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6. Proteasome inhibition in cancer: development of PS-341. Adams J Semin Oncol; 2001 Dec; 28(6):613-9. PubMed ID: 11740819 [TBL] [Abstract][Full Text] [Related]
7. Promoting proteasomes: trash to treasure. Sussman HE Drug Discov Today; 2003 Oct; 8(19):866-8. PubMed ID: 14554007 [No Abstract] [Full Text] [Related]
8. Protease inhibitor-induced apoptosis: accumulation of wt p53, p21WAF1/CIP1, and induction of apoptosis are independent markers of proteasome inhibition. An WG; Hwang SG; Trepel JB; Blagosklonny MV Leukemia; 2000 Jul; 14(7):1276-83. PubMed ID: 10914553 [TBL] [Abstract][Full Text] [Related]
9. Apoptosis meets proteasome, an invaluable therapeutic target of anticancer drugs. Giuliano M; D'Anneo A; De Blasio A; Vento R; Tesoriere G Ital J Biochem; 2003 Jun; 52(2):112-21. PubMed ID: 14677428 [TBL] [Abstract][Full Text] [Related]
10. Potential for proteasome inhibition in the treatment of cancer. Adams J Drug Discov Today; 2003 Apr; 8(7):307-15. PubMed ID: 12654543 [TBL] [Abstract][Full Text] [Related]
11. Effects of the proteasome inhibitor PS-341 on tumor growth in HTLV-1 Tax transgenic mice and Tax tumor transplants. Mitra-Kaushik S; Harding JC; Hess JL; Ratner L Blood; 2004 Aug; 104(3):802-9. PubMed ID: 15090453 [TBL] [Abstract][Full Text] [Related]
12. Human somatic cell knockouts reveal determinants of sensitivity and resistance to proteasome inhibitor PS-341. Lee C; Waldman T Cancer Biol Ther; 2003; 2(6):700-1. PubMed ID: 14688480 [No Abstract] [Full Text] [Related]
13. The role of the ubiquitination-proteasome pathway in breast cancer: applying drugs that affect the ubiquitin-proteasome pathway to the therapy of breast cancer. Orlowski RZ; Dees EC Breast Cancer Res; 2003; 5(1):1-7. PubMed ID: 12559038 [TBL] [Abstract][Full Text] [Related]
14. PS-341, a novel proteasome inhibitor, induces Bcl-2 phosphorylation and cleavage in association with G2-M phase arrest and apoptosis. Ling YH; Liebes L; Ng B; Buckley M; Elliott PJ; Adams J; Jiang JD; Muggia FM; Perez-Soler R Mol Cancer Ther; 2002 Aug; 1(10):841-9. PubMed ID: 12492117 [TBL] [Abstract][Full Text] [Related]
15. Development of the proteasome inhibitor Velcade (Bortezomib). Adams J; Kauffman M Cancer Invest; 2004; 22(2):304-11. PubMed ID: 15199612 [TBL] [Abstract][Full Text] [Related]
16. Differential effects of the proteasome inhibitor bortezomib on apoptosis and angiogenesis in human prostate tumor xenografts. Williams S; Pettaway C; Song R; Papandreou C; Logothetis C; McConkey DJ Mol Cancer Ther; 2003 Sep; 2(9):835-43. PubMed ID: 14555702 [TBL] [Abstract][Full Text] [Related]
17. Proteasome inhibitors potentiate leukemic cell apoptosis induced by the cyclin-dependent kinase inhibitor flavopiridol through a SAPK/JNK- and NF-kappaB-dependent process. Dai Y; Rahmani M; Grant S Oncogene; 2003 Oct; 22(46):7108-22. PubMed ID: 14562039 [TBL] [Abstract][Full Text] [Related]
18. Mechanisms of proteasome inhibitor PS-341-induced G(2)-M-phase arrest and apoptosis in human non-small cell lung cancer cell lines. Ling YH; Liebes L; Jiang JD; Holland JF; Elliott PJ; Adams J; Muggia FM; Perez-Soler R Clin Cancer Res; 2003 Mar; 9(3):1145-54. PubMed ID: 12631620 [TBL] [Abstract][Full Text] [Related]
19. Effects of the proteasome inhibitor, bortezomib, on apoptosis in isolated lymphocytes obtained from patients with chronic lymphocytic leukemia. Pahler JC; Ruiz S; Niemer I; Calvert LR; Andreeff M; Keating M; Faderl S; McConkey DJ Clin Cancer Res; 2003 Oct; 9(12):4570-7. PubMed ID: 14555532 [TBL] [Abstract][Full Text] [Related]
20. Targeting the ubiquitin-proteasome pathway in breast cancer. Cardoso F; Ross JS; Picart MJ; Sotiriou C; Durbecq V Clin Breast Cancer; 2004 Jun; 5(2):148-57. PubMed ID: 15245620 [TBL] [Abstract][Full Text] [Related] [Next] [New Search]