BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

559 related articles for article (PubMed ID: 11593023)

  • 1. DNA ligase IV-deficient cells are more resistant to ionizing radiation in the absence of Ku70: Implications for DNA double-strand break repair.
    Adachi N; Ishino T; Ishii Y; Takeda S; Koyama H
    Proc Natl Acad Sci U S A; 2001 Oct; 98(21):12109-13. PubMed ID: 11593023
    [TBL] [Abstract][Full Text] [Related]  

  • 2. Alternative end-joining catalyzes class switch recombination in the absence of both Ku70 and DNA ligase 4.
    Boboila C; Yan C; Wesemann DR; Jankovic M; Wang JH; Manis J; Nussenzweig A; Nussenzweig M; Alt FW
    J Exp Med; 2010 Feb; 207(2):417-27. PubMed ID: 20142431
    [TBL] [Abstract][Full Text] [Related]  

  • 3. Ku70 suppresses alternative end joining in G1-arrested progenitor B cells.
    Liang Z; Kumar V; Le Bouteiller M; Zurita J; Kenrick J; Lin SG; Lou J; Hu J; Ye AY; Boboila C; Alt FW; Frock RL
    Proc Natl Acad Sci U S A; 2021 May; 118(21):. PubMed ID: 34006647
    [TBL] [Abstract][Full Text] [Related]  

  • 4. Homologous recombination and non-homologous end-joining pathways of DNA double-strand break repair have overlapping roles in the maintenance of chromosomal integrity in vertebrate cells.
    Takata M; Sasaki MS; Sonoda E; Morrison C; Hashimoto M; Utsumi H; Yamaguchi-Iwai Y; Shinohara A; Takeda S
    EMBO J; 1998 Sep; 17(18):5497-508. PubMed ID: 9736627
    [TBL] [Abstract][Full Text] [Related]  

  • 5. Mechanisms of DNA double strand break repair and chromosome aberration formation.
    Iliakis G; Wang H; Perrault AR; Boecker W; Rosidi B; Windhofer F; Wu W; Guan J; Terzoudi G; Pantelias G
    Cytogenet Genome Res; 2004; 104(1-4):14-20. PubMed ID: 15162010
    [TBL] [Abstract][Full Text] [Related]  

  • 6. Repair of radiation induced DNA double strand breaks by backup NHEJ is enhanced in G2.
    Wu W; Wang M; Wu W; Singh SK; Mussfeldt T; Iliakis G
    DNA Repair (Amst); 2008 Feb; 7(2):329-38. PubMed ID: 18155970
    [TBL] [Abstract][Full Text] [Related]  

  • 7. Genetic analysis of the DNA-dependent protein kinase reveals an inhibitory role of Ku in late S-G2 phase DNA double-strand break repair.
    Fukushima T; Takata M; Morrison C; Araki R; Fujimori A; Abe M; Tatsumi K; Jasin M; Dhar PK; Sonoda E; Chiba T; Takeda S
    J Biol Chem; 2001 Nov; 276(48):44413-8. PubMed ID: 11577093
    [TBL] [Abstract][Full Text] [Related]  

  • 8. Parp-1 protects homologous recombination from interference by Ku and Ligase IV in vertebrate cells.
    Hochegger H; Dejsuphong D; Fukushima T; Morrison C; Sonoda E; Schreiber V; Zhao GY; Saberi A; Masutani M; Adachi N; Koyama H; de Murcia G; Takeda S
    EMBO J; 2006 Mar; 25(6):1305-14. PubMed ID: 16498404
    [TBL] [Abstract][Full Text] [Related]  

  • 9. 53BP1 contributes to survival of cells irradiated with X-ray during G1 without Ku70 or Artemis.
    Iwabuchi K; Hashimoto M; Matsui T; Kurihara T; Shimizu H; Adachi N; Ishiai M; Yamamoto K; Tauchi H; Takata M; Koyama H; Date T
    Genes Cells; 2006 Aug; 11(8):935-48. PubMed ID: 16866876
    [TBL] [Abstract][Full Text] [Related]  

  • 10. The non-homologous end-joining pathway is not involved in the radiosensitization of mammalian cells by heat shock.
    Dynlacht JR; Bittner ME; Bethel JA; Beck BD
    J Cell Physiol; 2003 Sep; 196(3):557-64. PubMed ID: 12891712
    [TBL] [Abstract][Full Text] [Related]  

