234 related articles for article (PubMed ID: 11593572)
1. Reversal of aberrant splicing of beta-thalassemia allele by antisense RNA in vitro and in vivo.
Zeng Y; Gu X; Chen Y; Gong L; Ren Z; Huang S
Chin Med J (Engl); 1999 Feb; 112(2):107-11. PubMed ID: 11593572
[TBL] [Abstract][Full Text] [Related]
2. [Repair of the splicing defect of thalassemic allele beta IVS-2-654 C-->T in cultured human erythroid cells by antisense RNA].
Gu X; Gong L; Zhang W
Zhonghua Yi Xue Za Zhi; 1997 Nov; 77(11):815-8. PubMed ID: 9772473
[TBL] [Abstract][Full Text] [Related]
3. Reversal of aberrant splicing of beta-thalassaemia allele (IVS-2-654 C-->T) by antisense RNA expression vector in cultured human erythroid cells.
Gong L; Gu XF; Chen YD; Ren ZR; Huang SZ; Zeng YT
Br J Haematol; 2000 Oct; 111(1):351-8. PubMed ID: 11091224
[TBL] [Abstract][Full Text] [Related]
4. Correction of aberrant pre-mRNA splicing by antisense oligonucleotides in beta-thalassemia Egyptian patients with IVSI-110 mutation.
El-Beshlawy A; Mostafa A; Youssry I; Gabr H; Mansour IM; El-Tablawy M; Aziz M; Hussein IR
J Pediatr Hematol Oncol; 2008 Apr; 30(4):281-4. PubMed ID: 18391696
[TBL] [Abstract][Full Text] [Related]
5. Repression of aberrant splicing in human beta-globin pre-mRNA with HbE mutation by antisense oligoribonucleotide or splicing factor SF2/ASF.
Shirohzu H; Yamaza H; Fukumaki Y
Int J Hematol; 2000 Jul; 72(1):28-33. PubMed ID: 10979205
[TBL] [Abstract][Full Text] [Related]
6. In vitro expression of beta-thalassaemia gene (IVS1-1G>C) reveals complete inactivation of the normal 5' splice site and alternative aberrant RNA splicing.
Fujihara N; Yamauchi K; Hirota-Kawadobora M; Ishikawa S; Tozuka M; Ishii E; Katsuyama T; Okumura N; Taniguchi S
Ann Clin Biochem; 2007 Nov; 44(Pt 6):573-8. PubMed ID: 17961316
[TBL] [Abstract][Full Text] [Related]
7. Amelioration of beta654-thalassemia in mouse model with the knockdown of aberrantly spliced beta-globin mRNA.
Xie S; Li W; Ren Z; Zhang J; Guo X; Wang S; Huang S; Zeng F; Zeng YT
J Genet Genomics; 2008 Oct; 35(10):595-601. PubMed ID: 18937916
[TBL] [Abstract][Full Text] [Related]
8. The studies of hemoglobinopathies and thalassemia in China--the experiences in Shanghai Institute of Medical Genetics.
Zeng Y; Huang S
Clin Chim Acta; 2001 Nov; 313(1-2):107-11. PubMed ID: 11694246
[TBL] [Abstract][Full Text] [Related]
9. Restoration of the balanced alpha/beta-globin gene expression in beta654-thalassemia mice using combined RNAi and antisense RNA approach.
Xie SY; Ren ZR; Zhang JZ; Guo XB; Wang QX; Wang S; Lin D; Gong XL; Li W; Huang SZ; Zeng F; Zeng YT
Hum Mol Genet; 2007 Nov; 16(21):2616-25. PubMed ID: 17716993
[TBL] [Abstract][Full Text] [Related]
10. Repair of thalassemic human beta-globin mRNA in mammalian cells by antisense oligonucleotides.
Sierakowska H; Sambade MJ; Agrawal S; Kole R
Proc Natl Acad Sci U S A; 1996 Nov; 93(23):12840-4. PubMed ID: 8917506
[TBL] [Abstract][Full Text] [Related]
11. Antisense oligodeoxynucleotides selectively suppress expression of the mutant alpha 2(I) collagen allele in type IV osteogenesis imperfecta fibroblasts. A molecular approach to therapeutics of dominant negative disorders.
Wang Q; Marini JC
J Clin Invest; 1996 Jan; 97(2):448-54. PubMed ID: 8567966
[TBL] [Abstract][Full Text] [Related]
12. High-level expression of hemoglobin A in human thalassemic erythroid progenitor cells following lentiviral vector delivery of an antisense snRNA.
Vacek MM; Ma H; Gemignani F; Lacerra G; Kafri T; Kole R
Blood; 2003 Jan; 101(1):104-11. PubMed ID: 12393543
[TBL] [Abstract][Full Text] [Related]
13. Repair of a splicing defect in erythroid cells from patients with beta-thalassemia/HbE disorder.
Suwanmanee T; Sierakowska H; Fucharoen S; Kole R
Mol Ther; 2002 Dec; 6(6):718-26. PubMed ID: 12498768
[TBL] [Abstract][Full Text] [Related]
14. Spliceosome-mediated RNA trans-splicing as a tool for gene therapy.
Puttaraju M; Jamison SF; Mansfield SG; Garcia-Blanco MA; Mitchell LG
Nat Biotechnol; 1999 Mar; 17(3):246-52. PubMed ID: 10096291
[TBL] [Abstract][Full Text] [Related]
15. Beta globin gene inhibition by antisense RNA transcripts.
Xu L; Ferry AE; Monteiro C; Pace BS
Gene Ther; 2000 Mar; 7(5):438-44. PubMed ID: 10694826
[TBL] [Abstract][Full Text] [Related]
16. Novel beta-thalassemia trait (IVS I-1 G-->C) in a Japanese family.
Fujihara N; Tozuka M; Ueno I; Yamauchi K; Nakagoshi R; Ishikawa S; Hirota M; Okumura N; Ishii E; Katsuyama T
Am J Hematol; 2003 Jan; 72(1):64-6. PubMed ID: 12508270
[TBL] [Abstract][Full Text] [Related]
17. Engineered U7 snRNA mediates sustained splicing correction in erythroid cells from β-thalassemia/HbE patients.
Preedagasamzin S; Nualkaew T; Pongrujikorn T; Jinawath N; Kole R; Fucharoen S; Jearawiriyapaisarn N; Svasti S
Biochem Biophys Res Commun; 2018 Apr; 499(1):86-92. PubMed ID: 29550480
[TBL] [Abstract][Full Text] [Related]
18. Double-target antisense U7 snRNAs promote efficient skipping of an aberrant exon in three human beta-thalassemic mutations.
Suter D; Tomasini R; Reber U; Gorman L; Kole R; Schümperli D
Hum Mol Genet; 1999 Dec; 8(13):2415-23. PubMed ID: 10556289
[TBL] [Abstract][Full Text] [Related]
19. Successful correction of the human Cooley's anemia beta-thalassemia major phenotype using a lentiviral vector flanked by the chicken hypersensitive site 4 chromatin insulator.
Malik P; Arumugam PI; Yee JK; Puthenveetil G
Ann N Y Acad Sci; 2005; 1054():238-49. PubMed ID: 16339671
[TBL] [Abstract][Full Text] [Related]
20. Restoration of correct splicing in thalassemic pre-mRNA by antisense oligonucleotides.
Dominski Z; Kole R
Proc Natl Acad Sci U S A; 1993 Sep; 90(18):8673-7. PubMed ID: 8378346
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]