BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

972 related articles for article (PubMed ID: 11585742)

  • 1. Methylated CpG dinucleotides are the preferential targets for G-to-T transversion mutations induced by benzo[a]pyrene diol epoxide in mammalian cells: similarities with the p53 mutation spectrum in smoking-associated lung cancers.
    Yoon JH; Smith LE; Feng Z; Tang M; Lee CS; Pfeifer GP
    Cancer Res; 2001 Oct; 61(19):7110-7. PubMed ID: 11585742
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Mutability of p53 hotspot codons to benzo(a)pyrene diol epoxide (BPDE) and the frequency of p53 mutations in nontumorous human lung.
    Hussain SP; Amstad P; Raja K; Sawyer M; Hofseth L; Shields PG; Hewer A; Phillips DH; Ryberg D; Haugen A; Harris CC
    Cancer Res; 2001 Sep; 61(17):6350-5. PubMed ID: 11522624
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Similarities in sunlight-induced mutational spectra of CpG-methylated transgenes and the p53 gene in skin cancer point to an important role of 5-methylcytosine residues in solar UV mutagenesis.
    You YH; Pfeifer GP
    J Mol Biol; 2001 Jan; 305(3):389-99. PubMed ID: 11152598
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Formation of diastereomeric benzo[a]pyrene diol epoxide-guanine adducts in p53 gene-derived DNA sequences.
    Matter B; Wang G; Jones R; Tretyakova N
    Chem Res Toxicol; 2004 Jun; 17(6):731-41. PubMed ID: 15206894
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mutational signature of the proximate bladder carcinogen N-hydroxy-4-acetylaminobiphenyl: inconsistency with the p53 mutational spectrum in bladder cancer.
    Besaratinia A; Bates SE; Pfeifer GP
    Cancer Res; 2002 Aug; 62(15):4331-8. PubMed ID: 12154037
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Involvement of 5-methylcytosine in sunlight-induced mutagenesis.
    You YH; Li C; Pfeifer GP
    J Mol Biol; 1999 Oct; 293(3):493-503. PubMed ID: 10543945
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Slow repair of bulky DNA adducts along the nontranscribed strand of the human p53 gene may explain the strand bias of transversion mutations in cancers.
    Denissenko MF; Pao A; Pfeifer GP; Tang M
    Oncogene; 1998 Mar; 16(10):1241-7. PubMed ID: 9546425
    [TBL] [Abstract][Full Text] [Related]  

  • 8. 1,3-butadiene: cancer, mutations, and adducts. Part II: Roles of two metabolites of 1,3-butadiene in mediating its in vivo genotoxicity.
    Recio L; Saranko CJ; Steen AM
    Res Rep Health Eff Inst; 2000 Mar; (92):49-87; discussion 141-9. PubMed ID: 10925839
    [TBL] [Abstract][Full Text] [Related]  

  • 9. Use of UvrABC nuclease to quantify benzo[a]pyrene diol epoxide-DNA adduct formation at methylated versus unmethylated CpG sites in the p53 gene.
    Tang MS; Zheng JB; Denissenko MF; Pfeifer GP; Zheng Y
    Carcinogenesis; 1999 Jun; 20(6):1085-9. PubMed ID: 10357792
    [TBL] [Abstract][Full Text] [Related]  

  • 10. DNA damage and mutations produced by chloroacetaldehyde in a CpG-methylated target gene.
    Choi JH; Pfeifer GP
    Mutat Res; 2004 Dec; 568(2):245-56. PubMed ID: 15542111
    [TBL] [Abstract][Full Text] [Related]  

  • 11. Enhancement of the mutagenicity of benzo(a)pyrene diol epoxide by a nonmutagenic dose of ultraviolet A radiation.
    Besaratinia A; Pfeifer GP
    Cancer Res; 2003 Dec; 63(24):8708-16. PubMed ID: 14695185
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Comparison of mutations in the p53 and K-ras genes in lung carcinomas from smoking and nonsmoking women.
    Gealy R; Zhang L; Siegfried JM; Luketich JD; Keohavong P
    Cancer Epidemiol Biomarkers Prev; 1999 Apr; 8(4 Pt 1):297-302. PubMed ID: 10207632
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Mutagenic potential of benzo[a]pyrene-derived DNA adducts positioned in codon 273 of the human P53 gene.
    Dong H; Bonala RR; Suzuki N; Johnson F; Grollman AP; Shibutani S
    Biochemistry; 2004 Dec; 43(50):15922-8. PubMed ID: 15595848
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Mutagenic response of the endogenous hprt gene and lacI transgene in benzo[a]pyrene-treated Big Blue B6C3F1 mice.
    Skopek TR; Kort KL; Marino DR; Mittal LV; Umbenhauer DR; Laws GM; Adams SP
    Environ Mol Mutagen; 1996; 28(4):376-84. PubMed ID: 8991066
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Arsenite enhances the benzo[a]pyrene diol epoxide (BPDE)-induced mutagenesis with no marked effect on repair of BPDE-DNA adducts in human lung cells.
    Chiang HC; Tsou TC
    Toxicol In Vitro; 2009 Aug; 23(5):897-905. PubMed ID: 19470404
    [TBL] [Abstract][Full Text] [Related]  

  • 16. In silico p53 mutation hotspots in lung cancer.
    Lewis PD; Parry JM
    Carcinogenesis; 2004 Jul; 25(7):1099-107. PubMed ID: 14729588
    [TBL] [Abstract][Full Text] [Related]  

  • 17. DNA damage, repair, and mutation induction by (+)-Syn and (-)-anti-dibenzo[a,l]pyrene-11,12-diol-13,14-epoxides in mouse cells.
    Yoon JH; Besaratinia A; Feng Z; Tang MS; Amin S; Luch A; Pfeifer GP
    Cancer Res; 2004 Oct; 64(20):7321-8. PubMed ID: 15492252
    [TBL] [Abstract][Full Text] [Related]  

  • 18. Preferential carcinogen-DNA adduct formation at codons 12 and 14 in the human K-ras gene and their possible mechanisms.
    Hu W; Feng Z; Tang MS
    Biochemistry; 2003 Aug; 42(33):10012-23. PubMed ID: 12924950
    [TBL] [Abstract][Full Text] [Related]  

  • 19. Formation of benzo[a]pyrene diol epoxide-DNA adducts at specific guanines within K-ras and p53 gene sequences: stable isotope-labeling mass spectrometry approach.
    Tretyakova N; Matter B; Jones R; Shallop A
    Biochemistry; 2002 Jul; 41(30):9535-44. PubMed ID: 12135376
    [TBL] [Abstract][Full Text] [Related]  

  • 20. p53 mutations in lung cancer following radiation therapy for Hodgkin's disease.
    De Benedetti VM; Travis LB; Welsh JA; van Leeuwen FE; Stovall M; Clarke EA; Boice JD; Bennett WP
    Cancer Epidemiol Biomarkers Prev; 1996 Feb; 5(2):93-8. PubMed ID: 8850268
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 49.