  • 11. The Drosophila melanogaster DNA Ligase IV gene plays a crucial role in the repair of radiation-induced DNA double-strand breaks and acts synergistically with Rad54.
    Gorski MM; Eeken JC; de Jong AW; Klink I; Loos M; Romeijn RJ; van Veen BL; Mullenders LH; Ferro W; Pastink A
    Genetics; 2003 Dec; 165(4):1929-41. PubMed ID: 14704177
    [TBL] [Abstract][Full Text] [Related]  

  • 12. Genetic evidence for involvement of two distinct nonhomologous end-joining pathways in repair of topoisomerase II-mediated DNA damage.
    Adachi N; Iiizumi S; So S; Koyama H
    Biochem Biophys Res Commun; 2004 Jun; 318(4):856-61. PubMed ID: 15147950
    [TBL] [Abstract][Full Text] [Related]  

  • 13. Genetic interactions between ATM and the nonhomologous end-joining factors in genomic stability and development.
    Sekiguchi J; Ferguson DO; Chen HT; Yang EM; Earle J; Frank K; Whitlow S; Gu Y; Xu Y; Nussenzweig A; Alt FW
    Proc Natl Acad Sci U S A; 2001 Mar; 98(6):3243-8. PubMed ID: 11248063
    [TBL] [Abstract][Full Text] [Related]  

  • 14. Ku protein stimulates DNA end joining by mammalian DNA ligases: a direct role for Ku in repair of DNA double-strand breaks.
    Ramsden DA; Gellert M
    EMBO J; 1998 Jan; 17(2):609-14. PubMed ID: 9430651
    [TBL] [Abstract][Full Text] [Related]  

  • 15. Novel functional requirements for non-homologous DNA end joining in Schizosaccharomyces pombe.
    Manolis KG; Nimmo ER; Hartsuiker E; Carr AM; Jeggo PA; Allshire RC
    EMBO J; 2001 Jan; 20(1-2):210-21. PubMed ID: 11226171
    [TBL] [Abstract][Full Text] [Related]  

  • 16. Different types of V(D)J recombination and end-joining defects in DNA double-strand break repair mutant mammalian cells.
    Verkaik NS; Esveldt-van Lange RE; van Heemst D; Brüggenwirth HT; Hoeijmakers JH; Zdzienicka MZ; van Gent DC
    Eur J Immunol; 2002 Mar; 32(3):701-9. PubMed ID: 11870614
    [TBL] [Abstract][Full Text] [Related]  

  • 17. Alternative end-joining catalyzes robust IgH locus deletions and translocations in the combined absence of ligase 4 and Ku70.
    Boboila C; Jankovic M; Yan CT; Wang JH; Wesemann DR; Zhang T; Fazeli A; Feldman L; Nussenzweig A; Nussenzweig M; Alt FW
    Proc Natl Acad Sci U S A; 2010 Feb; 107(7):3034-9. PubMed ID: 20133803
    [TBL] [Abstract][Full Text] [Related]  

  • 18. The embryonic lethality in DNA ligase IV-deficient mice is rescued by deletion of Ku: implications for unifying the heterogeneous phenotypes of NHEJ mutants.
    Karanjawala ZE; Adachi N; Irvine RA; Oh EK; Shibata D; Schwarz K; Hsieh CL; Lieber MR
    DNA Repair (Amst); 2002 Dec; 1(12):1017-26. PubMed ID: 12531011
    [TBL] [Abstract][Full Text] [Related]  

  • 19. C-Terminal region of DNA ligase IV drives XRCC4/DNA ligase IV complex to chromatin.
    Liu S; Liu X; Kamdar RP; Wanotayan R; Sharma MK; Adachi N; Matsumoto Y
    Biochem Biophys Res Commun; 2013 Sep; 439(2):173-8. PubMed ID: 23994631
    [TBL] [Abstract][Full Text] [Related]  

  • 20. Deficiency of ligase IV leads to reduced NHEJ, accumulation of DNA damage, and can sensitize cells to cancer therapeutics.
    Kumari N; Antil H; Kumari S; Raghavan SC
    Genomics; 2023 Nov; 115(6):110731. PubMed ID: 37871849
    [TBL] [Abstract][Full Text] [Related]  

    [Next]    [New Search]
    of 28.