BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

4238 related articles for article (PubMed ID: 11585776)

  • 21. Association of hypoxia-inducible factors 1alpha and 2alpha with activated angiogenic pathways and prognosis in patients with endometrial carcinoma.
    Sivridis E; Giatromanolaki A; Gatter KC; Harris AL; Koukourakis MI;
    Cancer; 2002 Sep; 95(5):1055-63. PubMed ID: 12209691
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Loss of von Hippel-Lindau protein causes cell density dependent deregulation of CyclinD1 expression through hypoxia-inducible factor.
    Baba M; Hirai S; Yamada-Okabe H; Hamada K; Tabuchi H; Kobayashi K; Kondo K; Yoshida M; Yamashita A; Kishida T; Nakaigawa N; Nagashima Y; Kubota Y; Yao M; Ohno S
    Oncogene; 2003 May; 22(18):2728-38. PubMed ID: 12743597
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Renal cancer cells lacking hypoxia inducible factor (HIF)-1alpha expression maintain vascular endothelial growth factor expression through HIF-2alpha.
    Shinojima T; Oya M; Takayanagi A; Mizuno R; Shimizu N; Murai M
    Carcinogenesis; 2007 Mar; 28(3):529-36. PubMed ID: 16920734
    [TBL] [Abstract][Full Text] [Related]  

  • 24. The redox protein thioredoxin-1 (Trx-1) increases hypoxia-inducible factor 1alpha protein expression: Trx-1 overexpression results in increased vascular endothelial growth factor production and enhanced tumor angiogenesis.
    Welsh SJ; Bellamy WT; Briehl MM; Powis G
    Cancer Res; 2002 Sep; 62(17):5089-95. PubMed ID: 12208766
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Hypoxia-induced gene expression occurs solely through the action of hypoxia-inducible factor 1alpha (HIF-1alpha): role of cytoplasmic trapping of HIF-2alpha.
    Park SK; Dadak AM; Haase VH; Fontana L; Giaccia AJ; Johnson RS
    Mol Cell Biol; 2003 Jul; 23(14):4959-71. PubMed ID: 12832481
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Loss of PTEN facilitates HIF-1-mediated gene expression.
    Zundel W; Schindler C; Haas-Kogan D; Koong A; Kaper F; Chen E; Gottschalk AR; Ryan HE; Johnson RS; Jefferson AB; Stokoe D; Giaccia AJ
    Genes Dev; 2000 Feb; 14(4):391-6. PubMed ID: 10691731
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Reversion of deregulated expression of vascular endothelial growth factor in human renal carcinoma cells by von Hippel-Lindau tumor suppressor protein.
    Siemeister G; Weindel K; Mohrs K; Barleon B; Martiny-Baron G; Marmé D
    Cancer Res; 1996 May; 56(10):2299-301. PubMed ID: 8625303
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Expression of hypoxia-inducible factors in human renal cancer: relationship to angiogenesis and to the von Hippel-Lindau gene mutation.
    Turner KJ; Moore JW; Jones A; Taylor CF; Cuthbert-Heavens D; Han C; Leek RD; Gatter KC; Maxwell PH; Ratcliffe PJ; Cranston D; Harris AL
    Cancer Res; 2002 May; 62(10):2957-61. PubMed ID: 12019178
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Identification of novel hypoxia dependent and independent target genes of the von Hippel-Lindau (VHL) tumour suppressor by mRNA differential expression profiling.
    Wykoff CC; Pugh CW; Maxwell PH; Harris AL; Ratcliffe PJ
    Oncogene; 2000 Dec; 19(54):6297-305. PubMed ID: 11175344
    [TBL] [Abstract][Full Text] [Related]  

  • 30. BCR/ABL induces expression of vascular endothelial growth factor and its transcriptional activator, hypoxia inducible factor-1alpha, through a pathway involving phosphoinositide 3-kinase and the mammalian target of rapamycin.
    Mayerhofer M; Valent P; Sperr WR; Griffin JD; Sillaber C
    Blood; 2002 Nov; 100(10):3767-75. PubMed ID: 12393646
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Podocyte expression of hypoxia-inducible factor (HIF)-1 and HIF-2 during glomerular development.
    Freeburg PB; Robert B; St John PL; Abrahamson DR
    J Am Soc Nephrol; 2003 Apr; 14(4):927-38. PubMed ID: 12660327
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Contrasting effects on HIF-1alpha regulation by disease-causing pVHL mutations correlate with patterns of tumourigenesis in von Hippel-Lindau disease.
    Clifford SC; Cockman ME; Smallwood AC; Mole DR; Woodward ER; Maxwell PH; Ratcliffe PJ; Maher ER
    Hum Mol Genet; 2001 May; 10(10):1029-38. PubMed ID: 11331613
    [TBL] [Abstract][Full Text] [Related]  

  • 33. A hypoxia-independent hypoxia-inducible factor-1 activation pathway induced by phosphatidylinositol-3 kinase/Akt in HER2 overexpressing cells.
    Li YM; Zhou BP; Deng J; Pan Y; Hay N; Hung MC
    Cancer Res; 2005 Apr; 65(8):3257-63. PubMed ID: 15833858
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Vascular endothelial growth factor transcriptional activation is mediated by hypoxia-inducible factor 1alpha, HDM2, and p70S6K1 in response to phosphatidylinositol 3-kinase/AKT signaling.
    Skinner HD; Zheng JZ; Fang J; Agani F; Jiang BH
    J Biol Chem; 2004 Oct; 279(44):45643-51. PubMed ID: 15337760
    [TBL] [Abstract][Full Text] [Related]  

  • 35. VEGF production by primary human renal proximal tubular cells: requirement of HIF-1, PI3-kinase and MAPKK-1 signaling.
    Hellwig-Bürgel T; Stiehl DP; Katschinski DM; Marxsen J; Kreft B; Jelkmann W
    Cell Physiol Biochem; 2005; 15(1-4):99-108. PubMed ID: 15665520
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Insulin stimulates hypoxia-inducible factor 1 through a phosphatidylinositol 3-kinase/target of rapamycin-dependent signaling pathway.
    Treins C; Giorgetti-Peraldi S; Murdaca J; Semenza GL; Van Obberghen E
    J Biol Chem; 2002 Aug; 277(31):27975-81. PubMed ID: 12032158
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma.
    Raval RR; Lau KW; Tran MG; Sowter HM; Mandriota SJ; Li JL; Pugh CW; Maxwell PH; Harris AL; Ratcliffe PJ
    Mol Cell Biol; 2005 Jul; 25(13):5675-86. PubMed ID: 15964822
    [TBL] [Abstract][Full Text] [Related]  

  • 38. PI3K/Akt is required for heat shock proteins to protect hypoxia-inducible factor 1alpha from pVHL-independent degradation.
    Zhou J; Schmid T; Frank R; Brüne B
    J Biol Chem; 2004 Apr; 279(14):13506-13. PubMed ID: 14726529
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Arsenite induces HIF-1alpha and VEGF through PI3K, Akt and reactive oxygen species in DU145 human prostate carcinoma cells.
    Gao N; Shen L; Zhang Z; Leonard SS; He H; Zhang XG; Shi X; Jiang BH
    Mol Cell Biochem; 2004 Jan; 255(1-2):33-45. PubMed ID: 14971644
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Angiogenesis: how a tumor adapts to hypoxia.
    Richard DE; Berra E; Pouysségur J
    Biochem Biophys Res Commun; 1999 Dec; 266(3):718-22. PubMed ID: 10603309
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 212.