216 related articles for article (PubMed ID: 11595409)
1. Repair of O(6)-methylguanine is not affected by thymine base pairing and the presence of MMR proteins.
Lips J; Kaina B
Mutat Res; 2001 Nov; 487(1-2):59-66. PubMed ID: 11595409
[TBL] [Abstract][Full Text] [Related]
2. Chromosomal instability, reproductive cell death and apoptosis induced by O6-methylguanine in Mex-, Mex+ and methylation-tolerant mismatch repair compromised cells: facts and models.
Kaina B; Ziouta A; Ochs K; Coquerelle T
Mutat Res; 1997 Nov; 381(2):227-41. PubMed ID: 9434879
[TBL] [Abstract][Full Text] [Related]
3. Apoptosis triggered by DNA damage O6-methylguanine in human lymphocytes requires DNA replication and is mediated by p53 and Fas/CD95/Apo-1.
Roos W; Baumgartner M; Kaina B
Oncogene; 2004 Jan; 23(2):359-67. PubMed ID: 14724564
[TBL] [Abstract][Full Text] [Related]
4. The bacterial alkyltransferase-like (eATL) protein protects mammalian cells against methylating agent-induced toxicity.
Tomaszowski KH; Aasland D; Margison GP; Williams E; Pinder SI; Modesti M; Fuchs RP; Kaina B
DNA Repair (Amst); 2015 Apr; 28():14-20. PubMed ID: 25703834
[TBL] [Abstract][Full Text] [Related]
5. Brca2/Xrcc2 dependent HR, but not NHEJ, is required for protection against O(6)-methylguanine triggered apoptosis, DSBs and chromosomal aberrations by a process leading to SCEs.
Roos WP; Nikolova T; Quiros S; Naumann SC; Kiedron O; Zdzienicka MZ; Kaina B
DNA Repair (Amst); 2009 Jan; 8(1):72-86. PubMed ID: 18840549
[TBL] [Abstract][Full Text] [Related]
6. Chemotherapy-induced O(6)-benzylguanine-resistant alkyltransferase mutations in mismatch-deficient colon cancer.
Liu L; Schwartz S; Davis BM; Gerson SL
Cancer Res; 2002 Jun; 62(11):3070-6. PubMed ID: 12036916
[TBL] [Abstract][Full Text] [Related]
7. Development of a new application of the comet assay to assess levels of O6-methylguanine in genomic DNA (CoMeth).
Ramos AA; Pedro DF; Lima CF; Collins AR; Pereira-Wilson C
Free Radic Biol Med; 2013 Jul; 60():41-8. PubMed ID: 23391575
[TBL] [Abstract][Full Text] [Related]
8. Triazene compounds: mechanism of action and related DNA repair systems.
Marchesi F; Turriziani M; Tortorelli G; Avvisati G; Torino F; De Vecchis L
Pharmacol Res; 2007 Oct; 56(4):275-87. PubMed ID: 17897837
[TBL] [Abstract][Full Text] [Related]
9. Processing of O6-methylguanine into DNA double-strand breaks requires two rounds of replication whereas apoptosis is also induced in subsequent cell cycles.
Quiros S; Roos WP; Kaina B
Cell Cycle; 2010 Jan; 9(1):168-78. PubMed ID: 20016283
[TBL] [Abstract][Full Text] [Related]
10. MGMT: key node in the battle against genotoxicity, carcinogenicity and apoptosis induced by alkylating agents.
Kaina B; Christmann M; Naumann S; Roos WP
DNA Repair (Amst); 2007 Aug; 6(8):1079-99. PubMed ID: 17485253
[TBL] [Abstract][Full Text] [Related]
11. A single cycle of treatment with temozolomide, alone or combined with O(6)-benzylguanine, induces strong chemoresistance in melanoma cell clones in vitro: role of O(6)-methylguanine-DNA methyltransferase and the mismatch repair system.
Alvino E; Castiglia D; Caporali S; Pepponi R; Caporaso P; Lacal PM; Marra G; Fischer F; Zambruno G; Bonmassar E; Jiricny J; D'Atri S
Int J Oncol; 2006 Oct; 29(4):785-97. PubMed ID: 16964376
[TBL] [Abstract][Full Text] [Related]
12. Mechanisms and consequences of methylating agent-induced SCEs and chromosomal aberrations: a long road traveled and still a far way to go.
Kaina B
Cytogenet Genome Res; 2004; 104(1-4):77-86. PubMed ID: 15162018
[TBL] [Abstract][Full Text] [Related]
13. Nuclear translocation of mismatch repair proteins MSH2 and MSH6 as a response of cells to alkylating agents.
Christmann M; Kaina B
J Biol Chem; 2000 Nov; 275(46):36256-62. PubMed ID: 10954713
[TBL] [Abstract][Full Text] [Related]
14. O6-methylguanine-induced cell death involves exonuclease 1 as well as DNA mismatch recognition in vivo.
Klapacz J; Meira LB; Luchetti DG; Calvo JA; Bronson RT; Edelmann W; Samson LD
Proc Natl Acad Sci U S A; 2009 Jan; 106(2):576-81. PubMed ID: 19124772
[TBL] [Abstract][Full Text] [Related]
15. Transfection and expression of human O6-methylguanine-DNA methyltransferase (MGMT) cDNA in Chinese hamster cells: the role of MGMT in protection against the genotoxic effects of alkylating agents.
Kaina B; Fritz G; Mitra S; Coquerelle T
Carcinogenesis; 1991 Oct; 12(10):1857-67. PubMed ID: 1657427
[TBL] [Abstract][Full Text] [Related]
16. Induction of c-fos, c-jun, junB and junD mRNA and AP-1 by alkylating mutagens in cells deficient and proficient for the DNA repair protein O6-methylguanine-DNA methyltransferase (MGMT) and its relationship to cell death, mutation induction and chromosomal instability.
Dosch J; Kaina B
Oncogene; 1996 Nov; 13(9):1927-35. PubMed ID: 8934539
[TBL] [Abstract][Full Text] [Related]
17. BER, MGMT, and MMR in defense against alkylation-induced genotoxicity and apoptosis.
Kaina B; Ochs K; Grösch S; Fritz G; Lips J; Tomicic M; Dunkern T; Christmann M
Prog Nucleic Acid Res Mol Biol; 2001; 68():41-54. PubMed ID: 11554312
[TBL] [Abstract][Full Text] [Related]
18. Apoptosis in malignant glioma cells triggered by the temozolomide-induced DNA lesion O6-methylguanine.
Roos WP; Batista LF; Naumann SC; Wick W; Weller M; Menck CF; Kaina B
Oncogene; 2007 Jan; 26(2):186-97. PubMed ID: 16819506
[TBL] [Abstract][Full Text] [Related]
19. Repair and removal of azoxymethane-induced O6-methylguanine in rat colon by O6-methylguanine DNA methyltransferase and apoptosis.
Nyskohus LS; Watson AJ; Margison GP; Le Leu RK; Kim SW; Lockett TJ; Head RJ; Young GP; Hu Y
Mutat Res Genet Toxicol Environ Mutagen; 2013 Dec; 758(1-2):80-6. PubMed ID: 24140386
[TBL] [Abstract][Full Text] [Related]
20. ATR kinase activation mediated by MutSalpha and MutLalpha in response to cytotoxic O6-methylguanine adducts.
Yoshioka K; Yoshioka Y; Hsieh P
Mol Cell; 2006 May; 22(4):501-10. PubMed ID: 16713580
[TBL] [Abstract][Full Text] [Related]
[Next] [New Search]