These tools will no longer be maintained as of December 31, 2024. Archived website can be found here. PubMed4Hh GitHub repository can be found here. Contact NLM Customer Service if you have questions.


BIOMARKERS

Molecular Biopsy of Human Tumors

- a resource for Precision Medicine *

87 related articles for article (PubMed ID: 11595236)

  • 21. Role of metals in the reaction catalyzed by protein farnesyltransferase.
    Saderholm MJ; Hightower KE; Fierke CA
    Biochemistry; 2000 Oct; 39(40):12398-405. PubMed ID: 11015220
    [TBL] [Abstract][Full Text] [Related]  

  • 22. Characterization of a leucine aminopeptidase from Toxoplasma gondii.
    Jia H; Nishikawa Y; Luo Y; Yamagishi J; Sugimoto C; Xuan X
    Mol Biochem Parasitol; 2010 Mar; 170(1):1-6. PubMed ID: 19931316
    [TBL] [Abstract][Full Text] [Related]  

  • 23. Potent inhibitors of farnesyltransferase and geranylgeranyltransferase-I.
    Nguyen DN; Stump CA; Walsh ES; Fernandes C; Davide JP; Ellis-Hutchings M; Robinson RG; Williams TM; Lobell RB; Huber HE; Buser CA
    Bioorg Med Chem Lett; 2002 May; 12(9):1269-73. PubMed ID: 11965368
    [TBL] [Abstract][Full Text] [Related]  

  • 24. Chromatographic assay and peptide substrate characterization of partially purified farnesyl- and geranylgeranyltransferases from rat brain cytosol.
    Boutin JA; Marande W; Goussard M; Loynel A; Canet E; Fauchere JL
    Arch Biochem Biophys; 1998 Jun; 354(1):83-94. PubMed ID: 9633601
    [TBL] [Abstract][Full Text] [Related]  

  • 25. Structure based design of benzophenone-based non-thiol farnesyltransferase inhibitors.
    Schlitzer M
    Curr Pharm Des; 2002; 8(19):1713-22. PubMed ID: 12171543
    [TBL] [Abstract][Full Text] [Related]  

  • 26. Carboxy-terminal CVLS-sequence-specific protein farnesyltransferase from the eyes of the shrimp Penaeus japonicus: purification and characterization.
    Wu CS; Chuang NN
    J Exp Zool; 1996 Aug; 275(5):346-54. PubMed ID: 8691187
    [TBL] [Abstract][Full Text] [Related]  

  • 27. Effects of statins and farnesyltransferase inhibitors on the development and progression of cancer.
    Graaf MR; Richel DJ; van Noorden CJ; Guchelaar HJ
    Cancer Treat Rev; 2004 Nov; 30(7):609-41. PubMed ID: 15531395
    [TBL] [Abstract][Full Text] [Related]  

  • 28. Conversion of protein farnesyltransferase to a geranylgeranyltransferase.
    Terry KL; Casey PJ; Beese LS
    Biochemistry; 2006 Aug; 45(32):9746-55. PubMed ID: 16893176
    [TBL] [Abstract][Full Text] [Related]  

  • 29. Inhibition of the prenylation of K-Ras, but not H- or N-Ras, is highly resistant to CAAX peptidomimetics and requires both a farnesyltransferase and a geranylgeranyltransferase I inhibitor in human tumor cell lines.
    Lerner EC; Zhang TT; Knowles DB; Qian Y; Hamilton AD; Sebti SM
    Oncogene; 1997 Sep; 15(11):1283-8. PubMed ID: 9315095
    [TBL] [Abstract][Full Text] [Related]  

  • 30. Farnesylation of nonpeptidic thiol compounds by protein farnesyltransferase.
    Hightower KE; Casey PJ; Fierke CA
    Biochemistry; 2001 Jan; 40(4):1002-10. PubMed ID: 11170422
    [TBL] [Abstract][Full Text] [Related]  

