292 related articles for article (PubMed ID: 11593406)
1. Biologic sequelae of interleukin-6 induced PI3-K/Akt signaling in multiple myeloma.
Hideshima T; Nakamura N; Chauhan D; Anderson KC
Oncogene; 2001 Sep; 20(42):5991-6000. PubMed ID: 11593406
[TBL] [Abstract][Full Text] [Related]
2. Signal pathways involved in activation of p70S6K and phosphorylation of 4E-BP1 following exposure of multiple myeloma tumor cells to interleukin-6.
Shi Y; Hsu JH; Hu L; Gera J; Lichtenstein A
J Biol Chem; 2002 May; 277(18):15712-20. PubMed ID: 11872747
[TBL] [Abstract][Full Text] [Related]
3. Inhibition of phosphatidylinositol 3'-kinase/AKT signaling promotes apoptosis of primary effusion lymphoma cells.
Uddin S; Hussain AR; Al-Hussein KA; Manogaran PS; Wickrema A; Gutierrez MI; Bhatia KG
Clin Cancer Res; 2005 Apr; 11(8):3102-8. PubMed ID: 15837766
[TBL] [Abstract][Full Text] [Related]
4. PI3-kinase regulates survival of chronic lymphocytic leukemia B-cells by preventing caspase 8 activation.
Plate JM
Leuk Lymphoma; 2004 Aug; 45(8):1519-29. PubMed ID: 15370202
[TBL] [Abstract][Full Text] [Related]
5. Role of the phosphatidylinositol 3-kinase/Akt and mTOR/P70S6-kinase pathways in the proliferation and apoptosis in multiple myeloma.
Pene F; Claessens YE; Muller O; Viguié F; Mayeux P; Dreyfus F; Lacombe C; Bouscary D
Oncogene; 2002 Sep; 21(43):6587-97. PubMed ID: 12242656
[TBL] [Abstract][Full Text] [Related]
6. BCR signals target p27(Kip1) and cyclin D2 via the PI3-K signalling pathway to mediate cell cycle arrest and apoptosis of WEHI 231 B cells.
Banerji L; Glassford J; Lea NC; Thomas NS; Klaus GG; Lam EW
Oncogene; 2001 Nov; 20(50):7352-67. PubMed ID: 11704865
[TBL] [Abstract][Full Text] [Related]
7. Downstream effectors of oncogenic ras in multiple myeloma cells.
Hu L; Shi Y; Hsu JH; Gera J; Van Ness B; Lichtenstein A
Blood; 2003 Apr; 101(8):3126-35. PubMed ID: 12515720
[TBL] [Abstract][Full Text] [Related]
8. The phosphatidylinositol 3-kinase/AKT kinase pathway in multiple myeloma plasma cells: roles in cytokine-dependent survival and proliferative responses.
Tu Y; Gardner A; Lichtenstein A
Cancer Res; 2000 Dec; 60(23):6763-70. PubMed ID: 11118064
[TBL] [Abstract][Full Text] [Related]
9. PI3-K/AKT/FKHR and MAPK signaling cascades are redundantly stimulated by a variety of cytokines and contribute independently to proliferation and survival of multiple myeloma cells.
Lentzsch S; Chatterjee M; Gries M; Bommert K; Gollasch H; Dörken B; Bargou RC
Leukemia; 2004 Nov; 18(11):1883-90. PubMed ID: 15356648
[TBL] [Abstract][Full Text] [Related]
10. Insulin-like growth factor-1 induces adhesion and migration in human multiple myeloma cells via activation of beta1-integrin and phosphatidylinositol 3'-kinase/AKT signaling.
Tai YT; Podar K; Catley L; Tseng YH; Akiyama M; Shringarpure R; Burger R; Hideshima T; Chauhan D; Mitsiades N; Richardson P; Munshi NC; Kahn CR; Mitsiades C; Anderson KC
Cancer Res; 2003 Sep; 63(18):5850-8. PubMed ID: 14522909
[TBL] [Abstract][Full Text] [Related]
11. Suppression of adriamycin-induced apoptosis by sustained activation of the phosphatidylinositol-3'-OH kinase-Akt pathway.
