These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

147 related articles for article (PubMed ID: 11585447)

  • 1. Are free energy calculations useful in practice? A comparison with rapid scoring functions for the p38 MAP kinase protein system.
    Pearlman DA; Charifson PS
    J Med Chem; 2001 Oct; 44(21):3417-23. PubMed ID: 11585447
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Evaluating the molecular mechanics poisson-boltzmann surface area free energy method using a congeneric series of ligands to p38 MAP kinase.
    Pearlman DA
    J Med Chem; 2005 Dec; 48(24):7796-807. PubMed ID: 16302819
    [TBL] [Abstract][Full Text] [Related]  

  • 3. A detailed comparison of current docking and scoring methods on systems of pharmaceutical relevance.
    Perola E; Walters WP; Charifson PS
    Proteins; 2004 Aug; 56(2):235-49. PubMed ID: 15211508
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Improved scoring of ligand-protein interactions using OWFEG free energy grids.
    Pearlman DA; Charifson PS
    J Med Chem; 2001 Feb; 44(4):502-11. PubMed ID: 11170640
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Hybrid-designed inhibitors of p38 MAP kinase utilizing N-arylpyridazinones.
    Colletti SL; Frie JL; Dixon EC; Singh SB; Choi BK; Scapin G; Fitzgerald CE; Kumar S; Nichols EA; O'Keefe SJ; O'Neill EA; Porter G; Samuel K; Schmatz DM; Schwartz CD; Shoop WL; Thompson CM; Thompson JE; Wang R; Woods A; Zaller DM; Doherty JB
    J Med Chem; 2003 Jan; 46(3):349-52. PubMed ID: 12540232
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Synthesis of imidazo[2,1-a]phthalazines, potential inhibitors of p38 MAP kinase. Prediction of binding affinities of protein ligands.
    Mavel S; Thery I; Gueiffier A
    Arch Pharm (Weinheim); 2002 Jan; 335(1):7-14. PubMed ID: 11933680
    [TBL] [Abstract][Full Text] [Related]  

  • 7. FURSMASA: a new approach to rapid scoring functions that uses a MD-averaged potential energy grid and a solvent-accessible surface area term with parameters GA fit to experimental data.
    Pearlman DA; Rao BG; Charifson P
    Proteins; 2008 May; 71(3):1519-38. PubMed ID: 18300249
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Modified AutoDock for accurate docking of protein kinase inhibitors.
    Buzko OV; Bishop AC; Shokat KM
    J Comput Aided Mol Des; 2002 Feb; 16(2):113-27. PubMed ID: 12188021
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Thermal denaturation: a method to rank slow binding, high-affinity P38alpha MAP kinase inhibitors.
    Kroe RR; Regan J; Proto A; Peet GW; Roy T; Landro LD; Fuschetto NG; Pargellis CA; Ingraham RH
    J Med Chem; 2003 Oct; 46(22):4669-75. PubMed ID: 14561086
    [TBL] [Abstract][Full Text] [Related]  

  • 10. Computational sampling of a cryptic drug binding site in a protein receptor: explicit solvent molecular dynamics and inhibitor docking to p38 MAP kinase.
    Frembgen-Kesner T; Elcock AH
    J Mol Biol; 2006 May; 359(1):202-14. PubMed ID: 16616932
    [TBL] [Abstract][Full Text] [Related]  

  • 11. General model for estimation of the inhibition of protein kinases using Monte Carlo simulations.
    Tominaga Y; Jorgensen WL
    J Med Chem; 2004 May; 47(10):2534-49. PubMed ID: 15115396
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Free-energy force-field three-dimensional quantitative structure-activity relationship analysis of a set of p38-mitogen activated protein kinase inhibitors.
    Romeiro NC; Albuquerque MG; de Alencastro RB; Ravi M; Hopfinger AJ
    J Mol Model; 2006 Sep; 12(6):855-68. PubMed ID: 16541250
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Synthesis and activity of new aryl- and heteroaryl-substituted pyrazole inhibitors of the transforming growth factor-beta type I receptor kinase domain.
    Sawyer JS; Anderson BD; Beight DW; Campbell RM; Jones ML; Herron DK; Lampe JW; McCowan JR; McMillen WT; Mort N; Parsons S; Smith EC; Vieth M; Weir LC; Yan L; Zhang F; Yingling JM
    J Med Chem; 2003 Sep; 46(19):3953-6. PubMed ID: 12954047
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Structural basis for p38alpha MAP kinase quinazolinone and pyridol-pyrimidine inhibitor specificity.
    Fitzgerald CE; Patel SB; Becker JW; Cameron PM; Zaller D; Pikounis VB; O'Keefe SJ; Scapin G
    Nat Struct Biol; 2003 Sep; 10(9):764-9. PubMed ID: 12897767
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Kinetics of small molecule inhibitor binding to p38 kinase.
    Thurmond RL; Wadsworth SA; Schafer PH; Zivin RA; Siekierka JJ
    Eur J Biochem; 2001 Nov; 268(22):5747-54. PubMed ID: 11722559
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Investigations of neurotrophic inhibitors of FK506 binding protein via Monte Carlo simulations.
    Lamb ML; Jorgensen WL
    J Med Chem; 1998 Oct; 41(21):3928-39. PubMed ID: 9767630
    [TBL] [Abstract][Full Text] [Related]  

  • 17. BREED: Generating novel inhibitors through hybridization of known ligands. Application to CDK2, p38, and HIV protease.
    Pierce AC; Rao G; Bemis GW
    J Med Chem; 2004 May; 47(11):2768-75. PubMed ID: 15139755
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Protein-ligand binding affinity predictions by implicit solvent simulations: a tool for lead optimization?
    Michel J; Verdonk ML; Essex JW
    J Med Chem; 2006 Dec; 49(25):7427-39. PubMed ID: 17149872
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Coordinate signaling by Src and p38 kinases in the induction of cortical cataracts.
    Zhou J; Menko AS
    Invest Ophthalmol Vis Sci; 2004 Jul; 45(7):2314-23. PubMed ID: 15223811
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Elevated levels of cyclooxygenase-2 in antigen-stimulated mast cells is associated with minimal activation of p38 mitogen-activated protein kinase.
    Hundley TR; Prasad AR; Beaven MA
    J Immunol; 2001 Aug; 167(3):1629-36. PubMed ID: 11466386
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 8.