  • 31. Modulation of the zinc(II) center in protein farnesyltransferase by mutagenesis of the zinc(II) ligands.
    Harris CM; Derdowski AM; Poulter CD
    Biochemistry; 2002 Aug; 41(33):10554-62. PubMed ID: 12173942
    [TBL] [Abstract][Full Text] [Related]  

  • 32. Both farnesyltransferase and geranylgeranyltransferase I inhibitors are required for inhibition of oncogenic K-Ras prenylation but each alone is sufficient to suppress human tumor growth in nude mouse xenografts.
    Sun J; Qian Y; Hamilton AD; Sebti SM
    Oncogene; 1998 Mar; 16(11):1467-73. PubMed ID: 9525745
    [TBL] [Abstract][Full Text] [Related]  

  • 33. Enzymology and biology of CaaX protein prenylation.
    Fu HW; Casey PJ
    Recent Prog Horm Res; 1999; 54():315-42; discussion 342-3. PubMed ID: 10548882
    [TBL] [Abstract][Full Text] [Related]  

  • 34. Protein farnesyltransferase: flexible docking studies on inhibitors using computational modeling.
    Guida WC; Hamilton AD; Crotty JW; Sebti SM
    J Comput Aided Mol Des; 2005 Dec; 19(12):871-85. PubMed ID: 16607571
    [TBL] [Abstract][Full Text] [Related]  

  • 35. Dual protein farnesyltransferase-geranylgeranyltransferase-I inhibitors as potential cancer chemotherapeutic agents.
    deSolms SJ; Ciccarone TM; MacTough SC; Shaw AW; Buser CA; Ellis-Hutchings M; Fernandes C; Hamilton KA; Huber HE; Kohl NE; Lobell RB; Robinson RG; Tsou NN; Walsh ES; Graham SL; Beese LS; Taylor JS
    J Med Chem; 2003 Jul; 46(14):2973-84. PubMed ID: 12825937
    [TBL] [Abstract][Full Text] [Related]  

  • 36. Peptidomimetic inhibitors of protein farnesyltransferase show potent antimalarial activity.
    Ohkanda J; Lockman JW; Yokoyama K; Gelb MH; Croft SL; Kendrick H; Harrell MI; Feagin JE; Blaskovich MA; Sebti SM; Hamilton AD
    Bioorg Med Chem Lett; 2001 Mar; 11(6):761-4. PubMed ID: 11277514
    [TBL] [Abstract][Full Text] [Related]  

  • 37. Identification of dihydroorotate dehydrogenase as a relevant drug target for 1-hydroxyquinolones in Toxoplasma gondii.
    Hegewald J; Gross U; Bohne W
    Mol Biochem Parasitol; 2013 Jul; 190(1):6-15. PubMed ID: 23747278
    [TBL] [Abstract][Full Text] [Related]  

  • 38. Combination of the novel farnesyltransferase inhibitor RPR130401 and the geranylgeranyltransferase-1 inhibitor GGTI-298 disrupts MAP kinase activation and G(1)-S transition in Ki-Ras-overexpressing transformed adrenocortical cells.
    Mazet JL; Padieu M; Osman H; Maume G; Mailliet P; Dereu N; Hamilton AD; Lavelle F; Sebti SM; Maume BF
    FEBS Lett; 1999 Oct; 460(2):235-40. PubMed ID: 10544242
    [TBL] [Abstract][Full Text] [Related]  

  • 39. Non-thiol farnesyltransferase inhibitors: utilization of the near aryl binding site by 5-arylacetylaminobenzophenones.
    Mitsch A; Böhm M; Sattler I; Schlitzer M
    Arch Pharm (Weinheim); 2004 Apr; 337(4):213-8. PubMed ID: 15065081
    [TBL] [Abstract][Full Text] [Related]  

  • 40. Protein farnesyltransferase inhibitors.
    Ayral-Kaloustian S; Salaski EJ
    Curr Med Chem; 2002 May; 9(10):1003-32. PubMed ID: 12733981
    [TBL] [Abstract][Full Text] [Related]  

    [Previous]   [Next]    [New Search]
    of 5.