Full Text] [Related]  

  • 6. A new feature of Mpl receptor: ligand-induced transforming activity in FRE rat fibroblasts.
    Challier C; Cocault L; Flon M; Pauchard M; Porteu F; Gisselbrecht S; Souyri M
    Oncogene; 2000 Apr; 19(16):2033-42. PubMed ID: 10803464
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Embryonic stem cell differentiation to hematopoietic cells: A model to study the function of various regions of the intracytoplasmic domain of cytokine receptors in vitro.
    Filippi MD; Porteu F; Le Pesteur F; Rameau P; Nogueira MM; Debili N; Vainchenker W; de Sauvage FJ; Kupperschmitt AD; Sainteny F
    Exp Hematol; 2000 Dec; 28(12):1363-72. PubMed ID: 11146158
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Involvement of prolonged ras activation in thrombopoietin-induced megakaryocytic differentiation of a human factor-dependent hematopoietic cell line.
    Matsumura I; Nakajima K; Wakao H; Hattori S; Hashimoto K; Sugahara H; Kato T; Miyazaki H; Hirano T; Kanakura Y
    Mol Cell Biol; 1998 Jul; 18(7):4282-90. PubMed ID: 9632812
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Hematopoietic-repopulating defects from STAT5-deficient bone marrow are not fully accounted for by loss of thrombopoietin responsiveness.
    Bradley HL; Couldrey C; Bunting KD
    Blood; 2004 Apr; 103(8):2965-72. PubMed ID: 15070672
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Studies with chimeric Mpl/JAK2 receptors indicate that both JAK2 and the membrane-proximal domain of Mpl are required for cellular proliferation.
    Drachman JG; Miyakawa Y; Luthi JN; Dahlen DD; Raney A; Geddis AE; Kaushansky K
    J Biol Chem; 2002 Jun; 277(26):23544-53. PubMed ID: 11980901
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The cytoplasmic domain of Mpl receptor transduces exclusive signals in embryonic and fetal hematopoietic cells.
    Challier C; Cocault L; Berthier R; Binart N; Dusanter-Fourt I; Uzan G; Souyri M
    Blood; 2002 Sep; 100(6):2063-70. PubMed ID: 12200367
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Alteration of c-mpl-mediated signal transduction in CD34(+) cells from patients with myelodysplastic syndromes.
    Kalina U; Hofmann WK; Koschmieder S; Wagner S; Kauschat D; Hoelzer D; Ottmann OG
    Exp Hematol; 2000 Oct; 28(10):1158-63. PubMed ID: 11027834
    [TBL] [Abstract][Full Text] [Related]  

  • 13. The thrombopoietin receptor c-MPL activates JAK2 and TYK2 tyrosine kinases.
    Sattler M; Durstin MA; Frank DA; Okuda K; Kaushansky K; Salgia R; Griffin JD
    Exp Hematol; 1995 Aug; 23(9):1040-8. PubMed ID: 7543416
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Establishment and characterization of the thrombopoietin-dependent megakaryocytic cell line, UT-7/TPO.
    Komatsu N; Kunitama M; Yamada M; Hagiwara T; Kato T; Miyazaki H; Eguchi M; Yamamoto M; Miura Y
    Blood; 1996 Jun; 87(11):4552-60. PubMed ID: 8639823
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Thrombopoietin signaling is required for in vivo expansion of IL-11--responsive hematopoietic progenitor cells in the steady state.
    Scott CL; Robb L; Nandurkar HH; Mansfield R; Alexander WS; Begley CG
    Exp Hematol; 2001 Feb; 29(2):138-45. PubMed ID: 11166452
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Identification of an oncogenic form of the thrombopoietin receptor MPL using retrovirus-mediated gene transfer.
    Onishi M; Mui AL; Morikawa Y; Cho L; Kinoshita S; Nolan GP; Gorman DM; Miyajima A; Kitamura T
    Blood; 1996 Aug; 88(4):1399-406. PubMed ID: 8695859
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Lnk inhibits Tpo-mpl signaling and Tpo-mediated megakaryocytopoiesis.
    Tong W; Lodish HF
    J Exp Med; 2004 Sep; 200(5):569-80. PubMed ID: 15337790
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Expansion of genetically modified primary human hemopoietic cells using chemical inducers of dimerization.
    Richard RE; Wood B; Zeng H; Jin L; Papayannopoulou T; Blau CA
    Blood; 2000 Jan; 95(2):430-6. PubMed ID: 10627446
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Studies of the c-Mpl thrombopoietin receptor through gene disruption and activation.
    Alexander WS; Roberts AW; Maurer AB; Nicola NA; Dunn AR; Metcalf D
    Stem Cells; 1996; 14 Suppl 1():124-32. PubMed ID: 11012212
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Signal transduction by the receptors for thrombopoietin (c-mpL) and interleukin-3 in hematopoietic and nonhematopoietic cells.
    Morella KK; Bruno E; Kumaki S; Lai CF; Fu J; Wang HM; Murray L; Hoffman R; Timour M; BĂ©nit L
    Blood; 1995 Jul; 86(2):557-71. PubMed ID: 7605989
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.