BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

181 related articles for article (PubMed ID: 11584005)

  • 1. Topology of a human equilibrative, nitrobenzylthioinosine (NBMPR)-sensitive nucleoside transporter (hENT1) implicated in the cellular uptake of adenosine and anti-cancer drugs.
    Sundaram M; Yao SY; Ingram JC; Berry ZA; Abidi F; Cass CE; Baldwin SA; Young JD
    J Biol Chem; 2001 Nov; 276(48):45270-5. PubMed ID: 11584005
    [TBL] [Abstract][Full Text] [Related]  

  • 2. A single glycine mutation in the equilibrative nucleoside transporter gene, hENT1, alters nucleoside transport activity and sensitivity to nitrobenzylthioinosine.
    SenGupta DJ; Lum PY; Lai Y; Shubochkina E; Bakken AH; Schneider G; Unadkat JD
    Biochemistry; 2002 Feb; 41(5):1512-9. PubMed ID: 11814344
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Role of cysteine 416 in
    Yao SYM; Ng AML; Cass CE; Young JD
    Biochem J; 2018 Oct; 475(20):3293-3309. PubMed ID: 30254099
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Chimeric constructs between human and rat equilibrative nucleoside transporters (hENT1 and rENT1) reveal hENT1 structural domains interacting with coronary vasoactive drugs.
    Sundaram M; Yao SY; Ng AM; Griffiths M; Cass CE; Baldwin SA; Young JD
    J Biol Chem; 1998 Aug; 273(34):21519-25. PubMed ID: 9705281
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Glycine 154 of the equilibrative nucleoside transporter, hENT1, is important for nucleoside transport and for conferring sensitivity to the inhibitors nitrobenzylthioinosine, dipyridamole, and dilazep.
    SenGupta DJ; Unadkat JD
    Biochem Pharmacol; 2004 Feb; 67(3):453-8. PubMed ID: 15037197
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Molecular cloning and functional characterization of nitrobenzylthioinosine (NBMPR)-sensitive (es) and NBMPR-insensitive (ei) equilibrative nucleoside transporter proteins (rENT1 and rENT2) from rat tissues.
    Yao SY; Ng AM; Muzyka WR; Griffiths M; Cass CE; Baldwin SA; Young JD
    J Biol Chem; 1997 Nov; 272(45):28423-30. PubMed ID: 9353301
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Functional production and reconstitution of the human equilibrative nucleoside transporter (hENT1) in Saccharomyces cerevisiae. Interaction of inhibitors of nucleoside transport with recombinant hENT1 and a glycosylation-defective derivative (hENT1/N48Q).
    Vickers MF; Mani RS; Sundaram M; Hogue DL; Young JD; Baldwin SA; Cass CE
    Biochem J; 1999 Apr; 339 ( Pt 1)(Pt 1):21-32. PubMed ID: 10085223
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Molecular cloning and characterization of a nitrobenzylthioinosine-insensitive (ei) equilibrative nucleoside transporter from human placenta.
    Griffiths M; Yao SY; Abidi F; Phillips SE; Cass CE; Young JD; Baldwin SA
    Biochem J; 1997 Dec; 328 ( Pt 3)(Pt 3):739-43. PubMed ID: 9396714
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Equilibrative nucleoside transporters: mapping regions of interaction for the substrate analogue nitrobenzylthioinosine (NBMPR) using rat chimeric proteins.
    Sundaram M; Yao SY; Ng AM; Cass CE; Baldwin SA; Young JD
    Biochemistry; 2001 Jul; 40(27):8146-51. PubMed ID: 11434784
    [TBL] [Abstract][Full Text] [Related]  

  • 10. N-linked glycosylation of N48 is required for equilibrative nucleoside transporter 1 (ENT1) function.
    Bicket A; Coe IR
    Biosci Rep; 2016 Aug; 36(4):. PubMed ID: 27480168
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Identification of Cys140 in helix 4 as an exofacial cysteine residue within the substrate-translocation channel of rat equilibrative nitrobenzylthioinosine (NBMPR)-insensitive nucleoside transporter rENT2.
    Yao SY; Sundaram M; Chomey EG; Cass CE; Baldwin SA; Young JD
    Biochem J; 2001 Jan; 353(Pt 2):387-93. PubMed ID: 11139404
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Mutation of leucine-92 selectively reduces the apparent affinity of inosine, guanosine, NBMPR [S6-(4-nitrobenzyl)-mercaptopurine riboside] and dilazep for the human equilibrative nucleoside transporter, hENT1.
    Endres CJ; Sengupta DJ; Unadkat JD
    Biochem J; 2004 May; 380(Pt 1):131-7. PubMed ID: 14759222
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Nucleobase transport by human equilibrative nucleoside transporter 1 (hENT1).
    Yao SY; Ng AM; Cass CE; Baldwin SA; Young JD
    J Biol Chem; 2011 Sep; 286(37):32552-62. PubMed ID: 21795683
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Molecular identification of the equilibrative NBMPR-sensitive (es) nucleoside transporter and demonstration of an equilibrative NBMPR-insensitive (ei) transport activity in human erythroleukemia (K562) cells.
    Boleti H; Coe IR; Baldwin SA; Young JD; Cass CE
    Neuropharmacology; 1997 Sep; 36(9):1167-79. PubMed ID: 9364472
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Residues Met89 and Ser160 in the human equilibrative nucleoside transporter 1 affect its affinity for adenosine, guanosine, S6-(4-nitrobenzyl)-mercaptopurine riboside, and dipyridamole.
    Endres CJ; Unadkat JD
    Mol Pharmacol; 2005 Mar; 67(3):837-44. PubMed ID: 15557207
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Equilibrative nucleoside transporter 2 is expressed in human umbilical vein endothelium, but is not involved in the inhibition of adenosine transport induced by hyperglycaemia.
    Aguayo C; Casado J; González M; Pearson JD; Martín RS; Casanello P; Pastor-Anglada M; Sobrevia L
    Placenta; 2005; 26(8-9):641-53. PubMed ID: 16085043
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Transport of antiviral 3'-deoxy-nucleoside drugs by recombinant human and rat equilibrative, nitrobenzylthioinosine (NBMPR)-insensitive (ENT2) nucleoside transporter proteins produced in Xenopus oocytes.
    Yao SY; Ng AM; Sundaram M; Cass CE; Baldwin SA; Young JD
    Mol Membr Biol; 2001; 18(2):161-7. PubMed ID: 11463208
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Structures of human ENT1 in complex with adenosine reuptake inhibitors.
    Wright NJ; Lee SY
    Nat Struct Mol Biol; 2019 Jul; 26(7):599-606. PubMed ID: 31235912
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Transport of A1 adenosine receptor agonist tecadenoson by human and mouse nucleoside transporters: evidence for blood-brain barrier transport by murine equilibrative nucleoside transporter 1 mENT1.
    Lepist EI; Damaraju VL; Zhang J; Gati WP; Yao SY; Smith KM; Karpinski E; Young JD; Leung KH; Cass CE
    Drug Metab Dispos; 2013 Apr; 41(4):916-22. PubMed ID: 23388705
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Kinetic and pharmacological properties of cloned human equilibrative nucleoside transporters, ENT1 and ENT2, stably expressed in nucleoside transporter-deficient PK15 cells. Ent2 exhibits a low affinity for guanosine and cytidine but a high affinity for inosine.
    Ward JL; Sherali A; Mo ZP; Tse CM
    J Biol Chem; 2000 Mar; 275(12):8375-81. PubMed ID: 10722669
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 10.