Takeuchi K; Ito F
J Biol Chem; 2004 Jan; 279(2):892-900. PubMed ID: 14570904
[TBL] [Abstract][Full Text] [Related]
12. Overexpression of interferon-gamma-inducible GTPase inhibits coxsackievirus B3-induced apoptosis through the activation of the phosphatidylinositol 3-kinase/Akt pathway and inhibition of viral replication.
Zhang HM; Yuan J; Cheung P; Luo H; Yanagawa B; Chau D; Stephan-Tozy N; Wong BW; Zhang J; Wilson JE; McManus BM; Yang D
J Biol Chem; 2003 Aug; 278(35):33011-9. PubMed ID: 12819192
[TBL] [Abstract][Full Text] [Related]
13. Inhibition of phosphatidylinositol-3 kinase/Akt or mitogen-activated protein kinase signaling sensitizes endothelial cells to TNF-alpha cytotoxicity.
Zhang L; Himi T; Morita I; Murota S
Cell Death Differ; 2001 May; 8(5):528-36. PubMed ID: 11423913
[TBL] [Abstract][Full Text] [Related]
14. The phosphatidylinositol 3-kinase/Akt signaling pathway modulates the endocrine differentiation of trophoblast cells.
Kamei T; Jones SR; Chapman BM; MCGonigle KL; Dai G; Soares MJ
Mol Endocrinol; 2002 Jul; 16(7):1469-81. PubMed ID: 12089343
[TBL] [Abstract][Full Text] [Related]
15. 5(S)-hydroxyeicosatetraenoic acid stimulates DNA synthesis in human microvascular endothelial cells via activation of Jak/STAT and phosphatidylinositol 3-kinase/Akt signaling, leading to induction of expression of basic fibroblast growth factor 2.
Zeng ZZ; Yellaturu CR; Neeli I; Rao GN
J Biol Chem; 2002 Oct; 277(43):41213-9. PubMed ID: 12193593
[TBL] [Abstract][Full Text] [Related]
16. Interleukin-6 activates phosphoinositol-3' kinase in multiple myeloma tumor cells by signaling through RAS-dependent and, separately, through p85-dependent pathways.
Hsu JH; Shi Y; Frost P; Yan H; Hoang B; Sharma S; Gera J; Lichtenstein A
Oncogene; 2004 Apr; 23(19):3368-75. PubMed ID: 15021914
[TBL] [Abstract][Full Text] [Related]
17. SHP2 mediates the protective effect of interleukin-6 against dexamethasone-induced apoptosis in multiple myeloma cells.
Chauhan D; Pandey P; Hideshima T; Treon S; Raje N; Davies FE; Shima Y; Tai YT; Rosen S; Avraham S; Kharbanda S; Anderson KC
J Biol Chem; 2000 Sep; 275(36):27845-50. PubMed ID: 10880513
[TBL] [Abstract][Full Text] [Related]
18. Anti-apoptotic signaling by hepatocyte growth factor/Met via the phosphatidylinositol 3-kinase/Akt and mitogen-activated protein kinase pathways.
Xiao GH; Jeffers M; Bellacosa A; Mitsuuchi Y; Vande Woude GF; Testa JR
Proc Natl Acad Sci U S A; 2001 Jan; 98(1):247-52. PubMed ID: 11134526
[TBL] [Abstract][Full Text] [Related]
19. The PI3-kinase-Akt pathway promotes mesangial cell survival and inhibits apoptosis in vitro via NF-kappa B and Bad.
Shimamura H; Terada Y; Okado T; Tanaka H; Inoshita S; Sasaki S
J Am Soc Nephrol; 2003 Jun; 14(6):1427-34. PubMed ID: 12761242
[TBL] [Abstract][Full Text] [Related]
20. Combined treatment with the checkpoint abrogator UCN-01 and MEK1/2 inhibitors potently induces apoptosis in drug-sensitive and -resistant myeloma cells through an IL-6-independent mechanism.
Dai Y; Landowski TH; Rosen ST; Dent P; Grant S
Blood; 2002 Nov; 100(9):3333-43. PubMed ID: 12384435
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]